MARCOS NAOYUKI SAMANO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cardio-Pneumologia, Faculdade de Medicina - Docente
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
8 resultados
Resultados de Busca
Agora exibindo 1 - 8 de 8
- Cytokine levels in pleural fluid as markers of acute rejection after lung transplantation(2014) CAMARGO, Priscila Cilene Leon Bueno de; AFONSO JR., Jose Eduardo; SAMANO, Marcos Naoyuki; ACENCIO, Milena Marques Pagliarelli; ANTONANGELO, Leila; TEIXEIRA, Ricardo Henrique de Oliveira BragaOur objective was to determine the levels of lactate dehydrogenase, IL-6, IL-8, and VEGF, as well as the total and differential cell counts, in the pleural fluid of lung transplant recipients, correlating those levels with the occurrence and severity of rejection. We analyzed pleural fluid samples collected from 18 patients at various time points (up to postoperative day 4). The levels of IL-6, IL-8, and VEGF tended to elevate in parallel with increases in the severity of rejection. Our results suggest that these levels are markers of acute graft rejection in lung transplant recipients.
- Ex-Vivo Lung Perfusion for Infected Non-Acceptable Donor Lungs: A Pilot Study(2014) SAMANO, M. N.; ABDALLA, L. G.; FERNANDES, L. M.; NEPOMUCENO, N. A.; BRAGA, K. A. Oliveira; AZEVEDO-PEREIRA, A. E.; PEGO-FERNANDES, P. M.
- Pediatric lung transplantation: 10 years of experience(2014) CAMARGO, Priscila C. L. B.; PATO, Eduardo Z. S.; CAMPOS, Silvia V.; AFONSO JR., Jose E.; CARRARO, Rafael M.; COSTA, Andre N.; TEIXEIRA, Ricardo H. O. B.; SAMANO, Marcos N.; PEGO-FERNANDES, Paulo M.Lung transplantation is a well-established treatment for advanced lung diseases. In children, the diseases that most commonly lead to the need for a transplantation are cystic fibrosis, pulmonary hypertension, and bronchiolitis. However, the number of pediatric lung transplantations being performed is low compared with the number of transplants performed in the adult age group. The objective of this study was to demonstrate our experience with pediatric lung transplants over a 10-year period in a program initially designed for adults.
- Posterior Reversible Encephalopathy Syndrome in Lung Transplantation: 5 Case Reports(2014) ARIMURA, F. E.; CAMARGO, P. C. L. B.; COSTA, A. N.; TEIXEIRA, R. H. O. B.; CARRARO, R. M.; AFONSO JR., J. E.; CAMPOS, S. V.; SAMANO, M. N.; FERNANDES, L. M.; ABDALLA, L. G.; PEGO-FERNANDES, P. M.Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiologic entity characterized by typical neurologic symptoms with characteristic cerebral image alterations. It has been reported in solid organ transplantations, especially related to the use of calcineurin inhibitors. The incidence of PRES in lung transplantation is unknown and probably under-reported in the literature. Here we describe 5 cases of PRES after bilateral lung transplantation. One of the reported cases was the first in the literature in which the neurologic onset precluded the introduction of calcineurin inhibitor. Therefore, although calcineurin inhibitors are known to play an important role in the development of PRES in the setting of lung transplantation, other causes seems to be involved in the physiopathology of this syndrome.
conferenceObject Evaluation Of Bronchial Anastomosis Stenosis After Lung Transplantation With Electrical Impedance Tomography: A Case Report(2014) CAMARGO, P. C. L. B. D.; AFONSO JR., J. E.; COSTA, A. N.; CARRARO, R. M.; CAMPOS, S. V.; ABDALLA, L. G.; FERNANDES, L. M.; SAMANO, M. N.; TORSANI, V.; PEGO-FERNANDES, P. M.; AMATO, M. B. D. P.- Fungal Infection by Mucorales Order in Lung Transplantation: 4 Case Reports(2014) NETO, F. M. F. D.; CAMARGO, P. C. L. B.; COSTA, A. N.; TEIXEIRA, R. H. O. B.; CARRARO, R. M.; AFONSO JR., J. E.; CAMPOS, S. V.; SAMANO, M. N.; FERNANDES, L. M.; ABDALLA, L. G.; PEGO-FERNANDES, P. M.Mucorales is a fungus that causes systemic, highly lethal infections in immunocompromised patients. The overall mortality of pulmonary mucormycosis can reach 95%. This work is a review of medical records of 200 lung transplant recipients between the years of 2003 and 2013, in order to identify the prevalence of Mucorales in the Lung Transplantation service of Heart Institute (InCor), Hospital das Clinicas da Universidade de Sao Paulo, Brazil, by culture results from bronchoalveolar lavage and necropsy findings. We report 4 cases found at this analyses: 3 in patients with cystic fibrosis and 1 in a patient with bronchiectasis due to Kartagener syndrome. There were 2 unfavorable outcomes related to the presence of Mucorales, 1 by reduction of immunosuppression, another by invasive infection. Another patient died from renal and septic complications from another etiology. One patient was diagnosed at autopsy just 5 days after lung transplantation, with the Mucor inside the pulmonary vein with a precise, well-defined involvement only of donor's segment, leading to previous colonization hypothesis. There are few case reports of Mucorales infection in lung transplantation in the literature. Surveillance for the presence of Mucor can lead to timely fungal treatment and reduce morbidity and mortality in the immunocompromised patients, especially lung transplant recipients.
conferenceObject Venous Thromboembolism: A Retrospective Analysis Of 87 Lung Transplant Patients(2014) DIDIER-NETO, F. M. F.; CAMARGO, P. C. L. B.; COSTA, A. N.; TEIXEIRA, R. H. O. B.; CARRARO, R. M.; AFONSO, J. E.; CAMPOS, S. V.; SAMANO, M. N.; FERNANDES, L. M.; ABDALLA, L. G.; PEGO-FERNANDES, P. M.conferenceObject Posterior Reversible Encephalopathy Syndrome In Lung Transplantation: Report Of Six Cases(2014) ARIMURA, F. E.; CAMARGO, P. C. L. B. D.; TEIXEIRA, R. H. O. B.; CARRARO, R. M.; COSTA, A. N.; AFONSO, J. E.; CAMPOS, S. V.; SAMANO, M. N.; FERNANDES, L. M.; ABDALLA, L. G.; PEGO-FERNANDES, P. M.; CARVALHO, C. R. R.