JULIANO NOVAES CARDOSO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
5 resultados
Resultados de Busca
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conferenceObject Prognosis in advanced heart failure is related to betablocker doses(2013) BARRETTO, A. C. Pereira; MELO, D. S. B.; CARLO, C. H. Del; CARDOSO, J. N.; OCHIA, M. E.; MORGADO, P. C.; MUNHOZ, R. T.- Diuretic titration based on weight change in decompensated congestive heart failure: A randomized trial(2013) CARDOSO, J. N.; OCHIAI, M. E.; OLIVEIRA, M. T.; REIS, C. M.; CURIATI, M.; VIEIRA, K. R.; BARRETTO, A. C. P.
conferenceObject Use of non-invasive continuous hemodynamic monitoring in decompensated heart failure(2013) LIMA, M. Villaca; OCHIAI, M. E.; CARDOSO, J. N.; VIEIRA, K. R.; CARDOSO, M. N.; BRANCALHAO, E. C. O.; BARRETTO, A. C. P.- Papel dos níveis de BNP no prognóstico da insuficiência cardíaca avançada descompensada(2013) PEREIRA-BARRETTO, Antonio Carlos; CARLO, Carlos Henrique Del; CARDOSO, Juliano Novaes; OCHIAI, Marcelo Eid; LIMA, Marcelo Villaca; CURIATI, Milena Cardoso; SCIPIONI, Airton Roberto; RAMIRES, Jose Antonio FranchiniBackground: Heart failure (HF) is a condition with poor outcome, especially in advanced cases. Determination of B-type natriuretic peptide (BNP) levels is useful in the diagnosis of cardiac decompensation and has also been proving useful in the prognostic evaluation. Objectives: To verify whether BNP levels are able to identify patients with a poorer outcome and whether it is an independent prognostic factor considering age, gender, cardiac and renal functions, as well as the cause of heart disease. Methods: 189 patients in functional class III/IV advanced HF were studied. All had systolic dysfunction and had their BNP levels determined during hospitalization. Variables related to mortality were studied using univariate and multivariate analyses. Results: BNP levels were higher in patients who died in the first year of follow-up (1,861.9 versus 1,408.1 pg/dL; p = 0.044) and in chagasic patients (1,985 versus 1,452 pg/mL; p = 0.001); the latter had a higher mortality rate in the first year of follow-up (56% versus 35%; p = 0.010). The ROC curve analysis showed that the BNP level of 1,400 pg/mL was the best predictor of events; high levels were associated with lower LVEF (0.23 versus 0.28; p = 0.002) and more severe degree of renal dysfunction (mean urea 92 versus 74.5 mg/dL; p = 0.002). Conclusion: In advanced HF, high BNP levels identified patients at higher risk of a poorer outcome. Chagasic patients showed higher BNP levels than those with heart diseases of other causes, and have poorer prognosis (Arq Bras Cardiol. 2013; 100(3): 281-287).
conferenceObject Impact of genetic polymorphisms in end-stage heart failure prognosis after rapid up titration of beta-blockers(2013) MELO, D. M.; BARRETTO, A. C. P. B.; OLIVEIRA, A. I. O.; CARDOSO, J. N. C.; MELO, F. S. A. M.; OCHIAI, M. E. O.; MORGADO, P. C. M.; RAMIREZ, J. A. F. R.