PATRICIA MOMOYO YOSHIMURA ZITELLI

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Instituto Central, Hospital das Clínicas, Faculdade de Medicina

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  • conferenceObject
    Availability and affordability of services affects outcome in hospitalized patients with cirrhosis-results from CLEARED consortium
    (2023) CHOUDHURY, Ashok; XIE, Qing; TOPAZIAN, Mark; SARIN, Shiv Kumar; HAYES, Peter; TORRE, Aldo; DESALEGN, Hailemichael; IDILMAN, Ramazan; CAO, Zhujun; KUMAR, Shiva; GADANO, Adrian; PRUDENCE, Alexander; ZITELLI, Patricia; BERA, Chinmay; DAHIYA, Monica; LAH, Ponan Ponan Claude Regis; ARRESE, Marco; GUAN, Jin; WANG, Yingling; SU, Man; WANG, Xinrui; PENG, Feng; WANG, Wei; YIN, Dedong; CAI, Yijing; DONG, Fuchen; LIU, Jing; YAN, Libo; WEI, Linlin; XU, Zhen; GAO, Haibing; LI, Beiling; ZHANG, Yanyun; DENG, Huan; DEBZI, Nabil; VENKATACHALAPATHY, Suresh Vasan; FAULKES, Rosemary; FORREST, Ewan; KENNEDY, James; FUNG, Yan Yue James; RABINOWICH, Liane; SHARMA, Mithun; YEGURLA, Jatin; JOTHIMANI, Dinesh; KUMAR, Ashish; GOEL, Ashish; ROY, Akash; PRAHARAJ, Dibya Lochan; CABRERA, Araceli Bravo; GUTIERREZ, Oscar Morales; PINEDA, Abraham Ramos; MADE, Lilian Torres; TELLEZ, Francisco Felix; ARSYAD, Nik M. A. Nik; NYAM, David P.; PATWA, Yashwi Haresh Kumar; LUN, Liou Wei; WEJNARUEMARN, Salisa; HAKTANIYAN, Busra; ASLAN, Rahmi; BARUTCU, Sezgin; UYSAL, Alper; KOSAY, Tolga; DINCER, Dinc; FALLAHZADEH, Mohammad Amin; RAHEMATPURA, Suditi; BAYNE, David; FILIPEK, Natalia; SHESHADRI, Somya; CABELLO, Ricardo; ALVARES-DA-SILVA, Mario; GEORGE, Jacob; WONG, Florence; BUSH, Brian; THACKER, Leroy; BAJAJ, Jasmohan S.
  • article 1 Citação(ões) na Scopus
    Direct-acting antivirals for chronic hepatitis C treatment: The experience of two tertiary university centers in Brazil
    (2022) LOURENCO, Mariana Sandoval; ZITELLI, Patricia Momoyo Y.; CUNHA-SILVA, Marlone; OLIVEIRA, Arthur Ivan N.; OLIVEIRA, Claudia P.; SEVA-PEREIRA, Tiago; CARRILHO, Flair Jose; PESSOA, Mario G.; MAZO, Daniel F.
    BACKGROUND Hepatitis C virus (HCV) treatment has undergone major changes in recent years. Previous interferon-based therapies have been replaced by oral direct-acting antivirals (DAA) regimens, with high sustained virologic response (SVR) rates, and a lower incidence of adverse events (AEs). AIM To evaluate the efficacy and safety of DAAs for HCV treatment in subjects from two tertiary university centers in Brazil. METHODS This is a multicenter retrospective cohort study of 532 patients with chronic hepatitis C (CHC), undergoing treatment with interferon-free regimens from November 2015 to November 2019. The therapeutic regimen was defined by the current Brazilian guidelines for HCV management at the time of treatment. Demographic, anthropometric, clinical, and laboratory variables were evaluated. SVRs were assessed at 12 to 24 wk after therapy by intention-to-treat (ITT), and modified ITT (m-ITT) analysis. AEs and serious adverse events (SAEs) were registered. In the statistical analysis, a P value of < 0.05 was considered significant. RESULTS The mean age was 56.88 years, with 415 (78.5%) being HCV genotype 1, followed by genotype 3 (20.1%). Moreover, 306 (57.5%) subjects had cirrhosis, and a third of them had decompensated cirrhosis. Sofosbuvir (SOF) plus daclatasvir ribavirin was the most frequently used treatment (66.9%), followed by SOF plus simeprevir (21.2%). The overall ITT SVR was 92.6% (493/532), while the m-ITT SVR was 96.8% (493/509). Variables associated with treatment failure via ITT evaluation were hepatic encephalopathy (OR: 4.320; 95%CI: 1.920-9.721, P = 0.0004), presence of esophageal varices (OR: 2.381; 95%CI: 1.137-4.988, P = 0.0215), previous portal hypertensive bleeding (OR: 2.756; 95%CI: 1.173-6.471, P = 0.02), higher model for end-stage liver disease scores (OR: 1.143, 95%CI: 1.060-1.233, P = 0.0005), lower serum albumin levels (OR: 0.528, 95%CI: 0.322-0.867, P = 0.0115), higher serum creatinine (OR: 1.117, 95%CI: 1.056-1.312, P = 0.0033), and international normalized ratio (INR) levels (OR: 5.542, 95%CI: 2.023-15.182, P = 0.0009). AEs were reported in 41.1% (211/514) of patients, and SAEs in 3.7%. The female gender, higher body mass index, esophageal varices, higher INR values, and longer treatment duration were independently associated with AE occurrence. CONCLUSION Treatment with oral DAAs attains a high SVR rate, with fewer SAEs in a real-life cohort of subjects with CHC, from two tertiary university centers in Brazil.
  • article 0 Citação(ões) na Scopus
    Lysosomal Acid Lipase Deficiency in the Etiological Investigation of Cryptogenic Liver Disease in Adults: A Multicenter Brazilian Study
    (2023) CANDOLO, Aline Coelho Rocha; CANCADO, Guilherme Grossi Lopes; ZITELLI, Patricia Momoyo; MAZO, Daniel Ferraz de Campos; OLIVEIRA, Claudia Pinto Marques; CUNHA-SILVA, Marlone; GRECA, Raquel Dias; ARAUJO, Roberta Chaves; ALUSTAU, Amanda Sacha Paulino Tolentino; COUTO, Claudia Alves; NARDELLI, Mateus Jorge; LIMA, Roque Gabriel Rezende de; FARIAS, Alberto Queiroz; CARRILHO, Flair Jose; PESSOA, Mario Guimaraes
    Background: Lysosomal acid lipase deficiency (LAL-D) is a rare genetic disease associated with the deregulation of lipid metabolism, leading to atherosclerosis, dyslipidemia, and hepatic steatosis, with potential progression to cirrhosis. Our study aims to assess the role of LAL-D in the setting of cryptogenic liver disease. Methods: A large multicenter cross-sectional study was conducted, which included 135 patients with cryptogenic liver disease from four liver centers in Brazil. All patients were submitted to the investigation of LAL enzyme activity on dried blood spots. Results: Three patients (two female) presented levels of LAL below the reference limit, compatible with LAL-D (2.2%). They had a mean age of 43.9 +/- 10.1 years and a mean body-mass index (BMI) of 23.1 +/- 1.7 kg/m2. The mean serum levels of glucose, HDL-cholesterol, and triglycerides were 89.7 +/- 3.2, 21.7 +/- 3.2, and 206.7 +/- 25.5 mg/dL, respectively. All patients had duodenal polyposis with xanthomatous macrophages. LAL-D investigation should be considered for individuals with chronic liver disease of an unknown etiology, especially with a normal BMI, high triglycerides, and low-HDL-cholesterol levels. The identification of LAL-D patients is extremely important since enzyme replacement therapy with Sebelipase Alfa significantly increases their survival.
  • conferenceObject
    PRIVATE INSURANCE ACCESS IS ASSOCIATED WITH HIGHER LIVER TRANSPLANT LISTING AND TRANSPLANT ACCESS AND LOWER MORTALITY COMPARED TO NATIONAL INSURANCES IN A LARGE MULTINATIONAL COHORT OF INPATIENTS WITH CIRRHOSIS
    (2023) BAJAJ, Jasmohan S.; WONG, Florence; XIE, Qing; KAMATH, Patrick S.; TOPAZIAN, Mark; HAYES, Peter C.; TORRE, Aldo; DESALEGN, Hailemichael; IDILMAN, Ramazan; CAO, Zhujun; ALVARES-DA-SILVA, Mario Reis; GEORGE, Jacob; BUSH, Brian J.; THACKER, Leroy R.; SHAW, Jawaid A.; ALBHAISI, Somaya; FISSEHA, Henok; ASRANI, Sumeet; FALLAHZADEH, Mohammad Amin; ALLAH, Belimi Hibat; DEBZI, Nabil; SETO, Wai-Kay; FUNG, James; VARGAS, Hugo E.; BAYNE, David; ALLAM, Dalia; PATWA, Yashwi Haresh Kumar; ARAVINTHAN, Aloysious; VENKATACHALAPATHY, Suresh Vasan; RAJORIYA, Neil; FAULKES, Rosemary; RAJARAM, Ruveena; ARSYAD, Nik Ma Nik; KATCHMAN, Helena; RABINOWICH, Liane; BERA, Chinmay; NAGRAL, Aabha; HAVERI, Ajay; OKEKE, Edith; NYAM, David P.; KUMAR, Shiva; THULUVATH, Paul J.; SHESHADRI, Somya; LEITH, Damien; HUEZO, Maria Sarai Gonzalez; CABRERA, Araceli Bravo; GUTIERREZ, Oscar Morales; KULKARNI, Anand V.; SHARMA, Mithun; EAPEN, C. E.; GOEL, Ashish; DUSEJA, Ajay K.; BETTINGER, Dominik; GANDOTRA, Akash; SCHULTHEISS, Michael; RAMOS-PINEDA, Abraham; TAN, Hiang Keat; LIOU, Wei Lun; BARRADAS, Mauricio Castillo; TREEPRASERTSUK, Sombat; WEJNARUEMARN, Salisa; VELAZQUEZ, Rene Male; MADE, Lilian Torres; KAPPUS, Matthew R.; WEGERMANN, Kara; DANIELLE, Adebayo; BIGGINS, Scott W.; FILIPEK, Natalia; KEAVENY, Andrew Paul; YUNG, Diana; TANDON, Puneeta; DAHIYA, Monica; HAKTANIYAN, Busra; DUARTE-ROJO, Andres; REDDY, K. Rajender Rajender; RAHEMATPURA, Suditi; SARAYA, Anoop; RELA, Mohamed; GUNDUZ, Feyza; ASLAN, Rahmi; YILDIRIM, Abdullah Emre; BARUTCU, Sezgin; ARORA, Anil; KUMAR, Ashish; VERNA, Elizabeth; TUDEHOPE, Fiona; MARCIANO, Sebastian; GADANO, Adrian; KARASU, Zeki; UYSAL, Alper; UCBILEK, Enver; KOSAY, Tolga; VELASCO, Jose Antonio Velarde-Ruiz; FELIX-TELLEZ, Francisco; ADANIR, Haydar; DINCER, Dinc; DHIMAN, Radhakrishna; ROY, Akash; FAISAL, Nabiha; ANAND, Anil Chandra; PRAHARAJ, Dibyalochan; GIBSON, Robert; PRUDENCE, Alexander; XIAN, Yongchao; GUAN, Jin; ZHU, Chuanwu; WANG, Yingling; SU, Man; GAO, Yanhang; WANG, Xinrui; JIANG, Yongfang; PENG, Feng; ZHAO, Caiyan; WANG, Wang; WANG, Lei; YIN, Dedong; LIU, Mingquin; CAI, Yijing; WANG, Xiaozhong; GUO, Feng; ZHANG, Ningping; ZHANG, Wanqin; LI, Hai; DONG, Fuchen; ZHENG, Xin; LIU, Jing; TANG, Hong; YAN, Libo; XU, Bin; WEI, Linlin; GAO, Zhiliang; XU, Zhen; GALLARDO, Jacqueline Cordova; LIN, Minghua; GAO, Haibin; WU, Xiaoping; RAO, Qunfang; ZEKRY, Amany; CHEN, Jinjun; LI, Beiling; LIU, Chenghai; ZHANG, Yanyun; DOYLE, Adam; Vi Nguyen; CHU, Elsa; HU, Peng; DENG, Huan; RIORDAN, Stephen; MICHALCZUK, Matheus; MACQUILLAN, Gerry; LI, Jie; WANG, Jian; FARIAS, Alberto Q.; ZITELI, Patricia; VICTOR, Livia; WONG, Yu Jun; HO, Wei Ling; ALEXOPOULOU, Alexandra; MANI, Iliana; BOBAT, Bilal; YASSER, Fouad; MOSTAFA, Alaa; SONAVANE, Amey; PEREZ-HERNANDEZ, Jose Luis; ZAZUETA, Godolfino Miranda; NEGRILLO, Ricardo Cabello; YEGURLA, Jatin; SARIN, Shiv Kumar; CHOUDHURY, Ashok Kumar
  • article 0 Citação(ões) na Scopus
    Impaired anti-HBV vaccine response in non-cirrhotic chronic HCV is not overcome by double dose regimen: randomized control trial
    (2023) MEDEIROS, Roseane P.; TERRAULT, Norah A.; MAZO, Daniel F.; OLIVEIRA, Claudia P.; DODGE, Jennifer; ZITELLI, Patricia M.; LOPES, Marta H.; CARRILHO, Flair J.; PESSOA, Mario G.
    Introduction and Objectives: Some studies suggest chronic HCV infection diminishes responses to the antiHBV vaccine. We evaluated the efficacy of double versus standard dose HBV vaccination among HCV patients without cirrhosis.Patients and Methods: 141 adults with untreated chronic HCV were randomized to HBV vaccination with double dose (40 mu g) or standard dose (20 mu g) at 0,1 and 6 months; 70 healthy HCV-negative patients given standard dose served as controls. Vaccine response was defined by anti-HBs >= 10 mIU/mL.Results: 128 patients (60 double, 68 standard doses) completed the study. Patients were of median age 52 years, 61% female, 60% fibrosis <2 of 4, and 76% genotype 1 with median 6-log 10 IU/mL HCV RNA. Overall seroprotection rate was 76.7% (95% CI: 65-87) in the 40 mu g versus 73.5% (95% CI: 63-84) in the 20 mu g dose HCV-positive groups (p =0.68) and 91.2% (95%CI:84-99) in HCV-negative controls (p =0.011 and 0.003, respectively). In multivariate logistic regression, vaccine dose (double vs. standard dose) was not associated with vaccine response (OR=0.63, p =0.33). Of 32 HCV-infected patients who were non-responders to 3- doses, 25 received the fourth dose of vaccine. The fourth dose seroconversion rate for the 40 mu g and 20 mu g groups were 45.5% and 21.4%, respectively.Conclusions: In HCV-infected patients without cirrhosis, impaired responses to HBV vaccination cannot be overcome by the use of double dose HBV vaccination, but adding a fourth dose of vaccine for non-responders may be an effective strategy. Other adjuvant measures are needed to enhance seroconversion rates in these patients. Trial register: U 1111-1264-2343 (www.ensaiosclinicos.gov.br)(c) 2022 Fundacion Clinica Medica Sur, A.C.
  • article 3 Citação(ões) na Scopus
    Hepatitis E virus infection increases the risk of diabetes and severity of liver disease in patients with chronic hepatitis C virus infection
    (2021) ZITELLI, Patricia Momoyo Yoshimura; GOMES-GOUVEA, Michele; MAZO, Daniel F.; SINGER, Julio da Motta; OLIVEIRA, Claudia P. M. S.; FARIAS, Alberto Queiroz; PINHO, Joao Renato; TANIGAWA, Ryan Yukimatsu; ALVES, Venancio Avancini Ferreira; CARRILHO, Flair Jose; PESSOA, Mario Guimaraes
    OBJECTIVES: Co-infection with hepatitis A or B viruses may aggravate liver injury in patients infected with hepatitis C virus (HCV). However, few studies have assessed co-infection with hepatitis E virus (HEV) and HCV. Therefore, this study aimed to assess the prevalence and impact of HEV infection among Brazilian patients with chronic HCV infection. METHODS: This observational study included adult patients with chronic HCV infection who were naive to antiviral therapy from January 2013 to March 2016. A total of 181 patients were enrolled, and HEV serology and PCR were performed for all patients. RESULTS: Seropositivity for anti-HEV IgG was detected in 22 (12.0%) patients and anti-HEV immunoglobulin M in 3 (1.6%). HEV RNA showed inconclusive results in nine (4.9%) patients and was undetectable in the remaining patients. HEV serology positive patients had more severe liver disease, characterized by liver fibrosis >= 3 versus <= 2 (p<0.001), Aspartate Aminotransferase-to-Platelet Ratio Index of >= 1.45 (p=0.003), and Fibrosis-4 score of >= 3.25 (p=0.001). Additionally, the odds of HEV-positive patients developing diabetes mellitus were 3.65 (95% CI 1.40-9.52) times the corresponding odds of HEV-negative patients. A case-control-based histological analysis (n=11 HEV-HCV-positive patients and n=22 HCV-positive patients) showed no significant differences between the groups. CONCLUSIONS: This prevalence is higher than that reported in previous studies of the general population in Brazil. Thus, HEV infection may influence the severity of liver disease and may represent an additional risk of developing diabetes mellitus in patients with HCV infection.
  • conferenceObject
    BRAZILIAN PATIENTS WITH CIRRHOSIS HAVE LOWER HOSPITALIZATIONS AND HIGHER MICROBIAL DIVERSITY RELATED TO HEALTHIER DIET COMPARED TO AMERICAN PATIENTS
    (2021) ALVARES-DA-SILVA, Mario R.; OLIVEIRA, Claudia P.; FAGAN, Andrew; LONGO, Larisse; THOEN, Rutiane U.; YOSHIMURA, Patricia M.; FERREIRA, Zitelli Renee M. Tanaka; MCGEORGE, Sara; FARIAS, Alberto Q.; SIKAROODI, Masoumeh; GILLEVET, Patrick M.; BAJAJ, Jasmohan S.
  • article 7 Citação(ões) na Scopus
    Genetic Ancestry, Race, and Severity of Acutely Decompensated Cirrhosis in Latin America
    (2023) FARIAS, Alberto Queiroz; VILALTA, Anna Curto; ZITELLI, Patricia Momoyo; PEREIRA, Gustavo; GONCALVES, Luciana L.; TORRE, Aldo; DIAZ, Juan Manuel; GADANO, Adrian C.; MATTOS, Angelo Z.; MENDES, Liliana S. C.; ALVARES-DA-SILVA, Mario R.; BITTENCOURT, Paulo L.; BENITEZ, Carlos; COUTO, Claudia Alves; MENDIZABAL, Manuel; TOLEDO, Claudio L.; MAZO, Daniel F. C.; BARRADAS, Mauricio Castillo; RAPOSO, Eva M. Uson; PADILLA-MACHACA, P. Martin; MIRANDA, Adelina Zarela Lozano; MALE-VELAZQUEZ, Rene; LYRA, Andre Castro; DAVALOS-MOSCOL, Milagros B.; HERNANDEZ, Jose L. Perez; XIMENES, Rafael O.; SILVA, Giovanni Faria; BELTRAN-GALVIS, Oscar A.; HUEZO, Maria S. Gonzalez; BESSONE, Fernando; ROCHA, Tarciso D. S.; FASSIO, Eduardo; TERRA, Carlos; MARIN, Juan I.; CASAS, Patricia Sierra; PENA-RAMIREZ, Carlos de la; PARERA, Ferran Aguilar; FERNANDES, Flavia; ZAGO-GOMES, Maria da Penha; MENDEZ-GUERRERO, Osvely; MARCIANO, Sebastian; MATTOS, Angelo A.; OLIVEIRA, Joao C.; GUERREIRO, Gabriel T. S.; CODES, Liana; ARRESE, Marco; NARDELLI, Mateus J.; SILVA, Marcelo O.; PALMA-FERNANDEZ, Renato; ALCANTARA, Camila; GARRIDO, Cristina Sanchez; TREBICKA, Jonel; GUSTOT, Thierry; FERNANDEZ, Javier; CLARIA, Joan; JALAN, Rajiv; ANGELI, Paolo; ARROYO, Vicente; MOREAU, Richard; ACLARA Study Collaborators
    BACKGROUND & AIMS: Genetic ancestry or racial differences in health outcomes exist in diseases associated with systemic inflammation (eg, COVID-19). This study aimed to investigate the association of genetic ancestry and race with acute-on chronic liver failure (ACLF), which is characterized by acute systemic inflammation, multi-organ failure, and high risk of short-term death. METHODS: This prospective cohort study analyzed a comprehensive set of data, including genetic ancestry and race among several others, in 1274 patients with acutely decompensated cirrhosis who were nonelectively admitted to 44 hospitals from 7 Latin American countries. RESULTS: Three hundred ninety-five patients (31.0%) had ACLF of any grade at enrollment. Patients with ACLF had a higher median percentage of Native American genetic ancestry and lower median percentage of European ancestry than patients without ACLF (22.6% vs 12.9% and 53.4% vs 59.6%, respectively). The median percentage of African genetic ancestry was low among patients with ACLF and among those without ACLF. In terms of race, a higher percentage of patients with ACLF than patients without ACLF were Native American and a lower percentage of patients with ACLF than patients without ACLF were European American or African American. In multivariable analyses that adjusted for differences in sociodemographic and clinical characteristics, the odds ratio for ACLF at enrollment was 1.08 (95% CI, 1.03-1.13) with Native American genetic ancestry and 2.57 (95% CI, 1.84-3.58) for Native American race vs European American race CONCLUSIONS: In a large cohort of Latin American patients with acutely decompensated cirrhosis, increasing percentages of Native American ancestry and Native American race were factors independently associated with ACLF at enrollment.
  • article 6 Citação(ões) na Scopus
    The role of PNPLA3 and TM6SF2 polymorphisms on liver fibrosis and metabolic abnormalities in Brazilian patients with chronic hepatitis C
    (2021) OLIVEIRA, Arthur Ivan N.; MALTA, Fernanda M.; ZITELLI, Patricia Momoyo Y.; SALLES, Ana Paula M.; GOMES-GOUVEA, Michele S.; NASTRI, Ana Catharina S.; PINHO, Joao Renato R.; CARRILHO, Flair J.; OLIVEIRA, Claudia P.; MENDES-CORREA, Maria Cassia; PESSOA, Mario G.; MAZO, Daniel F.
    BackgroundDespite the growing body of knowledge about TM6SF2 and PNPLA3 polymorphisms in non-alcoholic fatty liver disease, their influence in the spectrum of HCV liver disease is not yet fully defined. Besides that, admixed populations, such as Brazilians, were not included in most of the studies.MethodsThis cross-sectional study enrolled 365 treatment-naive patients with HCV and 134 healthy individuals. TM6SF2 (rs58542926 c.499C>T) and PNPLA3 (rs738409 c.444C>G) polymorphisms were evaluated regarding their association with clinical and laboratory data, histological liver steatosis and fibrosis, and with components of the metabolic syndrome.ResultsIn HCV subjects, the frequencies of TM6SF2 CC and CT+TT were 89% and 11%, while PNPLA3 frequencies of CC and CG+GG were 51.4% and 48.6%. In the univariate logistic regression analysis, the TM6SF2 CT+TT genotype in HCV was associated with significant liver fibrosis (p=0.047; OR 1.953; 95% CI 1.009-3.788). In comparison to the CT+TT genotype, the TM6SF2 CC genotype in HCV was associated with older age (p=0.002), higher frequency of arterial hypertension (p=0.032), obesity (p=0.030), metabolic syndrome (p=0.014) and lower total cholesterol levels (p=0.036). The PNPLA3 GG subjects had lower body mass index than CG/ CC individuals (p=0.047). None of the polymorphisms, or their combinations, was independently associated with hepatic steatosis or fibrosis. On the other hand, older age, lower serum levels of total cholesterol, and higher serum levels of alanine aminotransferase and alkaline phosphatase were associated with liver fibrosis in the multivariate logistic regression analysis.ConclusionIn this evaluation of an admixed HCV population, neither TM6SF2 nor PNPLA3 polymorphisms were independently associated with hepatic steatosis or fibrosis. Other factors seem more influential than these specific polymorphisms in isolation. More studies are warranted to clarify the role of the TM6SF2 and PNPLA3 polymorphisms in Brazilians with HCV.
  • conferenceObject
    REGIONAL DIFFERENCES IN ACUTE KIDNEY INJURY PREVALENCE, CLINICAL CHARACTERISTICS AND PATIENT OUTCOMES IN A MULTI-NATIONAL CONSORTIUM OF INPATIENTS WITH CIRRHOSIS
    (2023) WONG, Florence; GEORGE, Jacob; HAYES, Peter C.; TORRE, Aldo; KAMATH, Patrick S.; XIE, Qing; TOPAZIAN, Mark; DESALEGN, Hailemichael; IDILMAN, Ramazan; ALVARES-DA-SILVA, Mario Reis; CHOUDHURY, Ashok Kumar; ASRANI, Sumeet; VARGAS, Hugo E.; BERA, Chinmay; CAO, Zhujun; SHAW, Jawaid A.; ALBHAISI, Somaya; FISSEHA, Henok; FALLAHZADEH, Mohammad Amin; ALLAH, Belimi Hibat; DEBZI, Nabil; SETO, Wai-Kay; FUNG, James; BAYNE, David; ALLAM, Dalia; PATWA, Yashwi Haresh Kumar; ARAVINTHAN, Aloysious; VENKATACHALAPATHY, Suresh Vasan; RAJORIYA, Neil; FAULKES, Rosemary; RAJARAM, Ruveena; ARSYAD, Nik Ma Nik; KATCHMAN, Helena; RABINOWICH, Liane; NAGRAL, Aabha; HAVERI, Ajay; OKEKE, Edith; NYAM, David P.; KUMAR, Shiva; THULUVATH, Paul J.; SHESHADRI, Somya; LEITH, Damien; FORREST, Ewan; HUEZO, Maria Sarai Gonzalez; CABRERA, Araceli Bravo; PEREZ-HERNANDEZ, Jose Luis; GUTIERREZ, Oscar Morales; KULKARNI, Anand V.; SHARMA, Mithun; SARIN, Shiv Kumar; EAPEN, C. E.; GANDOTRA, Akash; GOEL, Ashish; BETTINGER, Dominik; DUSEJA, Ajay K.; SCHULTHEISS, Michael; ZAZUETA, Godolfino Miranda; RAMOS-PINEDA, Abraham; TAN, Hiang Keat; LIOU, Wei Lun; BARRADAS, Mauricio Castillo; TREEPRASERTSUK, Sombat; WEJNARUEMARN, Salisa; VELAZQUEZ, Rene Male; MADE, Lilian Torres; KAPPUS, Matthew R.; WEGERMANN, Kara; DANIELLE, Adebayo; KENNEDY, James; BIGGINS, Scott W.; FILIPEK, Natalia; KEAVENY, Andrew Paul; YUNG, Diana; TANDON, Puneeta; DAHIYA, Monica; DUARTE-ROJO, Andres; NEGRILLO, Ricardo Cabello; REDDY, K. Rajender Rajender; RAHEMATPURA, Suditi; SARAYA, Anoop; YEGURLA, Jatin; GUNDUZ, Feyza; ASLAN, Rahmi; YILDIRIM, Abdullah Emre; BARUTCU, Sezgin; ARORA, Anil; KUMAR, Ashish; VERNA, Elizabeth; TUDEHOPE, Fiona; MARCIANO, Sebastian; GADANO, Adrian; KARASU, Zeki; UYSAL, Alper; UCBILEK, Enver; KOSAY, Tolga; VELASCO, Jose Antonio Velarde-Ruiz; FELIX-TELLEZ, Francisco; ADANIR, Haydar; DINCER, Dinc; DHIMAN, Radhakrishna; ROY, Akash; FAISAL, Nabiha; ANAND, Anil Chandra; PRAHARAJ, Dibyalochan; GIBSON, Robert; PRUDENCE, Alexander; XIAN, Yongchao; ZHU, Chuanwu; WANG, Yingling; SU, Minghua; SU, Man; GAO, Yanhang; WANG, Xinrui; JIANG, Yongfang; PENG, Feng; ZHAO, Caiyan; WANG, Wang; WANG, Lei; YIN, Dedong; LIU, Mingquin; CAI, Yijing; WANG, Xiaozhong; GUO, Feng; ZHANG, Ningping; ZHANG, Wanqin; LI, Hai; DONG, Fuchen; ZHENG, Xin; LIU, Jing; TANG, Hong; YAN, Libo; XU, Bin; WEI, Linlin; GAO, Zhiliang; XU, Zhen; GALLARDO, Jacqueline Cordova; LIN, Minghua; GAO, Haibin; WU, Xiaoping; RAO, Qunfang; ZEKRY, Amany; CHEN, Jinjun; LI, Beiling; LIU, Chenghai; ZHANG, Yanyun; DOYLE, Adam; NGUYEN, Vi; CHU, Elsa; HU, Peng; DENG, Huan; RIORDAN, Stephen; MICHALCZUK, Matheus; MACQUILLAN, Gerry; LI, Jie; WANG, Jian; FARIAS, Alberto Q.; ZITELI, Patricia; PEREIRA, Gustavo; VICTOR, Livia; WONG, Yu Jun; HO, Wei Ling; ALEXOPOULOU, Alexandra; MANI, Iliana; BOBAT, Bilal; YASSER, Fouad; MOSTAFA, Alaa; HAKTANIYAN, Busra; BUSH, Brian J.; THACKER, Leroy R.; BAJAJ, Jasmohan S.