VERA DEMARCHI AIELLO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- A ecocardiografia no laboratorio cardiovascular: um guia para a pesquisa com animais(2014) ABDUCH, Maria Cristina Donadio; ASSAD, Renato Samy; MATHIAS JR, Wilson; AIELLO, Vera DemarchiThe feasibility and potential for the morphological and hemodynamic investigation of the heart has been increasing the use of the echocardiography in the research setting. Additionally, the development of new technologies, like the real time 3D echocardiography and speckle tracking, demands validation throughout experimental studies before being instituted in the clinical setting. This paper aims to provide information concerning the particularities of the echocardiographic examination in quadruped mammals, targeting the experimental research.
conferenceObject HYPERCHOLESTEROLEMIC DIET WORST LEFT VENTRICULAR FUNCTION DESPITE REDUCTION OF MMP-2 EVALUATED BY ECHOCARDIOGRAPHY IN AN EXPERIMENTAL RAT INFARCT MODEL(2014) DOURADO, P.; LANDIM, M. B. P.; CASELLA FILHO, A.; TSUTSUI, J. M.; ROEVER, L.; AIELLO, V. D.; MATHIAS JR., W.; LUZ, P. da; CHAGAS, A. C. P.- Repair of congenital heart disease with associated pulmonary hypertension in children: what are the minimal investigative procedures? Consensus statement from the Congenital Heart Disease and Pediatric Task Forces, Pulmonary Vascular Research Institute (PVRI)(2014) LOPES, Antonio Augusto; BARST, Robyn J.; HAWORTH, Sheila Glennis; RABINOVITCH, Marlene; DABBAGH, Maha Al; CERRO, Maria Jesus del; IVY, Dunbar; KASHOUR, Tarek; KUMAR, Krishna; HARIKRISHNAN, S.; D'ALTO, Michele; THOMAZ, Ana Maria; ZORZANELLI, Leina; AIELLO, Vera D.; MOCUMBI, Ana Olga; SANTANA, Maria Virginia T.; GALAL, Ahmed Nasser; BANJAR, Hanaa; TAMIMI, Omar; HEATH, Alexandra; FLORES, Patricia C.; DIAZ, Gabriel; SANDOVAL, Julio; KOTHARI, Shyam; MOLEDINA, Shahin; GONCALVES, Rilvani C.; BARRETO, Alessandra C.; BINOTTO, Maria Angelica; MAIA, Margarida; HABSHAN, Fahad Al; ADATIA, IanStandardization of the diagnostic routine for children with congenital heart disease associated with pulmonary arterial hypertension (PAH-CHD) is crucial, in particular since inappropriate assignment to repair of the cardiac lesions (e. g., surgical repair in patients with elevated pulmonary vascular resistance) may be detrimental and associated with poor outcomes. Thus, members of the Congenital Heart Disease and Pediatric Task Forces of the Pulmonary Vascular Research Institute decided to conduct a survey aimed at collecting expert opinion from different institutions in several countries, covering many aspects of the management of PAH-CHD, from clinical recognition to noninvasive and invasive diagnostic procedures and immediate postoperative support. In privileged communities, the vast majority of children with congenital cardiac shunts are now treated early in life, on the basis of noninvasive diagnostic evaluation, and have an uneventful postoperative course, with no residual PAH. However, a small percentage of patients (older at presentation, with extracardiac syndromes or absence of clinical features of increased pulmonary blood flow, thus suggesting elevated pulmonary vascular resistance) remain at a higher risk of complications and unfavorable outcomes. These patients need a more sophisticated diagnostic approach, including invasive procedures. The authors emphasize that decision making regarding operability is based not only on cardiac catheterization data but also on the complete diagnostic picture, which includes the clinical history, physical examination, and all aspects of noninvasive evaluation.
- Capillary Hemangiomatosis Like-Lesions in Lung Biopsies from Children With Congenital Heart Defects(2014) AIELLO, Vera Demarchi; THOMAZ, Ana Maria; POZZAN, Geanete; LOPES, Antonio AugustoThe morphological findings in the lung vessels of children with pulmonary arterial hypertension associated with uncorrected congenital cardiac shunts may be qualitatively and quantitatively assessed by lung biopsy in selected cases. Among 297 lung biopsies collected over a period of 11 years two cases were detected presenting the typical findings of pulmonary capillary hemangiomatosis, a rare disorder usually associated with pulmonary veno-occlusive disease. We report the clinical and histological findings and discuss about the impact of this unexpected and not-previously described associated lesion on the prognosis and on the therapeutic strategy in patients with pulmonary hypertension associated with congenital heart disease. Pediatr Pulmonol. 2014; 49:E82-E85. (c) 2013 Wiley Periodicals, Inc.
conferenceObject THE TRANSPULMONARY GRADIENT BUT NOT THE SYSTOLIC OR MEAN PULMONARY ARTERIAL PRESSURE CORRELATES WITH THE WALL THICKNESS OF PERIPHERAL PULMONARY ARTERIES AND VEINS IN PATIENTS WITH CHRONIC HEART FAILURE(2014) AIELLO, Vera D.; CAMPOS, Pompeu R.; ISSA, Victor; HONORATO, Ronaldo; FIORELLI, Alfredo I.; BOCCHI, Edimar A.