THIAGO FELIPE DOS SANTOS BARROS
Projetos de Pesquisa
Unidades Organizacionais
P IOT, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
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- COMPARATIVE STUDY OF MICROANASTOMOSIS WITH DISTINCT 10-0 NYLON SUTURES IN RATS(2016) SILVA, Ricardo Teixeira e; BARROS, Thiago Felipe Santos; CARVALHO, Jose Thome de; RIBEIRO, Andre Araujo; PIRES, Andre Fernandes; WEI, Teng HsiangObjective: The aim of this study is to compare micro-sutures commonly used in our midst. Methods: In this double-blind study, 30 Wistar rats were operated randomly divided into three groups matched according to the suture used (Nylon 10-0, 75micron, brands Microsuture (R), Polysuture (R) and Ethicon (R)). We analyzed the number of surgical nodes required, bleeding, surgical time and histological evaluation. Results: There was no significant difference between the amount of stitches of arterial suture per anastomosis. Surgical time was longer in Microsuture (R) group as compared to Polysuture (R) (p <= 0.05). Bleeding in Microsuture (R) group was higher when compared to the others (p < 0.01). In the histological analysis, the Microsuture (R) group showed a greater tendency to develop fibrosis and aneurysm in surgical site than the others (p < 0.01 and p <= 0,05, respectively). Similarly, the Ethicon (R) group showed less tendency to myointimal proliferation than the rest. (p = 0.025). Conclusion: The results confirm the relevance of the choice of surgical thread as an independent determining factor for the success of the procedure, besides serving as a rational subsidy for a better cost-benefit analysis.