FABIO HENRIQUE DE GOBBI PORTO
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
3 resultados
Resultados de Busca
Agora exibindo 1 - 3 de 3
- The missed missing hole(2012) PORTO, Fabio Henrique de Gobbi; SILVA, Mari-Nilva Maia da; DOMINGUES, Joao Roberto Sala; PORTO, Gislaine Cristina Lopes Machado; DAVAGNAMAN, Indran; NITRINI, RicardoAt times in clinical neurology, the identification of a subtle clinical or radiological sign can lead to prompt diagnosis of a very rare or difficult case. We report on a patient who presented with untreatable headache and unilateral ptosis. Computed tomography (CT) scan of the head did not reveal any structural cause. Magnetic resonance angiogram showed absence of left internal carotid artery, which was eventually confirmed by a catheter angiography. Reviewing the case, it emerged that a feature on the initial CT scan ""bone window"" would have confirmed the diagnosis, had it been searched for: the underdeveloped carotid canal, which is a consequence and a marker of internal carotid artery agenesis.
- Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings(2012) GALVÃO, Antonio Cézar Ribeiro; MACHADO-PORTO, Gislaine Cristina Lopes; PORTO, Fábio Henrique de Gobbi; LUCATO, Leandro Tavares; NITRINI, RicardoABSTRACT A 35-year-old, previously healthy man presented psychiatric symptoms lasting four years, receiving treatment with neuroleptics. One year later he evolved with gait disequilibrium. After a further six months, cognitive symptoms were characterized with rapid evolution to a profound demented state. MRI showed signal changes in cerebral white matter and very long-chain fatty acids were detected in blood.
- Motor Neuron Disease and Acquired Axonal Neuropathy Association in HIV Infection: Case Report and Update(2012) ORSINI, Marco; FREITAS, Marcos R. G. de; SILVA, Julio G.; SOHLER, Marzia P.; REIS, Carlos H. M.; CATHARINO, Antonio M. da Silva; OLIVEIRA, Acary B.; MACHADO, Sergio; NARDI, Antonio E.; SALEM, Peter; SZTAJNBOK, Flavio; LEITE, Marco A. A.; NASCIMENTO, Cristiane; DAVIDOVICH, Eduardo; PORTO, Fabio H. de Gobbi; CRUZ, Marcia W.; MENEZES, Sara L. S. de; ARIAS-CARRION, OscarBackground: A possible viral etiology has been documented in the genesis of motor neuron disorders and acquired peripheral neuropathies, mainly due to the vulnerability of peripheral nerves and the anterior horn to certain viruses. In recent years, several reports show association of HIV infection with Amyotrophic Lateral Sclerosis Syndrome, Motor Neuron Diseases and peripheral neuropathies. Objective: To report a case of an association between Motor Neuron Disease and Acquired Axonal neuropathy in HIV infection, and describe the findings of neurological examination, cerebrospinal fluid, neuroimaging and electrophysiology. Methods: The patient underwent neurological examination. General medical examinations were performed, including, specific neuromuscular tests, analysis of cerebrospinal fluid, muscle biopsy and imaging studies. Results and Discussion: The initial clinical presentation of our case was marked by cramps and fasciculations with posterior distal paresis and atrophy in the left arm. We found electromyography tracings with deficits in the anterior horn of the spinal cord and peripheral nerves. Dysphagia and release of primitive reflexes were also identified. At the same time, the patient was informed to be HIV positive with high viral load. He received antiretroviral therapy, with load control but with no clinical remission. Conclusion: Motor Neuron disorders and peripheral neuropathy may occur in association with HIV infection. However, a causal relationship remains uncertain. It is noteworthy that the antiretroviral regimen may be implicated in some cases.