CIBELE LARROSA GARZILLO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
12 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 12
conferenceObject Impact of chronic kidney disease on diabetic patients with stable coronary disease undergoing surgery, angioplasty or medical treatment in a ten-year follow-up(2018) BATISTA, D. V.; HUEB, W.; LINHARES FILHO, J. P. P.; SILVA, R. R.; LIMA, E. G.; REZENDE, P. C.; MARTINS, E. B.; GARZILLO, C. L.; AZEVEDO, D. F. C.; RAMIRES, J. A. F.; KALIL FILHO, R.conferenceObject Cost-effectiveness analysis of on-pump and off-pump coronary artery bypass grafting for patients with multivesselcoronary artery disease: a Markov model based on data from the MASS III trial(2018) SCUDELER, T. L.; HUEB, W.; SOAREZ, P. C. De; CAMPOLINA, A. G.; HUEB, A. C.; REZENDE, P. C.; LIMA, E. G.; GARZILLO, C. L.; RIBAS, F. F.; TAKIUTI, M. E.; RAMIRES, J. A. F.; KALIL FILHO, R.conferenceObject Impact of glycated hemoglobin in diabetic patients with coronary artery disease undergoing surgery, angioplasty or clinical treatment in a very long-term follow-up(2018) LINHARES FILHO, J. P. P.; HUEB, W.; BATISTA, D. V.; SILVA, R. R.; LIMA, E. G.; REZENDE, P. C.; MARTINS, E. B.; GARZILLO, C. L.; AZEVEDO, D. F. C.; RAMIRES, J. A. F.; KALIL FILHO, R.- Cost-effectiveness of on-pump and off-pump coronary artery bypass grafting for patients with coronary artery disease: Results from the MASS III trial(2018) SCUDELER, Thiago Luis; HUEB, Whady A.; FARKOUH, Michael E.; MARON, David J.; SOAREZ, Patricia Coelho de; CAMPOLINA, Alessandro Goncalves; TAKIUTI, Myrthes Emy; REZENDE, Paulo Cury; GODOY, Lucas Colombo; HUEB, Alexandre Ciapinina; LIMA, Eduardo Gomes; GARZILLO, Cibele Larroza; RAMIRES, Jose Antonio Franchini; KALIL FILHO, RobertoBackground: Recent trials have reported similar clinical outcomes between on-pump and off-pump coronary artery bypass graft (CABG). However, long-term cost-effectiveness of these strategies is unknown. Methods: A prespedfied economic study was performed based on the MASS Ill trial. Costs were estimated for all patients based on observed healthcare resource usage over a 5-year follow-up. Health state utilities were evaluated with the SF-6D questionnaire. Cost-effectiveness was assessed as cost per quality-adjusted life-year (QALY) gained using a Markov model. Probabilistic sensitivity analysis with the Monte-Carlo simulation and cost-effectiveness acceptability curve were used to address uncertainty. Results: Quality of life improved significantly in both groups during follow-up compared with baseline. At 5 years, when comparing on-pump and off-pump CABG groups, no differences were found in cumulative life-years (4.851 and 4.766 years, P = .319) and QALY gained (4.150 and 4.105 QALYs, P = .332). Mean cost in US dollars per patient during the trial did not differ significantly between the on-pump and off-pump groups ($5890.29 and $5674.75, respectively, P = .409). Over a lifetime horizon, the incremental cost-effectiveness ratio of on-pump versus off-pump CABG was $12,576 per QALY gained, which is above the suggested cost-effectiveness threshold range (from $3210 to 10,122). In the sensitivity analysis, the probability that on-pump CABG is cost-effective compared to off-pump surgery for a willingness-to-pay threshold of $3212 per QALY gained was <1%. For the $10,122 per QALY threshold, the same probability was 35%. Conclusion: This decision-analytic model suggests that on-pump CABG is not cost-effective when compared to off-pump CABG from a public health system perspective.
conferenceObject Cardiac Biomarkers Elevation After Myocardial Revascularization Predicts Cardiovascular Prognosis. Long-Term Follow-Up of Mass-V Study(2018) LINHARES FILHO, Jaime P.; HUEB, Whady; V, Daniel Batista; LIMA, Eduardo G.; SILVA, Rafael R.; REZENDE, Paulo C.; STRUNZ, Celia M.; MARTINS, Eduardo B.; GARZILLO, Cibele L.; AZEVEDO, Diogo F.; DALLAZEN, Anderson R.; RIBAS, Fernando F.; RAMIRES, Jose A.; KALIL FILHO, RobertoconferenceObject Role of myocardial edema assessed by cardiac magnetic resonance after revascularization procedures(2018) RIBAS, F. F.; REZENDE, P. C.; BOROS, G. A. B.; DALLAZEN, A. R.; NOMURA, C. H.; ROCHITTE, C. E.; MORAIS, T.; VILLA, A. V.; GARZILLO, C. L.; HUEB, W.; RAMIRES, J. A. F.; KALIL FILHO, R.conferenceObject Long-Term Analysis of Ventricular Function in Patients With Stable Coronary Disease Underwent On-Pump or Off-Pump Coronary Artery Bypass Graft in Mass III(2018) SILVA, Rafael R.; HUEB, Whady; LIMA, Eduardo G.; MARTINS, Eduardo B.; V, Daniel Batista; LINHARES FILHO, Jaime P.; REZENDE, Paulo C.; GARZILLO, Cibele L.; RAMIRES, Jose A.; KALIL FILHO, RobertoconferenceObject Late Gadolinium Enhancement After Myocardial Revascularization is an Independent Predictor of Mortality Long-Term Follow-Up of Mass-v Study(2018) LINHARES FILHO, Jaime P.; HUEB, Whady; LIMA, Eduardo G.; V, Daniel Batista; REZENDE, Paulo C.; MARTINS, Eduardo B.; GARZILLO, Cibele L.; RIBAS, Fernando F.; DALLAZEN, Anderson R.; AZEVEDO, Diogo F.; VILLA, Alexandre V.; NOMURA, Cesar H.; RAMIRES, Jose A.; KALIL FILHO, RobertoconferenceObject Impact of Glycated Hemoglobin in Diabetic Patients With Coronary Artery Disease Undergoing Surgery, Angioplasty or Clinical Treatment in a Very Long-Term Follow-Up(2018) V, Daniel Batista; HUEB, Whady; LINHARES FILHO, Jaime P.; RIBAS, Fernando F.; SILVA, Rafael R.; LIMA, Eduardo G.; DALLAZEN, Anderson R.; GARCIA, Rosa M.; REZENDE, Paulo C.; MARTINS, Eduardo B.; GARZILLO, Cibele L.; AZEVEDO, Diogo F.; SILVA, Expedito E.; RAMIRES, Jose A.; KALIL FILHO, RobertoconferenceObject Long-term analysis of ventricular functionin patients with stable coronary disease submitted to on-pump or off-pump coronary artery bypass graft in MASS III(2018) SILVA, R. R.; LIMA, E. G.; BATISTA, D. V.; LINHARES FILHO, J. P. P.; MARTINS, E. B.; REZENDE, P. C.; GARZILLO, C. L.; RIBAS, F. F.; HUEB, W.; RAMIRES, J. A. F.; KALIL FILHO, R.