Effects of Exercise Intensity on Cardiometabolic Parameters of Ovariectomized Obese Mice

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Tipo de produção
article
Data de publicação
2023
Título da Revista
ISSN da Revista
Título do Volume
Editora
GEORG THIEME VERLAG KG
Autores
DOS-SANTOS, Adriano
COSTA-SANTOS, Nicolas Da
MELLO-SILVA, Fernanda Queiroz de
PEREIRA, Abel de Assis
JESUS, Ney Roberto de
ANGELIS, Katia De
BERNARDES, Nathalia
CAPERUTO, Erico Chagas
Citação
INTERNATIONAL JOURNAL OF SPORTS MEDICINE, v.44, n.8, p.584-591, 2023
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
The aim of this study was to compare the effects of continuous-moderate vs. high-intensity interval aerobic training on cardiovascular and metabolic parameters in ovariectomized high-fat-fed mice. C57BL/6 female ovariectomized were divided into four groups (n=8): low-fat-fed sedentary (SLF); high-fat-fed sedentary (SHF); high-fat-fed moderate-intensity continuous trained (MICT-HF); and high-fat-fed high-intensity interval aerobic trained (HIIT-HF). The high-fat diet lasted 10 weeks. Ovariectomy was performed in the fourth week. The exercise training was carried out in the last four weeks of protocol. Fasting glycemia, oral glucose tolerance, arterial pressure, baroreflex sensitivity, and cardiovascular autonomic modulation were evaluated. Moderate-intensity continuous training prevented the increase in arterial pressure and promoted a reduction in HR at rest, associated with an improvement in the sympathovagal balance in MICT-HF vs. SHF. The high-intensity interval training reduced blood glucose and glucose intolerance in HIIT-HF vs. SHF and MICT-HF. In addition, it improved sympathovagal balance in HIIT-HF vs. SHF. Moderate-intensity continuous training was more effective in promoting cardiovascular benefits, while high-intensity interval training was more effective in promoting metabolic benefits.
Palavras-chave
menopause, obesity, exercise training, heart rate variability, high-fat diet, high-intensity interval training
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