Rubella Vaccination of Unknowingly Pregnant Women: The Sao Paulo Experience, 2001
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Citações na Scopus
23
Tipo de produção
article
Data de publicação
2011
Título da Revista
ISSN da Revista
Título do Volume
Editora
OXFORD UNIV PRESS INC
Autores
SATO, Helena K.
SANAJOTTA, Andrea Torres
MORAES, Jose Cassio
DUARTE, Geraldo
CERVI, Maria Celia
CURTI, Sueli P.
PANNUTI, Claudio Sergio
MILANEZ, Helaine
PESSOTO, Monica
Citação
JOURNAL OF INFECTIOUS DISEASES, v.204, suppl.2, p.S737-S744, 2011
Resumo
Background. Rubella vaccination is contraindicated during pregnancy. During mass immunization of women of childbearing age against rubella, women unknowingly pregnant may be vaccinated. To evaluate the effects of rubella vaccination during pregnancy, the Brazilian state of Sao Paulo conducted a follow-up study of pregnant women vaccinated during a rubella campaign in 2001. Methods. Women vaccinated during pregnancy were reported to a national surveillance system. In the state of Sao Paulo, follow-up of vaccinated women included household interviews. Serum samples from vaccinated women were tested for antirubella antibodies to classify susceptibility to rubella infection. Children born to susceptible mothers were tested for evidence of congenital rubella infection and evaluated for signs of congenital rubella syndrome. Results. The Sao Paulo State Health Department received 6473 notifications of women vaccinated during pregnancy. Serology performed for 5580 women identified 811 (15%) that were previously susceptible. Incidence of spontaneous abortion or stillbirth among previously susceptible vaccinated women was similar to women with prior immunity. Twenty-seven (4.7%) of 580 newborns tested had evidence of congenital rubella infection; none had congenital rubella syndrome. Conclusions. Mass rubella vaccination of women of childbearing age was not associated with adverse birth outcomes or congenital rubella syndrome among children born to women vaccinated during pregnancy.
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Referências
- Prevots DR, 2003, J INFECT DIS, V187, pS111, DOI 10.1086/368030
- Badilla X, 2007, PEDIATR INFECT DIS J, V26, P830, DOI 10.1097/INF.0b013e318124a9f4
- Minussi L, 2008, REPROD TOXICOL, V25, P120, DOI 10.1016/j.reprotox.2007.09.002
- Banatvala JE, 2004, LANCET, V363, P1127, DOI 10.1016/S0140-6736(04)15897-2
- BART SW, 1985, REV INFECT DIS, V7, pS95
- BOSMA TJ, 1995, J CLIN MICROBIOL, V33, P1075
- *CDCP, 1987, JAMA-J AM MED ASSOC, V258, P753
- CENTERS FOR DISEASE CONTROL AND PREVENTION, 2001, MMWR-MORBID MORTAL W, V50, P1
- Centers for Disease Control and Prevention (CDC), 2001, MMWR-MORBID MORTAL W, V50, P1117
- Cherry J. D., 1998, TXB PEDIAT INFECT DI
- deSouza VAUF, 1997, J MED VIROL, V52, P275
- ENDERS G, 1985, REV INFECT DIS, V7, pS103
- Figueiredo CA, 2008, J CLIN VIROL, V43, P343, DOI 10.1016/j.jcv.2008.07.015
- Hamkar R, 2006, VACCINE, V24, P3558, DOI 10.1016/j.vaccine.2006.02.001
- Hedman K., 1993, REV MED MICROBIOL, V4, P123, DOI 10.1097/00013542-199307000-00001
- Lanzieri T. M., 2007, Journal of Pediatric Infectious Diseases, V2, P15
- Plotkin SA, 2004, VACCINES, P707
- Reef SE, 2000, CLIN INFECT DIS, V31, P85, DOI 10.1086/313928
- SA GRS, 2009, J INFECT DIS S2, V204, pS722
- *SAO PAUL STAT HLT, 1998, IMM PROGR GUID
- *SAO PAUL STAT HLT, 2001, RUB VACC CAMP WOM 20
- *SAO PAUL STAT HLT, 2007, PERC LIV BIRTHS BORN
- SILVA M, 2003, REV SAUDE PUBL, V37, P693
- THOMAS HIJ, 1991, REV MED VIROL, V1, P41, DOI 10.1002/rmv.1980010109
- Tookey P A, 1991, CDR (Lond Engl Rev), V1, pR86
- VAHERI A, 1969, AM J DIS CHILD, V118, P243
- VIAL P, 1986, REV MED CHILE, V114, P445
- *WHO, 1999, GUID SURV CONG RUB S
- World Health Organization, 1992, ICD10 WHO