Benefits and adverses effects of testosterone therapy

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCOSTA, E. M. F.
dc.contributor.authorAMATO, L. G. L.
dc.contributor.authorSILVEIRA, L. F. G.
dc.date.accessioned2023-02-09T20:01:39Z
dc.date.available2023-02-09T20:01:39Z
dc.date.issued2017
dc.description.abstractTestosterone plays an essential role in several aspects of men’s health. The main indication for testosterone treatment is in men with a confirmed diagnosis of hypogonadism, signs of androgen deficiency, and low serum testosterone levels. Other possible indications include constitutional delay of growth and puberty, men with sexual dysfunction, female to male transgender persons, androgen deficiency in the aging male, hypogonadism secondary to drugs, and chronic illness. Common drug-related adverse events include increase in hematocrit, acne, breast tenderness, gynecomastia, and exogenous testosterone can lead to a state of transitory infertility. It is not recommended to begin testosterone replacement therapy in men with untreated severe obstructive sleep apnea or with benign prostatic hypertrophy. The effects of testosterone on lipid metabolism and cardiovascular risk remain uncertain. In each situation the testosterone replacement brings specific benefits but the overall goals of therapy are to establish and maintain secondary sexual characteristics, sexual function, sense of well-being, and to improve body composition, muscle mass and strength, bone mineral density, and quality of life. © Springer International Publishing Switzerland 2017.
dc.identifier.citationCosta, E. M. F.; Amato, L. G. L.; Silveira, L. F. G.. Benefits and adverses effects of testosterone therapy. In: . TESTOSTERONE: FROM BASIC TO CLINICAL ASPECTS: SPRINGER INTERNATIONAL PUBLISHING, 2017. p.253-269.
dc.identifier.doi10.1007/978-3-319-46086-4_13
dc.identifier.isbn9783319460864; 9783319460840
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/51245
dc.language.isoeng
dc.publisherSPRINGER INTERNATIONAL PUBLISHING
dc.relation.ispartofTESTOSTERONE: FROM BASIC TO CLINICAL ASPECTS
dc.rightsopenAccess
dc.rights.holderCopyright SPRINGER INTERNATIONAL PUBLISHING
dc.subjectAndrogen deficiency
dc.subjectDrug-related adverse effects
dc.subjectHypogonadism
dc.subjectTestosterone replacement benefits
dc.titleBenefits and adverses effects of testosterone therapy
dc.typebookPart
dc.type.categorybook chapter
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcELAINE MARIA FRADE COSTA
hcfmusp.contributor.author-fmusphcLORENA GUIMARAES LIMA AMATO
hcfmusp.contributor.author-fmusphcLETICIA FERREIRA GONTIJO SILVEIRA
hcfmusp.description.beginpage253
hcfmusp.description.endpage269
hcfmusp.origemSCOPUS
hcfmusp.origem.scopus2-s2.0-85032983033
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