GASTRIC NEUROENDOCRINE TUMOR: REVIEW AND UPDATE

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorDIAS, Andre Roncon
dc.contributor.authorAZEVEDO, Beatriz Camargo
dc.contributor.authorALBAN, Luciana Bastos Valente
dc.contributor.authorYAGI, Osmar Kenji
dc.contributor.authorRAMOS, Marcus Fernando Kodama Pertille
dc.contributor.authorJACOB, Carlos Eduardo
dc.contributor.authorBARCHI, Leandro Cardoso
dc.contributor.authorCECCONELLO, Ivan
dc.contributor.authorRIBEIRO-JR, Ulysses
dc.contributor.authorZILBERSTEIN, Bruno
dc.date.accessioned2017-10-31T14:43:41Z
dc.date.available2017-10-31T14:43:41Z
dc.date.issued2017
dc.description.abstractABSTRACT Introduction: The frequency of gastric neuroendocrine tumors is increasing. Reasons are the popularization of endoscopy and its technical refinements. Despite this, they are still poorly understood and have complex management. Aim: Update the knowledge on gastric neuroendocrine tumor and expose the future perspectives on the diagnosis and treatment of this disease. Method: Literature review using the following databases: Medline/PubMed, Cochrane Library and SciELO. Search terms were: gastric carcinoid, gastric neuroendocrine tumor, treatment. From the selected articles, 38 were included in this review. Results: Gastric neuroendocrine tumors are classified in four clinical types. Correct identification of the clinical type and histological grade is fundamental, since treatment varies accordingly and defines survival. Conclusion: Gastric neuroendocrine tumors comprise different subtypes with distinct management and prognosis. Correct identification allows for a tailored therapy. Further studies will clarify the diseases biology and improve its treatment.
dc.description.abstractRESUMO Introdução: A frequência de tumores neuroendócrinos gástricos está aumentando. As razões são a popularização da endoscopia e seus refinamentos técnicos. Apesar disso, os gástricos ainda são pouco compreendidos e têm manejo complexo. Objetivo: Atualizar os conhecimentos nos tumores neuroendócrinos gástricos e expor as perspectivas futuras no diagnóstico e tratamento. Método: Revisão da literatura utilizando as seguintes bases de dados: Medline/PubMed, Cochrane Library e SciELO. Os descritores da busca foram: carcinóide gástrico, tumor neuroendócrino gástrico, tratamento. Dos artigos selecionados, 38 foram incluídos nesta revisão. Resultados: Tumores neuroendócrinos gástricos são classificados em quatro tipos clínicos. A identificação correta do tipo clínico e grau histológico é fundamental, pois a conduta é variável e define a sobrevida. Conclusão: Tumor neuroendócrino gástrico possui diferentes subtipos com tratamento e prognóstico distintos. A identificação correta destes e seu entendimento permite o tratamento individualizado. Estudos futuros ajudarão a esclarecer a biologia desta doença e melhorar o tratamento.
dc.description.indexMEDLINE
dc.identifier.citationABCD-ARQUIVOS BRASILEIROS DE CIRURGIA DIGESTIVA-BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY, v.30, n.2, p.150-154, 2017
dc.identifier.doi10.1590/0102-6720201700020016
dc.identifier.eissn2317-6326
dc.identifier.issn0102-6720
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/22236
dc.language.isoeng
dc.publisherColégio Brasileiro de Cirurgia Digestiva
dc.relation.ispartofABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
dc.rightsopenAccess
dc.rights.holderCopyright Colégio Brasileiro de Cirurgia Digestiva
dc.subjectGastric carcinoid
dc.subjectGastric neuroendocrine tumor
dc.subjectTreatment, review
dc.subjectCarcinóide gástrico
dc.subjectTumor neuroendócrino gástrico
dc.subjectTratamento, revisão.
dc.subject.otherCARCINOID-TUMORS
dc.subject.otherGASTROENTEROPANCREATIC TUMORS
dc.subject.otherCELL HYPERPLASIA
dc.subject.otherCARNOYS SOLUTION
dc.subject.otherHYPERGASTRINEMIA
dc.subject.otherGUIDELINES
dc.subject.otherMANAGEMENT
dc.subject.otherOCTREOTIDE
dc.subject.otherDIAGNOSIS
dc.subject.otherCONSENSUS
dc.titleGASTRIC NEUROENDOCRINE TUMOR: REVIEW AND UPDATE
dc.title.alternativeTUMOR NEUROENDÓCRINO GÁSTRICO: REVISÃO E ATUALIZAÇÃO
dc.typearticle
dc.type.categoryreview
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.contributor.author-fmusphcANDRE RONCON DIAS
hcfmusp.contributor.author-fmusphcBEATRIZ CAMARGO AZEVEDO
hcfmusp.contributor.author-fmusphcLUCIANA BASTOS VALENTE ALBAN
hcfmusp.contributor.author-fmusphcOSMAR KENJI YAGI
hcfmusp.contributor.author-fmusphcMARCUS FERNANDO KODAMA PERTILLE RAMOS
hcfmusp.contributor.author-fmusphcCARLOS EDUARDO JACOB
hcfmusp.contributor.author-fmusphcLEANDRO CARDOSO BARCHI
hcfmusp.contributor.author-fmusphcIVAN CECCONELLO
hcfmusp.contributor.author-fmusphcULYSSES RIBEIRO JUNIOR
hcfmusp.contributor.author-fmusphcBRUNO ZILBERSTEIN
hcfmusp.description.beginpage150
hcfmusp.description.endpage154
hcfmusp.description.issue2
hcfmusp.description.volume30
hcfmusp.origemWOS
hcfmusp.origem.pubmed29257854
hcfmusp.origem.scieloSCIELO:S0102-67202017000200150
hcfmusp.origem.wosWOS:000416611600016
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