Endometriosis and its correlation with carcinoid tumor of the appendix: a systematic review

Nenhuma Miniatura disponível
Citações na Scopus
2
Tipo de produção
article
Data de publicação
2021
Título da Revista
ISSN da Revista
Título do Volume
Editora
EDIZIONI MINERVA MEDICA
Autores
VILLAESCUSA, Marina
AMARAL, Alexandre C.
BARBOSA, Rodrigo N.
Citação
MINERVA OBSTETRICS AND GYNECOLOGY, v.73, n.5, p.606-613, 2021
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
INTRODUCTION: The prevalence of appendiceal endometriosis ranges from 0.4% to 22%. The carcinoid tumor is the most common neoplasm of the appendix, with incidence ranging from 0.3% to 0.9%. Appendix lesions develop in up to 22% of women with deep infiltrative endometriosis. Even though these are most likely endometriosis, carcinoid tumors should always be considered. The aim of this review was to assess the prevalence of appendiceal carcinoid tumors and appendiceal endometriosis in patients undergoing gynecologic surgery', its association with endometriosis, and related symptoms. EVIDENCE ACQUISITION: We included retrospective and prospective studies that assessed women who underwent appendicectomy in the past 20 years for appendiceal endometriosis and/or appendix carcinoid tumor confirmed by histological analysis. Results were reported as relative and absolute frequencies. Due to the heterogeneity of included studies, a statistical analysis (meta-analysis) was not performed. EVIDENCE SYNTHESIS: The prevalence of appendiceal endometriosis was 15.2% in patients who underwent surgery for pelvic endometriosis and 11.4% i n those who underwent benign gynecological surgery. Conversely. carcinoid tumors of the appendix were present in 2.4% of endometriosis patients and 1.3% of other benign gynecological surgeries. CONCLUSIONS: The rates of carcinoid tumors in patients with endometriosis are the same as in the general population. Given the risk of a malignant appendiceal tumor, in all gynecological surgeries, especially those for endometriosis, the appendix should be inspected and removed if it has an abnormal appearance.
Palavras-chave
Endometriosis, Carcinoid tumor, Appendix
Referências
  1. Abrao MS, 2020, J MINIM INVAS GYN, V27, P15, DOI 10.1016/j.jmig.2019.05.007
  2. Abrao MS, 2017, SEMIN REPROD MED, V35, P65, DOI 10.1055/s-0036-1597307
  3. Abrao MS, 2010, FERTIL STERIL, V94, P1099, DOI 10.1016/j.fertnstert.2009.10.031
  4. Agarwala N, 2003, J AM ASSOC GYN LAP, V10, P166, DOI 10.1016/S1074-3804(05)60292-7
  5. Barut B, 2019, ULUS TRAVMA ACIL CER, V25, P510, DOI 10.5505/tjtes.2018.99569
  6. Bellelis P, 2010, REV ASSOC MED BRAS, V56, P467, DOI 10.1590/S0104-42302010000400022
  7. Berker B, 2005, J MINIM INVAS GYN, V12, P206, DOI 10.1016/j.jmig.2005.03.003
  8. Canis M, 1997, FERTIL STERIL, V67, P817
  9. Carr NJ, 2004, SEMIN DIAGN PATHOL, V21, P108, DOI 10.1053/j.semdp.2004.11.004
  10. Chadwick T, 2018, JMIG, V25
  11. Duke A, 2014, JMIG, V21, P159
  12. Dunselman GAJ, 2014, HUM REPROD, V29, P400, DOI 10.1093/humrep/det457
  13. Farzan N, 2019, JMIG, V26, P168
  14. Flyckt R, 2017, SEMIN REPROD MED, V35, P54, DOI 10.1055/s-0036-1597306
  15. Green J, 2012, J MINIM INVAS GYN, V19, P95
  16. Harkins G, 2015, JMIG, V22
  17. Harris RS, 2001, J AM ASSOC GYN LAP, V8, P536, DOI 10.1016/S1074-3804(05)60617-2
  18. Hatch QM, 2018, CLIN COLON RECT SURG, V31, P278, DOI 10.1055/s-0038-1642051
  19. Hendricks R, 2019, JMIG, V26, P114
  20. Jocko JA, 2013, J OBSTET GYNAECOL CA, V35, P44, DOI 10.1016/S1701-2163(15)31047-1
  21. Koninckx PR, 2012, FERTIL STERIL, V98, P564, DOI 10.1016/j.fertnstert.2012.07.1061
  22. Lee JH, 2011, AM J OBSTET GYNECOL, V204, DOI 10.1016/j.ajog.2010.08.042
  23. Liu L, 2019, J MINIM INVAS GYN, V26, P185
  24. Luo DH, 2018, STAT METHODS MED RES, V27, P1785, DOI 10.1177/0962280216669183
  25. Nezhat C, 2009, JSLS-J SOC LAPAROEND, V13, P14
  26. Nikou A, 2019, J MINIM INVAS GYN, V26, P174
  27. Mota ILP, 2015, JSLS-J SOC LAPAROEND, V19, DOI 10.4293/JSLS.2015.00028
  28. Peters A, 2018, CURR OPIN OBSTET GYN, V30, P237, DOI 10.1097/GCO.0000000000000466
  29. Ross WT, 2020, J MINIM INVAS GYN, V27, P1531, DOI 10.1016/j.jmig.2020.01.009
  30. Shavell VI, 2011, GYNECOL OBSTET INVES, V71, P189, DOI 10.1159/000317270
  31. Wie HJ, 2008, AUST NZ J OBSTET GYN, V48, P107, DOI 10.1111/j.1479-828X.2007.00811.x