Psychological treatments for people with epilepsy
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Citações na Scopus
14
Tipo de produção
article
Data de publicação
2020
Título da Revista
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Editora
JOHN WILEY AND SONS LTD
Autores
MICHAELIS, R.
TANG, V.
NEVITT, S.J.
WAGNER, J.L.
MODI, A.C.
JR, W.C. LaFrance
GOLDSTEIN, L.H.
GANDY, M.
BRESNAHAN, R.
Citação
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, v.2020, n.8, article ID CD012081, p, 2020
Resumo
Background: Given the significant impact epilepsy may have on the health-related quality of life (HRQOL) of individuals with epilepsy and their families, there is increasing clinical interest in evidence-based psychological treatments, aimed at enhancing psychological and seizure-related outcomes for this group. This is an updated version of the original Cochrane Review published in Issue 10, 2017. Objectives: To assess the impact of psychological treatments for people with epilepsy on HRQOL outcomes. Search methods: For this update, we searched the following databases on 12 August 2019, without language restrictions: Cochrane Register of Studies (CRS Web), which includes randomized or quasi-randomized controlled trials from the Specialized Registers of Cochrane Review Groups including Epilepsy, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (Ovid, 1946 to 09 August 2019), and PsycINFO (EBSCOhost, 1887 onwards), and from PubMed, Embase, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform (ICTRP). We screened the references from included studies and relevant reviews, and contacted researchers in the field for unpublished studies. Selection criteria: We considered randomized controlled trials (RCTs) and quasi-RCTs for this review. HRQOL was the main outcome. For the operational definition of 'psychological treatments', we included a broad range of skills-based psychological treatments and education-only interventions designed to improve HRQOL, seizure frequency and severity, as well as psychiatric and behavioral health comorbidities for adults and children with epilepsy. These psychological treatments were compared to treatment as usual (TAU), an active control group (such as social support group), or antidepressant pharmacotherapy. Data collection and analysis: We used standard methodological procedures expected by Cochrane. Main results: We included 36 completed RCTs, with a total of 3526 participants. Of these studies, 27 investigated skills-based psychological interventions. The remaining nine studies were education-only interventions. Six studies investigated interventions for children and adolescents, three studies investigated interventions for adolescents and adults, and the remaining studies investigated interventions for adults. Based on satisfactory clinical and methodological homogeneity, we pooled data from 11 studies (643 participants) that used the Quality of Life in Epilepsy-31 (QOLIE-31) or other QOLIE inventories (such as QOLIE-89 or QOLIE-31-P) convertible to QOLIE-31. We found significant mean changes for the QOLIE-31 total score and six subscales (emotional well-being, energy and fatigue, overall QoL, seizure worry, medication effects, and cognitive functioning). The mean changes in the QOLIE-31 total score (mean improvement of 5.23 points, 95% CI 3.02 to 7.44; P < 0.001), and the overall QoL score (mean improvement of 5.95 points, 95% CI 3.05 to 8.85; P < 0.001) exceeded the threshold of minimally important change (MIC: total score: 4.73 points; QoL score: 5.22 points), indicating a clinically meaningful postintervention improvement in HRQOL. We downgraded the certainty of the evidence provided by the meta-analysis due to serious risks of bias in some of the included studies. Consequently, these results provided moderate-certainty evidence that psychological treatments for adults with epilepsy may enhance overall HRQOL. Authors' conclusions: Implications for practice: Skills-based psychological interventions improve HRQOL in adults and adolescents with epilepsy. Adjunctive use of skills-based psychological treatments for adults and adolescents with epilepsy may provide additional benefits in HRQOL when these are incorporated into patient-centered management. We judge the evidence to be of moderate certainty. Implications for research: Investigators should strictly adhere to the CONSORT guidelines to improve the quality of reporting on their interventions. A thorough description of intervention protocols is necessary to ensure reproducibility. When examining the effectiveness of psychological treatments for people with epilepsy, the use of standardized HRQOL inventories, such as the Quality of Life in Epilepsy Inventories (QOLIE-31, QOLIE-31-P, and QOLIE-89) would increase comparability. Unfortunately, there is a critical gap in pediatric RCTs and RCTs including people with epilepsy and intellectual disabilities. Finally, in order to increase the overall quality of RCT study designs, adequate randomization with allocation concealment and blinded outcome assessment should be pursued. As attrition is often high in research that requires active participation, an intention-to-treat analysis should be carried out. Treatment fidelity and treatment competence should also be assessed. These important dimensions, which are related to 'Risk of bias' assessment, should always be reported. Copyright © 2020 The Cochrane Collaboration.
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Referências
- Au, A., Chan, F., Li, K., Leung, P., Li, P., Chan, J., Cognitive-behavioral group treatment program for adults with epilepsy in Hong Kong (2003) Epilepsy & Behavior, 4 (4), pp. 441-446. , [PMID, x-wiley/crsRef/6944701 12899867
- Beretta, S., Beghi, E., Messina, P., Gerardi, F., Pescini, F., La Licata, A., Comprehensive educational plan for patients with epilepsy and comorbidity (EDU-COM): a pragmatic randomised trial (2014) Journal of Neurology, Neurosurgery, and Psychiatry, 85 (8), pp. 889-894. , [0022-3050] [PMID, x-wiley/crsRef/6944703 24403284
- Brown, D.M., Mahlberg, N., Pohl, D., Timmons, B.W., Bray, S.R., Streiner, D.L., Can behavioral strategies increase physical activity and influence depressive symptoms and quality of life among children with epilepsy? Results of a randomized controlled trial (2019) Epilepsy & Behavior, 94, pp. 158-166. , [] [PMID, x-wiley/crsRef/14417464 dx.doi.org/10.1016/j.yebeh.2019.03.011 30939411
- Caller, T., Ferguson, R., Roth, R., Secore, K., Alexandre, F., Zhao, W., Self-management (HOBSCOTCH) improves cognition and quality of life in epilepsy: a randomised controlled trial (2016) Neurology, 86 (16), p. 005. , x-wiley/crsRef/6944705
- Caller, T.A., Ferguson, R.J., Roth, R.M., Secore, K.L., Alexandre, F.P., Zhao, W., A cognitive behavioral intervention (HOBSCOTCH) improves quality of life and attention in epilepsy (2016) Epilepsy & Behavior, 57, pp. 111-117. , [PMID, x-wiley/crsRef/14417465 26943948
- Caller, T.A., Secore, K.L., Ferguson, R.J., Roth, R.M., Alexandre, F.P., Kleen, J., A randomized controlled trial of hobscotch: a self-management intervention for cognitive impairment in epilepsy (2015) Epilepsy Currents, 15, p. 39. , x-wiley/crsRef/14417466
- Jobst, B., Caller, T., Ferguson, R., Roth, R., Secore, K., Alexandre, F., A cognitive-behavioral intervention (Hobscotch) improves quality of life and attention in epilepsy: a pilot study (2016) Epilepsia, 57, p. 28. , x-wiley/crsRef/14417467
- Streltzov, N., Schimdt, S., Zhao, W., Roth, R., Secore, K., Schommer, L., Improving quality of life in epilepsy: replication and generalizability of an epilepsy self-management and cognitive training program (HOBSCOTCH) (2017) Neurology, 88 (16), p. 003. , x-wiley/crsRef/14417468
- Chaytor, N., Ciechanowski, P., Miller, J.W., Fraser, R., Russo, J., Unutzer, J., Long-term outcomes from the PEARLS randomised trial for the treatment of depression in patients with epilepsy (2011) Epilepsy & Behavior, 20 (3), pp. 545-549. , [] [PMID, x-wiley/crsRef/6944708 21333607
- Ciechanowski, P., Chaytor, N., Miller, J., Fraser, R., Russo, J., Unutzer, J., PEARLS depression treatment for individuals with epilepsy: a randomised controlled trial (2010) Epilepsy & Behavior, 19 (3), pp. 225-231. , [] [PMID, x-wiley/crsRef/6944709 20609631
- DiIorio, C., Bamps, Y., Walker, E., Results of a randomised controlled trial evaluating WebEase, an online self-management program (2011) Epilepsy Currents, 11, p. 358. , x-wiley/crsRef/6944711
- Pfäfflin, M., Schmitz, B., May, T.W., Efficacy of the epilepsy nurse: results of a randomised controlled study (2016) Epilepsia, 57 (7), pp. 1190-1198. , [, Print 1528-1167, Electronic] [PMID, x-wiley/crsRef/6944741 27265887
- Pramuka, M., Hendrickson, R., Zinski, A., Van Cott, A.C., A psychosocial self-management program for epilepsy: a randomised pilot study in adults (2007) Epilepsy & Behavior, 11 (4), pp. 533-545. , [PMID, x-wiley/crsRef/6944743 17904909
- Rau, J., May, T.W., Pfäfflin, M., Heubrock, D., Petermann, F., Education of children with epilepsy and their parents by the modular education program epilepsy for families (FAMOSES)--results of an evaluation study (2006) Rehabilitation, 45 (1), pp. 27-39. , [PMID, x-wiley/crsRef/6944745 16468111
- Kralj-Hans, I., Goldstein, L.H., Noble, A.J., Landau, S., Magill, N., McCrone, P., Self-Management education for adults with poorly controlled epILEpsy (SMILE (UK)): a randomised controlled trial protocol (2014) BMC Neurology, 14, p. 69. , [] [PMID, x-wiley/crsRef/14417487 dx.doi.org/10.1186/1471-2377-14-69 24694207
- Ridsdale, L., Kralj-Hans, I., Noble, A., Landau, S., McCrone, P., Morgan, M., Self-management education for epilepsy: an RCT protocol (2014) Journal of Neurology, Neurosurgery and Psychiatry, 85 (10), pp. A20-A21. , x-wiley/crsRef/14417488 dx.doi.org/10.1136/jnnp-2014-309236.76
- Ridsdale, L., McKinlay, A., Wojewodka, G., Robinson, E.J., Mosweu, I., Feehan, S.J., Self-Management education for adults with poorly controlled epILEpsy [SMILE (UK)]: a randomised controlled trial (2018) Health Technology Assessment (Winchester, England), 22 (21), pp. 1-142. , [] [PMID, x-wiley/crsRef/14417489 dx.doi.org/10.3310/hta22210 29717699
- Ridsdale, L., Wojewodka, G., Robinson, E., Landau, S., Noble, A.J., Morgan, M., Self-management education for adults with poorly controlled epilepsy (SMILE-UK) (2017) Epilepsia, 58, p. S19. , x-wiley/crsRef/14417490
- Ridsdale, L., Self-management education for adults with poorly controlled epilepsy: the SMILE trial (2015) European Journal of Neurology, 22, p. 118. , x-wiley/crsRef/14417491 dx.doi.org/10.1111/ene.12806
- Ring, H., Howlett, J., Pennington, M., Smith, C., Redley, M., Murphy, C., Training nurses in a competency framework to support adults with epilepsy and intellectual disability: the EpAID cluster RCT (2018) Health Technology Assessment, 22 (10), pp. 1-104. , [PMID, x-wiley/crsRef/14417493 29457585
- Sajatovic, M., Tatsuoka, C., Welter, E., Perzynski, A.T., Colon-Zimmermann, K., Van Doren, J.R., Targeted self-management of epilepsy and mental illness for individuals with epilepsy and psychiatric comorbidity (2016) Epilepsy & Behavior, 64 (Pt A), pp. 152-159. , [] [PMID, x-wiley/crsRef/14417495 dx.doi.org/10.1016/j.yebeh.2016.08.012 27743547
- McLaughlin, D.P., McFarland, K., A randomised trial of a group based cognitive behavior therapy program for older adults with epilepsy: the impact on seizure frequency, depression and psychosocial well-being (2011) Journal of Behavioral Medicine, 34 (3), pp. 201-207. , [PMID, x-wiley/crsRef/6944772 20927577
- Sajatovic, M., Colon-Zimmermann, K., Kahriman, M., Fuentes-Casiano, E., Burant, C., Aebi, M.E., One-year follow-up of a remotely delivered epilepsy self-management program in high-risk people with epilepsy (2019) Epilepsy & Behavior, 96, pp. 237-243. , [] [PMID, x-wiley/crsRef/14417497 dx.doi.org/10.1016/j.yebeh.2019.04.034 31126825
- Sajatovic, M., Colon-Zimmermann, K., Kahriman, M., Fuentes-Casiano, E., Liu, H., Tatsuoka, C., A 6-month prospective randomized controlled trial of remotely delivered group format epilepsy self-management versus waitlist control for high-risk people with epilepsy (2018) Epilepsia, 59 (9), pp. 1684-1695. , [] [PMID, x-wiley/crsRef/14417498 dx.doi.org/10.1111/epi.14527 30098003
- Schröder, J., Brückner, K., Fischer, A., Lindenau, M., Köther, U., Vettorazzi, E., Efficacy of a psychological online intervention for depression in people with epilepsy: a randomised controlled trial (2014) Epilepsia, 55 (12), pp. 2069-2076. , [PMID, x-wiley/crsRef/6944747 25410633
- Tang, V., Kwan, P., Poon, W.S., Mindfulness-based psychological treatment and social support intervention for drug-resistant epilepsy: a randomised, assessor-blinded, controlled trial (2013) Epilepsia, 54, p. 324. , x-wiley/crsRef/6944749
- Tang, V., Poon, W.S., Kwan, P., Mindfulness-based therapy for drug-resistant epilepsy: an assessor-blinded randomised trial (2015) Neurology, 85 (13), pp. 1100-1107. , [PMID, x-wiley/crsRef/6944750 26333801
- Thompson, N.J., Patel, A., Selwa, L.M., Begley, C.E., Fraser, R.T., Johnson, E., Preventing depression in epilepsy: Project Uplift (2013) Epilepsy Currents, 13, p. 489. , x-wiley/crsRef/14417499
- Thompson, N.J., Walker, E.R., Obolensky, N., Winning, A., Barmon, C., Diiorio, C., Distance delivery of mindfulness-based cognitive therapy for depression: project UPLIFT (2010) Epilepsy & Behavior, 19 (3), pp. 247-254. , [] [PMID, x-wiley/crsRef/6944752 20851055
- Turan Gurhopur, F.D., Isler Dalgic, A., The effect of a modular education program for children with epilepsy and their parents on disease management (2018) Epilepsy & Behavior, 78, pp. 210-218. , [] [PMID, x-wiley/crsRef/14417501 dx.doi.org/10.1016/j.yebeh.2017.07.048 29203274
- Yadegary, M.A., Maemodan, F.G., Nayeri, N.D., Ghanjekhanlo, A., The effect of self-management training on health-related quality of life in patients with epilepsy (2015) Epilepsy & Behavior, 50, pp. 108-112. , [] [PMID, x-wiley/crsRef/6944754 26232570
- Albert, D.V., Moreland, J.J., Salvator, A., Moore-Clingenpeel, M., Haridas, B., Cole, J.W., Seizure action plans for pediatric patients with epilepsy: a randomized controlled trial (2019) Journal of Child Neurology, 34 (11), pp. 666-673. , [] [PMID, x-wiley/crsRef/14417503 dx.doi.org/10.1177/0883073819846810 31156013
- Mills, N., Bachmann, M.O., Harvey, I., Hine, I., McGowan, M., Effect of a primary-care-based epilepsy specialist nurse service on quality of care from the patients' perspective: quasi-experimental evaluation (1999) Seizure, 8 (1), pp. 1-7. , [] [PMID, x-wiley/crsRef/14417512 10091840
- Aliasgharpour, M., Dehgahn Nayeri, N., Yadegary, M.A., Haghani, H., Effects of an educational program on self-management in patients with epilepsy (2013) Seizure, 22 (1), pp. 48-52. , [PMID, x-wiley/crsRef/6944756 23122512
- Cazares Miranda, V., Solis Flores, L., Granados Rangel, M.G., Mendoza Hernandez, F., Lopez Alvarenga, J.C., Benefits of personalised nurse counselling in neurological patients (2017) Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica, 46, pp. 18-25. , x-wiley/crsRef/14417505
- Chadi, N., Kaufman, M., Weisbaum, E., Malboeuf-Hurtubise, C., Kohut, S.A., Locke, J., Comparison of an in-person vs. ehealth mindfulness meditation-based intervention for adolescents with chronic medical conditions: a mixed methods study (2018) Journal of Adolescent Health, 62 (2), p. S122. , x-wiley/crsRef/14417507
- Dahl, J., Brorson, L.O., Melin, L., Effects of a broad-spectrum behavioral medicine treatment program on children with refractory epileptic seizures: an 8-year follow-up (1992) Epilepsia, 33 (1), pp. 98-102. , [] [PMID, x-wiley/crsRef/14417508 1733765
- Dahl, J., Melin, L., Brorson, L.O., Schollin, J., Effects of a broad-spectrum behavior modification treatment program on children with refractory epileptic seizures (1985) Epilepsia, 26 (4), pp. 303-309. , [PMID, x-wiley/crsRef/6944758 4006888
- Dash, D., Sebastian, T.M., Aggarwal, M., Tripathi, M., Impact of health education on drug adherence and self-care in people with epilepsy with low education (2015) Epilepsy & Behavior, 44, pp. 213-217. , [PMID, x-wiley/crsRef/6944762 25768712
- Davis, G.R., Donovan, D.M., Temkin, N.R., Cognitive-behavioral treatment of depressed affect among epileptics: preliminary findings (1984) Journal of Clinical Psychology, 40 (4), pp. 930-935. , Armstrong HE Jr,, [PMID, x-wiley/crsRef/6944764 6434595
- DiIorio, C., Reisinger, E.L., Yeager, K.A., McCarty, F., A telephone-based self-management program for people with epilepsy (2009) Epilepsy & Behavior, 14 (1), pp. 232-236. , [PMID, x-wiley/crsRef/6944766 19010447
- Eshiet, U., Okonta, J., Ukwe, C., The efficacy of a pharmacist implemented educational treatment programme for people with epilepsy: a report of a randomised controlled trial (2019) Seizure, 69, pp. 147-153. , [, Print 1532-2688, Electronic] [PMID, x-wiley/crsRef/14417510 31048271
- Helgeson, D.C., Mittan, R., Tan, S.Y., Chayasirisobhon, S., Sepulveda Epilepsy Education: the efficacy of a psychoeducational treatment program in treating medical and psychosocial aspects of epilepsy (1990) Epilepsia, 31 (1), pp. 75-82. , [PMID, x-wiley/crsRef/6944768 2303015
- Modi, A.C., Mann, K.A., Urso, L., Peugh, J., Preliminary feasibility and efficacy of text messaging and application-based adherence interventions in adolescents with epilepsy (2016) Epilepsy & Behavior, 63, pp. 46-49. , [] [PMID, x-wiley/crsRef/14417514 dx.doi.org/10.1016/j.yebeh.2016.07.036 27565437
- Li, J., Wang, X., Meng, H., Zeng, K., Quan, F., Liu, F., Systemic family therapy of comorbidity of anxiety and depression with epilepsy in adolescents (2016) Psychiatry Investigation, 13 (3), pp. 305-310. , [PMID, x-wiley/crsRef/6944770 27247596
- Modi, A.C., Guilfoyle, S.M., Mann, K.A., Rausch, J.R., A pilot randomised controlled clinical trial to improve antiepileptic drug adherence in young children with epilepsy (2016) Epilepsia, 57 (3), pp. e69-75. , [0013-9580] [PMID, x-wiley/crsRef/14417516 26693964
- Mohamadpour, S., Tajikzadeh, F., Aflakseir, A., The efficacy of mindfulness-based cognitive therapy on self-efficacy and anxiety among epileptic patients (2017) Archives of Neuroscience, 4 (2). , x-wiley/crsRef/14417518
- Olley, B.O., Osinowo, H.O., Brieger, W.R., Psycho-educational therapy among Nigerian adult patients with epilepsy: a controlled outcome study (2001) Patient Education and Counseling, 42 (1), pp. 25-33. , [PMID, x-wiley/crsRef/6944776 11080603
- Peterson, G.M., McLean, S., Millingen, K.S., A randomised trial of strategies to improve patient compliance with anticonvulsant therapy (1984) Epilepsia, 25 (4), pp. 412-417. , [PMID, x-wiley/crsRef/6944778 6430689
- Hagemann, A., Pfäfflin, M., Nussbeck, F., May, T.W., The efficacy of an educational program for parents of children with epilepsy (FAMOSES): results of a controlled multicenter evaluation study ekvv.uni-bielefeld.de/blog/uniaktuell/resource/Poster2.pdf, , [Was bringt das Schulungsprogramm famoses den Eltern epilepsiekranker Kinder? Ergebnisse einer kontrollierten, multizentrischen Evaluationsstudie]., (accessed 3 May 2016)., x-wiley/crsRef/6944780
- Pfäfflin, M., Petermann, F., Rau, J., May, T.W., The psychoeducational program for children with epilepsy and their parents (FAMOSES): results of a controlled pilot study and a survey of parent satisfaction over a five-year period (2012) Epilepsy & Behavior, 25 (1), pp. 11-16. , [PMID, x-wiley/crsRef/6944781 22980075
- Ridsdale, L., Kwan, I., Cryer, C., Newly diagnosed epilepsy: can nurse specialists help? A randomised controlled trial. Epilepsy Care Evaluation Group (2000) Epilepsia, 41 (8), pp. 1014-1019. , [PMID, x-wiley/crsRef/6944783 10961629
- Davies, S., Heyman, I., Goodman, R., A population survey of mental health problems in children with epilepsy (2003) Developmental Medicine and Child Neurology, 45 (5), pp. 292-295. , [PMID, 12729141
- Tajrishi, M.P., Abbasi, S., Fard, T.N., Yousefi, S., Abadi, A.M., Kasmaei, H.D., Efficacy of attribution retraining on mental health of epileptic children (2015) Iranian Red Crescent Medical Journal, 17 (10). , x-wiley/crsRef/6944785
- Tan, S.Y., Bruni, J., Cognitive-behavior therapy with adult patients with epilepsy: a controlled outcome study (1986) Epilepsia, 27 (3), pp. 225-233. , [PMID, x-wiley/crsRef/6944787 3516668
- Thompson, N.J., Patel, A.H., Selwa, L.M., Stoll, S.C., Begley, C.E., Johnson, E.K., Expanding the efficacy of project UPLIFT: distance delivery of mindfulness-based depression prevention to people with epilepsy (2015) Journal of Consulting and Clinical Psychology, 83 (2), pp. 304-313. , [PMID, x-wiley/crsRef/6944789 25495361
- Yoo, H., Development and evaluation of the Empowering A Self-Efficacy (EASE) program for children with epilepsy (2015) Journal of Korean Academy of Nursing, 45 (1), pp. 54-63. , Kim H-S.,] [] [PMID, x-wiley/crsRef/14417520 dx.doi.org/10.4040/jkan.2015.45.1.54 25743734
- Bennett, S., Heyman, I., Coughtrey, A., Simmonds, J., Varadkar, S., Stephenson, T., Guided self-help interventions for mental health disorders in children with neurological conditions: study protocol for a pilot randomised controlled trial (2016) Trials [Electronic Resource], 17 (1), p. 532. , [] [PMID, x-wiley/crsRef/14417522 27809925
- Singh, G., Sharma, S., Bansal, R.K., Setia, R.K., Sharma, S., Bansal, N., A home-based, primary-care model for epilepsy care in India: basis and design (2019) Epilepsia Open, 4 (2), pp. 264-274. , [] [PMID, x-wiley/crsRef/14417524 dx.doi.org/10.1002/epi4.12311 31168493
- Alper, K., Schwartz, K.A., Kolts, R.L., Khan, A., Seizure incidence in psychopharmacological clinical trials: an analysis of Food and Drug Administration (FDA) summary basis of approval reports (2007) Biological Psychiatry, 62 (4), pp. 345-354. , [PMID, 17223086
- Baca, C., Vickrey, B., Caplan, R., Vassar, S., Berg, A., Psychiatric and medical comorbidity and quality of life outcomes in childhood-onset epilepsy (2011) Pediatrics, 128 (6), pp. e1532-e1543. , [PMID, 22123895
- Baldwin, S.A., Imel, Z., Therapist effects (2013) Handbook of Psychotherapy and Behavioral Change, pp. 258-297. , Lambert MJ, editors(s)., New York, Wiley
- Benavente-Aguilar, I., Morales-Blanquez, C., Rubio, E.A., Rey, J.M., Quality of life of adolescents suffering from epilepsy living in the community (2004) Journal of Paediatrics and Child Health, 40 (3), pp. 110-113. , [PMID, 15009574
- Devinsky, O., Westbrook, L., Cramer, J., Glassman, M., Perrine, K., Camfield, C., Risk factors for poor health-related quality of life in adolescents with epilepsy (1999) Epilepsia, 40 (12), pp. 1715-1720. , [PMID, 10612334
- Borghs, S., de la Loge, C., Cramer, J.A., Defining minimally important change in QOLIE-31 scores: estimates from three placebo-controlled lacosamide trials in patients with partial-onset seizures (2012) Epilepsy & Behavior, 23 (3), pp. 230-234. , [PMID, 22341962
- Boutron, I., Moher, D., Altman, D.G., Schulz, K.F., Ravaud, P., Methods and processes of the CONSORT Group: example of an extension for trials assessing nonpharmacologic treatments (2008) Annals of Internal Medicine, 148 (4), pp. W60-W66. , [PMID, 18283201
- Brown, I., Sheeran, P., Reuber, M., Enhancing antiepileptic drug adherence: a randomised controlled trial (2009) Epilepsy & Behavior, 16 (4), pp. 634-639. , [PMID, 19864187
- Camfield, C., Breau, L., Camfield, P., Impact of pediatric epilepsy on the family: a new scale for clinical and research use (2001) Epilepsia, 42 (1), pp. 104-112. , [PMID, 11207793
- Epilepsy in adults and access to care — United States, 2010 MMWR. Morbidity and Mortality Weekly Report, 61 (45), pp. 909-913. , 2012 Nov 16;, [PMID, 23151949
- Chang, Y.T., Chen, P.C., Tsai, I.J., Sung, F.C., Chin, Z.N., Kuo, H.T., Bidirectional relation between schizophrenia and epilepsy: a population-based retrospective cohort study (2011) Epilepsia, 52 (11), pp. 2036-2042. , [PMID, 21929680
- Cohen, J., (1988) Statistical Power Analysis for the Behavioral Sciences, , Lawrence Erlbaum Associates
- Crail-Melendez, D., Herrera-Melo, A., Martinez-Juarez, I.E., Ramirez-Bermudez, J., Cognitive-behavioral therapy for depression in patients with temporal lobe epilepsy: a pilot study (2012) Epilepsy & Behavior, 23 (1), pp. 52-56. , [PMID, 22154515
- Cramer, J.A., Westbrook, L.E., Devinsky, O., Perrine, K., Glassman, M.B., Camfield, C., Development of the Quality of Life in Epilepsy Inventory for Adolescents: the QOLIE-AD-48 (1999) Epilepsia, 40 (8), pp. 1114-1121. , [PMID, 10448825
- Cramer, J.A., Van Hammée, G., Maintenance of improvement in health-related quality of life during long-term treatment with levetiracetam (2003) Epilepsy & Behavior, 4 (2), pp. 118-123. , [PMID, doi.org/10.1016/S1525-5050(03)00004-0 12697135
- DiIorio, C., Faherty, B., Manteuffel, B., Self-efficacy and social support in self-management of epilepsy (1992) Western Journal of Nursing Research, 14 (3), pp. 292-307. , [PMID, 1615646
- Cull, C., (1997) The Clinical Psychologist's Handbook of Epilepsy: Assessment and Management, , Goldstein LH (eds)., Routledge Press
- Ekinci, O., Titus, J.B., Rodopman, A.A., Berkem, M., Trevathan, E., Depression and anxiety in children and adolescents with epilepsy: prevalence, risk factors, and treatment (2009) Epilepsy & Behavior, 14 (1), pp. 8-18. , [PMID, 18804186
- Eklund, A., Nichols, T.E., Knutsson, H., Cluster failure: why fMRI inferences for spatial extent have inflated false-positive rates (2016) Proceedings of the National Academy of Sciences of the United States of America, 113 (28), pp. 7900-7905. , [PMID, 27357684
- Elsas, S.M., Gregory, W.L., White, G., Navarro, G., Salinsky, M.C., Andrews, D.J., Aura interruption: the Andrews/Reiter behavioral intervention may reduce seizures and improve quality of life - a pilot trial (2011) Epilepsy & Behavior, 22 (4), pp. 765-772. , [PMID, 22056814
- Escoffery, C., Bamps, Y., Stoll, S., Shegog, R., Buelow, J., Development of the Adult Epilepsy Self-Management Measurement Instrument (AESMMI) (2015) Epilepsy & Behavior, 50, pp. 172-183. , LaFrance WC Jr,,] [PMID, 26303037
- Escoffery, C., Bamps, Y., Stoll, S., Shegog, R., Buelow, J., Factor analyses of an Adult Epilepsy Self-Management Measurement Instrument (AESMMI) (2015) Epilepsy & Behavior, 50, pp. 184-189. , LaFrance WC Jr,,] [PMID, 26264465
- Ferro, M.A., Camfield, C.S., Levin, S.D., Smith, M.L., Wiebe, S., Zou, G., Trajectories of health-related quality of life in children with epilepsy: a cohort study (2013) Epilepsia, 54 (11), pp. 1889-1897. , [PMID, 26264465
- Fisher, R.S., Van Emde Boas, W., Blume, W., Elger, C., Genton, P., Lee, P., Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) (2005) Epilepsia, 46 (4), pp. 470-472. , [PMID, 15816939
- DiIorio, C., Bamps, Y., Walker, E.R., Escoffery, C., Results of a research study evaluating WebEase, an online epilepsy self-management program (2011) Epilepsy & Behavior, 22 (3), pp. 469-474. , [] [PMID, x-wiley/crsRef/6944712 21889413
- Fisher, R.S., Acevedo, C., Arzimanoglou, A., Bogacz, A., Cross, J.H., Elger, C.E., ILAE official report: a practical clinical definition of epilepsy (2014) Epilepsia, 55 (4), pp. 475-482. , [PMID, 24730690
- Fried, R., Fox, M.C., Carlton, R.M., Effect of diaphragmatic respiration with end-tidal CO2 biofeedback on respiration, EEG, and seizure frequency in idiopathic epilepsy (1990) Annals of the New York Academy of Sciences, 602, pp. 67-96. , [PMID, 2122789
- Gandy, M., Sharpe, L., Nicholson Perry, K., Psychosocial predictors of depression and anxiety in patients with epilepsy: a systematic review (2012) Journal of Affective Disorders, 140 (3), pp. 222-232. , [PMID, 22197509
- Gandy, M., Sharpe, L., Perry, K.N., Cognitive behavior therapy for depression in people with epilepsy: a systematic review (2013) Epilepsia, 54 (10), pp. 1725-1734. , [PMID, 24032437
- Gandy, M., Karin, E., Fogliati, V.J., McDonald, S., Titov, N., Dear, B.F., A feasibility trial of an Internet-delivered and transdiagnostic cognitive behavioral therapy treatment program for anxiety, depression and disability among adults with epilepsy (2016) Epilepsia, 57 (11), pp. 1887-1896. , [PMID, 27714788
- Gilbert, F., The burden of normality: from 'chronically ill' to 'symptom free'. New ethical challenges for deep brain stimulation postoperative treatment (2012) Journal of Medical Ethics, 38 (7), pp. 408-412. , [PMID, 22431560
- Gilliam, F., Optimizing health outcomes in active epilepsy (2002) Neurology, 58 (8), pp. S9-20. , [PMID, 11971128
- Gilliam, F.G., Fessler, A.J., Baker, G., Vahle, V., Carter, J., Attarian, H., Systematic screening allows reduction of adverse antiepileptic drug effects: a randomized trial (2004) Neurology, 62 (1), pp. 23-27. , [PMID, 14718691
- (2015) GRADEPro GDT, , Version (accessed prior to 24 August 2017). Hamilton (ON) McMaster University (developed by Evidence Prime),, gradepro.org
- Hesdorffer, D.C., Hauser, W.A., Annegers, J.F., Cascino, G., Major depression is a risk factor for seizures in older adults (2000) Annals of Neurology, 47 (2), pp. 246-249. , [PMID, 10665498
- Dorris, L., Broome, H., Wilson, M., Grant, C., Young, D., Baker, G., A randomized controlled trial of a manual-based psychosocial group intervention for young people with epilepsy [PIE] (2017) Epilepsy & Behavior, 72, pp. 89-98. , [] [PMID, x-wiley/crsRef/14417470 https://dx.doi.org/10.1016/j.yebeh.2017.04.007 28575774
- Hesdorffer, D.C., Hauser, W.A., Olafsson, E., Ludvigsson, P., Kjartansson, O., Depression and suicide attempt as risk factors for incident unprovoked seizures (2006) Annals of Neurology, 59 (1), pp. 35-41. , [PMID, 16217743
- Higgins, J.P., Altman, D.G., Sterne, J.A., Chapter 8: Assessing risk of bias in included studies. In: Higgins JP, Churchill R, Chandler J, Cumpston MS (editors). Cochrane Handbook for Systematic Reviews of Interventions version 5.2.0 (updated June 2017). The Cochrane Collaboration, 2017 Available from www.training.cochrane.org/handbook, , editor(s)
- (2012) Epilepsy Across the Spectrum: Promoting Health and Understanding, , England M, Liverman C, Schultz A, Strawbridge L (eds) edition, Washington, DC, National Academies Press, [ISBN 978-0-309-25506-6] [PMID, 22993876
- Jacoby, A., Baker, G.A., Quality-of-life trajectories in epilepsy: a review of the literature (2008) Epilepsy & Behavior, 12 (4), pp. 557-571. , [PMID, 18158270
- Jehi, L., Responsive neurostimulation: the hope and the challenges (2014) Epilepsy Currents, 14 (5), pp. 270-271. , [PMID, 25346636
- Jones, N.C., O'Brien, T.J., Stress, epilepsy, and psychiatric comorbidity: how can animal models inform the clinic? (2013) Epilepsy & Behavior, 26 (3), pp. 363-369. , [PMID, 23099287
- Kanner, A.M., Depression and epilepsy: a new perspective on two closely related disorders (2006) Epilepsy Currents, 6 (5), pp. 141-146. , [PMID, 17260039
- Kanner, A.M., Byrne, R., Chicharro, A., Wuu, J., Frey, M., A lifetime psychiatric history predicts a worse seizure outcome following temporal lobectomy (2009) Neurology, 72 (9), pp. 793-799. , [PMID, 19255406
- Kwan, P., Brodie, M.J., Early identification of refractory epilepsy (2000) New England Journal of Medicine, 342 (5), pp. 314-319. , [PMID, 10660394
- Larson, A.M., Ryther, R.C., Jennesson, M., Geffrey, A.L., Bruno, P.L., Anagnos, C.J., Impact of pediatric epilepsy on sleep patterns and behaviors in children and parents (2012) Epilepsia, 53 (7), pp. 1162-1169. , [PMID, 22594377
- Dorris, L., Broome, H., Wilson, M., Grant, C., Three-month outcomes of an RCT psychosocial group intervention for young people with epilepsy (PIE) (2016) Epilepsia, 57, p. 14. , x-wiley/crsRef/14417471
- Lefebvre, C., Glanville, J., Briscoe, S., Littlewood, A., Marshall, C., Technical Supplement to Chapter 4: Searching for and selecting studies. In: Higgins JP, Thomas J, Chandler J, Cumpston MS, Li T, Page MJ, et al (eds). Cochrane Handbook for Systematic Reviews of Intervent
- Cook, M., Stephenson, J., The impact of brief lifestyle self-management education for the control of seizures (2019) British Journal of Nursing, 28 (6), pp. 348-354. , Edward K-L,, Giandinoto J-A.,] [] [PMID, x-wiley/crsRef/14417473 dx.doi.org/10.12968/bjon.2019.28.6.348 30925235
- Fraser, R.T., Johnson, E.K., Lashley, S., Barber, J., Chaytor, N., Miller, J., Paces in epilepsy: results of a self-management randomized controlled trial (2015) Epilepsy Currents, 15, p. 200. , x-wiley/crsRef/14417474
- Fraser, R.T., Johnson, E.K., Lashley, S., Barber, J., Chaytor, N., Miller, J., The program for active consumer engagement in self-management (PACES) in epilepsy (2015) Epilepsia, 56, p. 49. , x-wiley/crsRef/6944714
- Fraser, R.T., Johnson, E.K., Lashley, S., Barber, J., Chaytor, N., Miller, J.W., PACES in epilepsy: results of a self-management randomised controlled trial (2015) Epilepsia, 56 (8), pp. 1264-1274. , [PMID, x-wiley/crsRef/6944715 26122460
- Gandy, M., Sharpe, L., Nicholson Perry, K., Thayer, Z., Miller, L., Boserio, J., Cognitive behaviour therapy to improve mood in people with epilepsy: a randomised controlled trial (2014) Cognitive Behaviour Therapy, 43 (2), pp. 153-166. , [PMID, x-wiley/crsRef/6944717 24635701
- Gilliam, F.G., Black, K., Carter, J., Freedland, K.E., Sheline, Y.I., A trial of sertraline or cognitive behavior therapy for depression in epilepsy (2019) Annals of Neurology, 86 (4), pp. 552-560. , Tsai W-Y,] [] [PMID, x-wiley/crsRef/14417476 dx.doi.org/10.1002/ana.25561 31359460
- Helde, G., Bovim, G., Bråthen, G., Brodtkorb, E., A structured, nurse-led intervention program improves quality of life in patients with epilepsy: a randomised, controlled trial (2005) Epilepsy & Behavior, 7 (3), pp. 451-457. , [PMID, x-wiley/crsRef/6944719 16087407
- Hosseini, N., Mokhtari, S., Momeni, E., Vossoughi, M., Barekatian, M., Effect of motivational interviewing on quality of life in patients with epilepsy (2016) Epilepsy & Behavior, 55, pp. 70-74. , [PMID, x-wiley/crsRef/6944721 26773672
- Hum, K.M., Chan, C.J., Gane, J., Conway, L., McAndrews, M.P., Smith, M.L., Do distance-delivery group interventions improve depression in people with epilepsy? (2019) Epilepsy & Behavior, 98 (Pt A), pp. 153-160. , [] [PMID, x-wiley/crsRef/14417478 dx.doi.org/10.1016/j.yebeh.2019.06.037 31374471
- Jantzen, S., Muller-Godeffroy, E., Hallfahrt-Krisl, T., Aksu, F., Pust, B., Kohl, B., FLIP&FLAP-a training programme for children and adolescents with epilepsy, and their parents (2009) Seizure, 18 (7), pp. 478-486. , [] [PMID, x-wiley/crsRef/6944723 19477662
- Leenen, L.A., Wijnen, B.F., Kessels, A.G., Chan, H., de Kinderen, R.J., Evers, S.M., Effectiveness of a multicomponent self-management intervention for adults with epilepsy (ZMILE study): a randomized controlled trial (2018) Epilepsy & Behavior, 80, pp. 259-265. , [] [PMID, x-wiley/crsRef/14417480 dx.doi.org/10.1016/j.yebeh.2018.01.019 29449140
- Wijnen, B., Leenen, L., De Kinderen, R., Van Heugten, C., Majoie, M., Evers, S., An economic evaluation of a multicomponent self-management intervention for adults with epilepsy (ZMILE study) (2017) European Journal of Neurology, 24, p. 72. , x-wiley/crsRef/14417481
- Wijnen, B.F., Leenen, L.A., de Kinderen, R.J., van Heugten, C.M., Majoie, M.H., Evers, S.M., An economic evaluation of a multicomponent self-management intervention for adults with epilepsy (ZMILE study) (2017) Epilepsia, 58 (8), pp. 1398-1408. , [] [PMID, x-wiley/crsRef/14417482 dx.doi.org/10.1111/epi.13806 28589669
- Lua, P.L., Neni, W.S., A randomised controlled trial of an SMS-based mobile epilepsy education system (2013) Journal of Telemedicine and Telecare, 19 (1), pp. 23-28. , [PMID, x-wiley/crsRef/6944725 23390210
- Lua, P.L., Neni, W.S., Health-related quality of life improvement via telemedicine for epilepsy: printed versus SMS-based education intervention (2013) Quality of Life Research, 22 (8), pp. 2123-2132. , [PMID, x-wiley/crsRef/6944726 23329469
- Lundgren, T., Dahl, J., Melin, L., Kies, B., Evaluation of acceptance and commitment therapy for drug refractory epilepsy: a randomised controlled trial in South Africa - a pilot study (2006) Epilepsia, 47 (12), pp. 2173-2179. , [PMID, x-wiley/crsRef/6944728 17201719
- Dahl, J.C., Lundgren, T.L., Yardi, N., Evaluation of short term ACT psychotherapy and yoga in a RCT trial for refractory seizures in India (2005) Epilepsia, 46 Suppl 6, p. 196. , x-wiley/crsRef/6944730
- Lundgren, T., Dahl, J., Yardi, N., Melin, L., Acceptance and Commitment Therapy and yoga for drug-refractory epilepsy: a randomised controlled trial (2008) Epilepsy & Behavior, 13 (1), pp. 102-108. , [PMID, x-wiley/crsRef/6944731 18343200
- Martinović, Z., Simonović, P., Djokić, R., Preventing depression in adolescents with epilepsy (2006) Epilepsy & Behavior, 9 (4), pp. 619-624. , [] [PMID, x-wiley/crsRef/6944733 17049927
- May, T.W., Pfäfflin, M., The efficacy of an educational treatment program for patients with epilepsy (MOSES): results of a controlled, randomised study (2002) Epilepsia, 43 (5), pp. 539-549. , [] [PMID, x-wiley/crsRef/6944735 12027917
- Meyer, B., Weiss, M., Holtkamp, M., Arnold, S., Brückner, K., Schröder, J., Effects of an epilepsy-specific Internet intervention (Emyna) on depression: results of the ENCODE randomized controlled trial (2019) Epilepsia, 60 (4), pp. 656-668. , [] [PMID, x-wiley/crsRef/14417484 30802941
- Meyer, B., Weiss, M., Holtkamp, M., Arnold, S., Bruckner, K., Schroder, J., Protocol for the ENCODE trial: evaluating a novel online depression intervention for persons with epilepsy (2017) BMC Psychiatry, 17, p. 55. , [] [PMID, x-wiley/crsRef/14417485 28173780
- Orjuela-Rojas, J.M., Martinez-Juarez, I.E., Ruiz-Chow, A., Crail-Melendez, D., Treatment of depression in patients with temporal lobe epilepsy: a pilot study of cognitive behavioral therapy vs. selective serotonin reuptake inhibitors (2015) Epilepsy & Behavior, 51, pp. 176-181. , [PMID, x-wiley/crsRef/6944737 26284748
- Pakpour, A.H., Gholami, M., Esmaeili, R., Naghibi, S.A., Updegraff, J.A., Molloy, G.J., A randomised controlled multimodal behavioral intervention trial for improving antiepileptic drug adherence (2015) Epilepsy & Behavior, 52 (Pt A), pp. 133-142. , [PMID, x-wiley/crsRef/6944739 26414343