Detection of coinfection with Chikungunya virus and Dengue virus serotype 2 in serum samples of patients in State of Tocantins, Brazil
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Citações na Scopus
16
Tipo de produção
article
Data de publicação
2020
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCIENCE LONDON
Autores
MARINHO, Robson dos Santos S.
DURO, Rodrigo L. Sanz
SANTOS, Giulia L.
HUNTER, James
TELES, Maria da Aparecida Rodrigues
BRUSTULIN, Rafael
DIAZ, Ricardo S.
V, Shirley Komninakis
Citação
JOURNAL OF INFECTION AND PUBLIC HEALTH, v.13, n.5, p.724-729, 2020
Resumo
Background: The co-circulation of Chikungunya (CHIKV), Dengue (DENV) and Zika (ZIKV) viruses increased the risk of outbreaks and coinfections among them. Here, we report cases of coinfection in clinical samples from state of Tocantins, Brazil. Methods: In 2017, the Central Public Health Laboratory (LACEN) received samples of patients who consulted health units with symptoms compatible with arboviral infections. A total of 102 samples were sent to the Retrovirology Laboratory at the Federal University of Sao Paulo, where they were tested by RT-qPCR to confirm DENV, ZIKV and CHIKV infections and to detect coinfected patients. Results: We identified with CHIKV monoinfection (52), DENV serotypes 1 (28) and serotypes 2 (22). We did not detect ZIKV. Five patients were characterized with coinfection involving CHIKV and DENV serotype 2. Conclusions: The presence of co-circulating arboviruses increases the chance of coinfection and demonstrates the importance of differential diagnosis and vector control. (C) 2020 Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.
Palavras-chave
Arbovirus, RT-qPCR, Coinfection, Chikungunya, Dengue
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