Correlation between novelty-seeking and harm-avoidance with depression and anxiety in Parkinson's disease
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Tipo de produção
conferenceObject
Data de publicação
2012
Título da Revista
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Título do Volume
Editora
WILEY-BLACKWELL
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Citação
MOVEMENT DISORDERS, v.27, suppl.1, p.S269-S270, 2012
Resumo
Background: Lower novelty-seeking (NS) and higher harm-avoidance (HA) are characteristics often found in depressive patients. Depression is a comorbidity often found in PD patients. However, recent studies debate whether depressive-like personality traits in PD patients result from dopaminergic degeneration or are related to depression symptoms present in PD. Methods: 61 advanced PD patients and 42 healthy volunteers (HV) were submitted to personality assessment through Temperament and Character Inventory by Cloninger and to depressive and anxiety symptoms assessment through Hamilton Scales for Anxiety (Ham-A) and Depression (Ham-D). Results: PD group showed NS1 significantly lower 4,96 (SD: 2,05) and higher HA4 4,96 (SD: 1,72) than HV. However, PD group and HV did not differ significantly in Anxiety and Depression scores. Conclusions: The present data suggest that depression is not responsible for depressive-like features in PD. Following this reasoning, we can state that these personality traits can be understood independently and, therefore, as part of the motor treatment of the PD patients, a clinical follow-up of the personality traits is necessary. Further studies should investigate those personality traits in PD patients after DBS.