PET/CT in soft tissue sarcomas

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bookPart
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2022
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ELSEVIER
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ETCHEBEHERE, E.
CASALI, A.
ETCHEBEHERE, M.
Citação
Etchebehere, E.; Munhoz, R. R.; Casali, A.; Etchebehere, M.. PET/CT in soft tissue sarcomas. In: . Nuclear Medicine and Molecular Imaging: Volume 1-4, v.3: ELSEVIER, 2022. p.426-444.
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Soft tissue sarcomas are a diverse group of rare malignant tumors of mesenchymal origin. Clinical diagnosis of soft tissue sarcoma poses a dilemma since the differentiation of a benign from a malignant lesion might be challenging. In addition to the risk of local relapse, these tumors may metastasize, mainly to the lungs, but also to other tissues, and evaluation of the extent of disease and subsequent response to therapy may be difficult. Following local or systemic therapies, tumor fibrosis might occur and can be confounded with viable tumor tissue. FDG PET/CT is a molecular imaging modality that uses the tumor metabolism to evaluate aggressiveness, the extent of disease, treatment response, and differentiation of benign from malignant lesions. This chapter will discuss the potential added value of FDG PET/CT in soft tissue sarcomas. © 2022 Elsevier Inc. All rights reserved.
Palavras-chave
<sup>18</sup>F-FDG, Metastasis, Oncology, PET/CT, Prognosis, Soft tissue sarcoma
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