Chitosan: Applications in Drug Delivery System

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorKUMAR, Suresh
dc.contributor.authorDHIMAN, Ruby
dc.contributor.authorPRUDENCIO, Carlos R.
dc.contributor.authorCOSTA, Antonio Charlys da
dc.contributor.authorVIBHUTI, Arpana
dc.contributor.authorLEAL, Elcio
dc.contributor.authorCHANG, Chung-Ming
dc.contributor.authorRAJ, Vethakkani Samuel
dc.contributor.authorPANDEY, Ramendra Pati
dc.date.accessioned2023-04-14T18:06:32Z
dc.date.available2023-04-14T18:06:32Z
dc.date.issued2023
dc.description.abstractChitin and chitosan have unique structures with significant functional groups carrying useful chemical capabilities. Chitin and chitosan are acknowledged as novel biomaterials with advantageous biocompatibility and biodegradability. Chitosan is a polysaccharide that is made from chitin. There have been several attempts to employ this biopolymer in the biomedical area. This material's application in the production of artificial skin, drug targeting, and other areas is explored. The most prevalent strategies for recovering chitin from sea organisms are described and various pharmacological and biological uses are discussed. This review article targets drug delivery with the help of chitosan derived nanomaterial. The drug delivery system applications through nonmaterial have encountered a considerable role in the pharmaceutical, medical, biological, and other sectors in recent years. Nanomaterials have advanced applications as novel drug delivery systems in many fields, especially in industry, biology, and medicine. In the biomedical and pharmaceutical arena, the natural polymer-based nanoparticulate method has now been widely studied as particulate vehicles. By mixing alginate with other biopolymers, by immobilizing specific molecules such as sugar molecules and peptides by chemical or physical cross-linking, different properties and structures such as biodegradability, gelling properties, mechanical strength, and cell affinity can be obtained. Owing to their inherent ability to deliver both hydrophilic and hydrophobic drug molecules, increase stability, decrease toxicity, and enhance commonly formulated medications, these particles are now widely used in imaging and molecular diagnostics, cosmetics, household chemicals, sunscreens, radiation safety, and novel drug delivery.eng
dc.description.indexMEDLINE
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus
dc.identifier.citationMINI-REVIEWS IN MEDICINAL CHEMISTRY, v.23, n.2, p.187-191, 2023
dc.identifier.doi10.2174/1389557522666220609102010
dc.identifier.eissn1875-5607
dc.identifier.issn1389-5575
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/53123
dc.language.isoeng
dc.publisherBENTHAM SCIENCE PUBL LTDeng
dc.relation.ispartofMini-Reviews in Medicinal Chemistry
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright BENTHAM SCIENCE PUBL LTDeng
dc.subjectBiopolymerseng
dc.subjectphysicochemical propertieseng
dc.subjectbiological propertieseng
dc.subjectnanomaterialseng
dc.subjectnanotoxicityeng
dc.subjectpharmaceutical nanotechnologyeng
dc.subjecttoxicological effecteng
dc.subject.otherchitineng
dc.subject.wosChemistry, Medicinaleng
dc.titleChitosan: Applications in Drug Delivery Systemeng
dc.typearticleeng
dc.type.categoryrevieweng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.affiliation.countryÍndia
hcfmusp.affiliation.countryTaiwan
hcfmusp.affiliation.countryisoin
hcfmusp.affiliation.countryisotw
hcfmusp.author.externalKUMAR, Suresh:Govt India, Minist Hlth & Family Welf, Natl Inst Biol, New Delhi, India
hcfmusp.author.externalDHIMAN, Ruby:SRM Univ, Ctr Drug Design Discovery & Dev C4D, Delhi, Haryana, India
hcfmusp.author.externalPRUDENCIO, Carlos R.:Adolfo Lutz Inst, Ctr Immunol, Sao Paulo, SP, Brazil
hcfmusp.author.externalVIBHUTI, Arpana:SRM Univ, Ctr Drug Design Discovery & Dev C4D, Delhi, Haryana, India
hcfmusp.author.externalLEAL, Elcio:Univ Fed Para, Lab Diversidade Viral, Inst Ciencias Biol, BR-66075000 Belem, PA, Brazil
hcfmusp.author.externalCHANG, Chung-Ming:Chang Gung Univ, Biotechnol Ind, 259, Taoyuan City 33302, Taiwan
hcfmusp.author.externalRAJ, Vethakkani Samuel:SRM Univ, Ctr Drug Design Discovery & Dev C4D, Delhi, Haryana, India
hcfmusp.author.externalPANDEY, Ramendra Pati:SRM Univ, Ctr Drug Design Discovery & Dev C4D, Delhi, Haryana, India; SRM Univ, NCR, Ctr Drug Design Discovery & Dev C4D, Sonepat 131029, Haryana, India
hcfmusp.citation.scopus8
hcfmusp.contributor.author-fmusphcANTONIO CHARLYS DA COSTA
hcfmusp.description.beginpage187
hcfmusp.description.endpage191
hcfmusp.description.issue2
hcfmusp.description.volume23
hcfmusp.origemWOS
hcfmusp.origem.pubmed35692143
hcfmusp.origem.scopus2-s2.0-85143620210
hcfmusp.origem.wosWOS:000950445100006
hcfmusp.publisher.citySHARJAHeng
hcfmusp.publisher.countryU ARAB EMIRATESeng
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relation.isAuthorOfPublication.latestForDiscovery492ae3c9-3cad-4f58-8008-cd444003e119
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