Effect of coffee consumption on blood pressure and exercise tolerance

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2012
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OXFORD UNIV PRESS
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EUROPEAN HEART JOURNAL, v.33, suppl.1, p.301-301, 2012
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Purpose: Coffee is the most abundantly consumed stimulant worldwide. However, its cardiovascular safely remains controversial. Some studies suggest coffee consumption acutely can determine a slight blood pressure raise and improve exercise tolerance. AIM: We evaluated blood pressure and exercise tolerance before and after daily chronic coffee consumption in a group of healthy volunteers and in patients with coronary artery disease. Methods: We did a prospective random crossed-over trial to evaluate two different types of roasted coffee. All individuals were oriented by the same nutritionist and put on 3 weeks washout for caffeine beverages and foods. Then they were randomly assigned to start drinking filtered coffee first in one style-roasted coffee and then crossed-over to the other style. Ground coffee beans, provided for four weeks each, were medium-dark (MD) and dark (D) roasts. After 4 weeks there were cross-over with a total of 8 weeks of drinking coffee. All individuals were taught the amount of coffee to brew each time. They get instructions to drink 450 to 600ml every single day. In the baseline and after each period of drinking they were submitted to treadmill test and ambulatory blood pressure monitoring (24-h ABPM). We did analyze average systolic blood pressure (SBP) and diastolic blood pressure (DBP) from 24-h ABPM, total exercise time(TExercise)and double product (DP) from treadmill test. Variable means were evaluated by the analysis of variance for repeated measures. Results: We evaluated 80 subjects (26 with coronary artery disease and 54 healthy volunteers) with 53.4±13.5 years old, 35 men and 45 women (see table). Conclusions: Both roast raised total exercise time capacity, without an increase in double product. Medium dark roasted coffee consumption, but not dark, promoted a slight blood pressure elevation. These findings suggest that there are substances other than caffeine that raises blood pressure and is degraded by roasting.
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