Lymphedema in Cancer Patients

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2022
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SPRINGER INTERNATIONAL PUBLISHING
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de Andrade, M. F. C.; Bergmann, A.; Montag, E.; Munaretto, J. B.; Jacomo, A.. Lymphedema in Cancer Patients. In: . Vascular Surgery in Oncology: SPRINGER INTERNATIONAL PUBLISHING, 2022. p.501-520.
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Metastasis to distant organs is the most important factor related to cancer survival. Tumor cells spread via blood and lymphatic vessels, systems responsible for transporting fluid and cells. Besides its structural role in cancer metastasis, the lymphatic system displays a critical functional interaction with developing tumors. In clinical settings, full evaluation of the lymphatic system involvement is crucial for treatment and prognosis in cancer patients. Comprehension of physiological and pathological processes involving the lymphatic system is a continuously growing field of basic and clinical research due to recent advances in molecular Lymphology. However, the most interesting biological aspects of lymphatic metastasis of cancer are beyond our objective in this chapter. Here we will focus on the consequences of cancer spread and therapeutic approaches and their impact on the lymphatic system. The knowledge of basic function, structure and distribution of the lymphatic system is essential to diagnosis and treatment in Oncology. In this chapter we will highlight relevant aspects of lymphatic anatomy as well as current topics in conservative and surgical treatment of lymphedema. © Springer Nature Switzerland AG 2022.
Palavras-chave
Anatomy, Cancer, Lymph nodes, Lymphatic system, Lymphedema, Rehabilitation, Surgery
Referências
  1. Bagay L., Lymphedema, Essentials of physical medicine and rehabilitation, pp. 735-739, (2020)
  2. Shaitelman S.F., Cromwell K.D., Rasmussen J.C., Stout N.L., Armer J.M., Lasinski B.B., Cormier J.N., Recent progress in the treatment and prevention of cancer-related lymphedema, CA Canc J Clin, 65, 1, pp. 55-81, (2015)
  3. Andrade M.F.C., Buchpiegel C.A., De Luccia N., Lymph absorption and transport in acute deep venous thrombosis of the lower limbs, Lymphology, 33, pp. 95-98, (2000)
  4. Levick J.R., Michel C.C., Microvascular fluid exchange and the revised Starling principle, Cardiovasc Res, 87, 2, pp. 198-210, (2010)
  5. Jacomo A.L., Rodrigues A.J., Anatomia clínica do sistema linfático, Linfologia básica, pp. 19-34, (1995)
  6. Kubik S., Anatomy of the lymphatic system, Textbook of lymphology, pp. 1-167, (2003)
  7. Rouviere H., Anatomie descriptive et topographique des lymphatiques de l’homme, Anatomie des lymphatiques de l’homme, pp. 1-8, (1981)
  8. Andrade M., Jacomo A., Anatomy of the human lymphatic system, Cancer metastasis and the lymphovascular system, pp. 55-74, (2007)
  9. Caplan I., Ciucci J.L., Drenaje linfático superficial del miembro superior, Linfologia, 1, pp. 33-36, (1995)
  10. Cuadrado G.A., Andrade M.F.C., Akamatsu F.E., Jacomo A.L., Anatomy of the lymphatic drainage of the upper limb and breast and its role in lymphedema prevention after breast cancer treatment, Int J Morphol, 34, 3, pp. 1117-1122, (2016)
  11. Jacomo A.L., Rodrigues A.J., Figueira L.N.T., Drenagem linfática superficial da pele da região plantar, Acta Ortop Bras, 2, pp. 35-37, (1994)
  12. Andrade M.F.C., Jacomo A.L., Sistema linfático dos membros inferiores, Anatomia cirúrgica, pp. 726-728, (1999)
  13. Rockson S.G., Lymphedema after breast cancer treatment, N Engl J Med, 379, pp. 1937-1944, (2018)
  14. Dessources K., Aviki E., Leitao M.M., Lower extremity lymphedema in patients with gynecologic malignancies, Int J Gynecol Cancer, 30, 2, pp. 252-260, (2020)
  15. Vignes S., Lymphedema: From diagnosis to treatment, Rev Med Interne, 38, 2, pp. 97-105, (2017)
  16. Committee E., The diagnosis and treatment of peripheral lymphedema: 2016 consensus document of the International Society of Lymphology, Lymphology, 49, 4, pp. 170-184, (2016)
  17. Noh S., Hwang J.H., Yoon T.H., Chang H.J., Chu I.H., Kim J.H., Limb differences in the therapeutic effects of complex decongestive therapy on edema, quality of life, and satisfaction in lymphedema patients, Ann Rehabil Med, 39, 3, pp. 347-359, (2015)
  18. Lasinski B.B., McKillip Thrift K., Squire D., Austin M.K., Smith K.M., Wanchai A., Green J.M., Stewart B.R., Cormier J.N., Armer J.M., A systematic review of the evidence for complete decongestive therapy in the treatment of lymphedema from 2004 to 2011, PMR, 4, 8, pp. 580-601, (2012)
  19. Jeffs E., Ream E., Taylor C., Bick D., Clinical effectiveness of decongestive treatments on excess arm volume and patient-centered outcomes in women with early breast cancer-related arm lymphedema: A systematic review, JBI Database System Rev Implement Rep, 16, 2, pp. 453-506, (2018)
  20. Mobarakeh Z.S., Mokhtari-Hesari P., Lotfi-Tokaldany M., Montazeri A., Heidari M., Zekri F., Combined decongestive therapy and reduction of pain and heaviness in patients with breast cancer-related lymphedema, Support Care Cancer, 27, 10, pp. 3805-3811, (2019)
  21. Vignes S., Porcher R., Champagne A., Dupuy A., Predictive factors of response to intensive decongestive physiotherapy in upper limb lymphedema after breast cancer treatment: A cohort study, Breast Cancer Res Treat, 98, 1, pp. 1-6, (2006)
  22. Eyigor S., Cinar E., Caramat I., Unlu B.K., Factors influencing response to lymphedema treatment in patients with breast cancer-related lymphedema, Support Care Cancer, 23, 9, pp. 2705-2710, (2015)
  23. Duyur Cakit B., Pervane Vural S., Ayhan F.F., Complex decongestive therapy in breast cancer-related lymphedema: Does obesity affect the outcome negatively?, Lymphat Res Biol, 17, 1, pp. 45-50, (2019)
  24. Williams A., Manual lymphatic drainage: Exploring the history and evidence base, Br J Community Nurs, 15, pp. S18-S24, (2010)
  25. Tabatabaee A., Tafreshi M.Z., Rassouli M., Aledavood S.A., Alavimajd H., Farahmand S.K., Effect of therapeutic touch in patients with cancer: A literature review, Med Arch, 70, 2, pp. 142-147, (2016)
  26. Bergmann A., Ferreira M.G.C.L., Aguiar S.S., Dias R.A., Abrahao K.S., Paltrinieri E., Allende R.M., Andrade M.F.C., Physiotherapy in upper limb lymphedema after breast cancer treatment: A randomized study, Lymphology, 47, pp. 82-91, (2014)
  27. Tambour M., Holt M., Speyer A., Christensen R., Gram B., Manual lymphatic drainage adds no further volume reduction to Complete Decongestive Therapy on breast cancer-related lymphoedema:A multicentre, randomised, single-blind trial, Br J Cancer, 119, 10, pp. 1215-1222, (2018)
  28. Gradalski T., Ochalek K., Kurpiewska J., Complex decongestive lymphatic therapy with or without Vodder II manual lymph drainage in more severe chronic postmastectomy upper limb lymphedema: A randomized noninferiority prospective study, J Pain Sym Man, 50, 6, pp. 750-757, (2015)
  29. Bjork R., Ehmann S.S.T.R.I.D.E., Professional guide to compression garment selection for the lower extremity, J Wound Care, 28, Sup6a, pp. 1-44, (2019)
  30. Bergmann A., Fabro E.A.N., Costa R.M., Enfaixamento compressivo no tratamento do linfedema de extremidades, Raciocínio clinico em bandagens terapêuticas, pp. 463-479, (2018)
  31. Williams A., A review of the evidence for adjustable compression wrap devices, J Wound Care, 25, 5, pp. 242-247, (2016)
  32. Lee N., Lawrance S., Haddenham Easywrap: An alternative to compression bandaging in chronic oedema and wound care, Br J Community Nurs, 24, Sup4, pp. S22-S28, (2019)
  33. Pujol-Blaya V., Salinas-Huertas S., Catasus M.L., Pascual T., Belmonte R., Effectiveness of a precast adjustable compression system compared to multilayered compression bandages in the treatment of breast cancer-related lymphoedema: A randomized, single-blind clinical trial, Clin Rehabil, 33, 4, pp. 631-641, (2019)
  34. Partsch H., Reliable self-application of short stretch leg compression: Pressure measurements under self-applied, adjustable compression wraps, Phlebology, 34, 3, pp. 208-213, (2019)
  35. Todd M., Stubbs C., Pugh S., Mobiderm Autofit: An adjustable sleeve that enables patients to self-manage lymphoedema, Br J Community Nurs, 23, Sup4, pp. S22-S28, (2018)
  36. Campanholi L.L., Lopes G.L., Mansani F.P., Bergmann A., Baiocchi J.M.T., The validity of an adjustable compression Velcro wrap for the treatment of patients with upper limb lymphedema secondary to breast cancer: A pilot study, Mastology, 27, 3, pp. 206-212, (2017)
  37. Panchik D., Masco S., Zinnikas P., Hillriegel B., Lauder T., Suttmann E., Chinchilli V., Mc Beth M., Hermann W., Effect of exercise on breast cancer-related lymphedema: What the lymphatic surgeon needs to know, J Reconstr Microsurg, 35, 1, pp. 37-45, (2019)
  38. Rooney L., Cooper-Stanton G., Cave-Senior J., Compression therapy and exercise: Enhancing outcomes, Br J Community Nurs, 23, 7, pp. 343-346, (2018)
  39. Luz R.P.C., Simao Haddad C.A., Rizzi S.K.L.A., Elias S., Nazario A.C.P., Facina G., Complex therapy physical alone or associated with strengthening exercises in patients with lymphedema after breast cancer treatment: A controlled clinical trial, Asian Pac J Cancer Prev, 19, 5, pp. 1405-1410, (2018)
  40. Baumann F.T., Reike A., Reimer V., Schumann M., Hallek M., Taaffe D.R., Newton R.U., Galvao D.A., Effects of physical exercise on breast cancer-related secondary lymphedema: A systematic review, Breast Cancer Res Treat, 170, 1, pp. 1-13, (2018)
  41. Kizil R., Dilek B., Sahin E., Engin O., Soylu A.C., Akalin E., Alper S., Is continuous passive motion effective in patients with lymphedema? A randomized controlled trial, Lymphat Res Biol, 16, 3, pp. 263-269, (2018)
  42. Jones A., Woods M., Malhotra K., Critical examination of skin care self-management in lymphoedema, Br J Community Nurs, 24, Sup10, pp. S6-S10, (2019)
  43. Fife C.E., Farrow W., Hebert A.A., Armer N.C., Stewart B.R., Cormier J.N., Armer J.M., Skin and wound care in lymphedema patients: A taxonomy, primer, and literature review, Adv Skin Wound Care, 30, 7, pp. 305-318, (2017)
  44. Douglass J., Mableson H.E., Martindale S., Kelly-Hope L.A., An enhanced self-care protocol for people affected by moderate to severe lymphedema, Methods Protoc, 2, 3, (2019)
  45. Tantawy S.A., Abdelbasset W.K., Nambi G., Kamel D.M., Comparative study between the effects of kinesio taping and pressure garment on secondary upper extremity lymphedema and quality of life following mastectomy: A randomized controlled trial, Integr Cancer Ther, 18, pp. 1-10, (2019)
  46. Kasawara K.T., Mapa J.M.R., Ferreira V., Added M.A.N., Shiwa S.R., Carvas N., Batista P.A., Effects of kinesio taping on breast cancer-related lymphedema: A meta-analysis in clinical trials, Physiother Theory Pract, 34, 5, pp. 337-345, (2018)
  47. Gatt M., Willis S., Leuschner S., A meta-analysis of the effectiveness and safety of kinesiology taping in the management of cancer-related lymphedema, Eur J Cancer Care, 26, 5, (2016)
  48. Martins J.C.M., Aguiar S.S., Fabro E.A.N., Costa R.M., Lemos T.V., Sa V.G.G., Et al., Safety and tolerability of Kinesio® Taping in patients with arm lymphedema: Medical device clinical study, Support Care Cancer, 24, 3, pp. 1119-1124, (2016)
  49. Morris R.J., Intermittent pneumatic compression systems and applications, J Med Eng Technol, 32, pp. 179-188, (2008)
  50. Feldman J.L., Stout N.L., Wanchai A., Stewart B.R., Cormier J.N., Armer J.M., Intermittent pneumatic compression therapy: A systematic review, Lymphology, 45, 1, pp. 13-25, (2012)
  51. Zaleska M., Olszewski W.L., Jain P., Gogia S., Rekha A., Mishra S., Durlik M., Pressures and timing of intermittent pneumatic compression devices for efficient tissue fluid and lymph flow in limbs with lymphedema, Lymphat Res Biol, 11, 4, pp. 227-232, (2013)
  52. Phillips J.J., Gordon S.J., Intermittent pneumatic compression dosage for adults and children with lymphedema: A systematic review, Lymphat Res Biol, 17, 1, pp. 2-18, (2019)
  53. Shao Y., Qi K., Zhou Q.H., Zhong D.S., Intermittent pneumatic compression pump for breast cancer-related lymphedema: A systematic review and meta-analysis of randomized controlled trials, Oncol Res Treat, 37, 4, pp. 170-174, (2014)
  54. Ridner S.H., Poage-Hooper E., Kanar C., Doersam J.K., Bond S.M., Dietrich M.S., A pilot randomized trial evaluating low-level laser therapy as an alternative treatment to manual lymphatic drainage for breast cancer-related lymphedema, Oncol Nurs Forum, 40, 4, pp. 383-393, (2013)
  55. Johansson K., Lie E., Ekdahl C., Lindfeldt J., A randomizedstudy comparing manual lymph drainage with sequential pneumatic compression for treatment of postoperative arm lymphedema, Lymphology, 31, 2, pp. 56-64, (1998)
  56. Rogan S., Taeymans J., Luginbuehl H., Aebi M., Mahnig S., Gebruers N., Therapy modalities to reduce lymphoedema in female breast cancer patients: A systematic review and meta-analysis, Breast Cancer Res Treat, 159, 1, pp. 1-14, (2016)
  57. Sistrunk W.E., Contribution to plastic surgery: Removal of scars by stages
  58. an open operation for extensive laceration of the anal sphincter
  59. the Kondoleon operation for elephantiasis, Ann Surg, 85, pp. 185-193, (1927)
  60. Charles R.H., Elephantiasis Scroti, (1912)
  61. Homans J., The treatment of elephantiasis of the legs: A preliminary report, N Engl J Med, 215, pp. 1099-1104, (1936)
  62. Suami H., Chang D.W., Overview of surgical treatments for breast cancer-related lymphedema, Plast Reconstr Surg, 126, pp. 1853-1863, (2010)
  63. Chang D.W., Lymphaticovenular bypass for lymphedema management in breast cancer patients:A prospective study, Plast Reconstr Surg, 126, pp. 752-758, (2010)
  64. O'Brien B.M., Sykes P., Threlfall G.N., Browning F.S., Microlymphaticovenous anastomoses for obstructive lymph-edema, Plast Reconstr Surg, 60, pp. 197-211, (1977)
  65. Campisi C., Boccardo F., Lymphedema and microsurgery, Microsurgery, 22, pp. 74-80, (2002)
  66. Koshima I., Kawada S., Moriguchi T., Kajiwara Y., Ultrastructural observations of lymphatic vessels in lymphedema in human extremities, Plast Reconstr Surg, 97, pp. 397-405, (1996)
  67. Koshima I., Nanba Y., Tsutsui T., Takahashi Y., Itoh S., Fujitsu M., Minimal invasive lymphaticovenular anastomosis under local anesthesia for leg lymphedema: Is it effective for stage III and IV?, Ann Plast Surg, 53, pp. 261-266, (2004)
  68. Koshima I., Narushima M., Yamamoto Y., Mihara M., Iida T., Recent advancement on surgical treatments for lymphedema, Ann Vasc Dis, 5, pp. 409-415, (2012)
  69. Nagase T., Gonda K., Inoue K., Et al., Treatment of lymph-edema with lymphaticovenular anastomoses, Int J Clin Oncol, 10, pp. 304-310, (2005)
  70. Lahteenvuo M., Honkonen K., Tervala T., Et al., Growth fac-tor therapy and autologous lymph node transfer in lymphedema, Circulation, 123, pp. 613-620, (2011)
  71. Honkonen K.M., Visuri M.T., Tervala T.V., Et al., Lymph nodetransfer and perinodal lymphatic growth factor treatmentfor lymphedema, Ann Surg, 257, pp. 961-967, (2013)
  72. Saaristo A.M., Niemi T.S., Viitanen T.P., Tervala T.V., Hartiala P., Suominen E.A., Microvascular breast reconstruction and lymph node transfer for postmastectomy lymphedema patients, Ann Surg, 255, pp. 468-473, (2012)
  73. Lin C.H., Ali R., Chen S.C., Et al., Vascularized groin lymph node transfer using the wrist as a recipient site for management of postmastectomy upper extremity lymphedema, Plast Reconstr Surg, 123, pp. 1265-1275, (2009)
  74. Cheng M.H., Huang J.J., Nguyen D.H., Et al., A novel approach to the treatment of lower extremity lymphedema by transfer-ring a vascularized submental lymph node flap to the ankle, Gynecol Oncol, 126, pp. 93-98, (2012)
  75. Cheng M.H., Chen S.C., Henry S.L., Tan B.K., Lin M.C., Huang J.J., Vascularized groin lymph node flap transfer for postmastectomy upper limb lymphedema: Flap anatomy, recipient sites, and outcomes, Plast Reconstr Surg, 131, pp. 1286-1298, (2013)
  76. Viitanen T.P., Maki M.T., Seppanen M.P., Suominen E.A., Saaristo A.M., Donor-site lymphatic function after microvascular lymph node transfer, Plast Reconstr Surg, 130, pp. 1246-1253, (2012)
  77. Pons G., Masia J., Loschi P., Nardulli M.L., Duch J., A case of donor-site lymphoedema after lymph node-superficial circumflex iliac artery perforator flap transfer, J Plast Reconstr Aesthet Surg, 67, pp. 119-123, (2014)
  78. Dayan J.H., Dayan E., Smith M.L., Reverse Lymphatic Mapping: A new technique for maximising safety in vascularized lymph node transfer, Plast Reconstr Surg, 135, 1, pp. 277-285, (2015)
  79. Becker C., Hidden G., Transfer of free lymphatic flaps: Microsurgery and anatomical study (in French), J Mal Vasc, 13, pp. 119-122, (1988)
  80. Becker C., Assouad J., Riquet M., Hidden G., Postmastectomy lymphedema: Long-term results following microsurgical lymph node transplantation, Ann Surg, 243, pp. 313-315, (2006)
  81. Montag E., Okada A.Y., Arruda E.G.P., Fonseca A.S., Bromley M., Munhoz A.M., Et al., Influence of vascularized lymph node transfer (VLNT) flap positioning the response to breast cancer-related lymphedema treatment, Rev Col Bras Cir, 46, 2, (2019)
  82. Boccardo F., Casabona F., De Cian F., Friedman D., Murelli F., Puglisi M., Et al., Lymphatic Microsurgical Preventing Healing Approach (LYMPHA) for primary surgical prevention of breast cancer-related lymphedema: Over 4 years follow-up, Microsurgery, 34, 6, pp. 421-424, (2014)
  83. Lawenda B.D., Mondry T.E., Johnstone P.A., Lymphedema: A primer on the identification and management of a chronic condition in oncologic treatment, CA Cancer J Clin, 59, pp. 8-24, (2009)
  84. Szuba A., Shin W.S., Strauss H.W., Rockson S., The third circulation: Radionuclide lymphoscintigraphy in the evaluation of lymphedema, J Nucl Med, 44, pp. 43-57, (2003)
  85. The diagnosis and treatment of peripheral lymphedema:2013 Consensus Document of the International Society of Lymphology, Lymphology, 46, 1, pp. 1-11, (2013)
  86. Williams S.K., Rabbani F., Complications of lymphadenectomy in urologic surgery, Urol Clin North Am, 38, pp. 507-518, (2011)
  87. Abu-Rustum N.R., Alektiar K., Iasonos A., Et al., The incidence of symptomatic lower-extremity lymphedema following treatment of uterine corpus malignancies: A 12-year experience at Memorial Sloan-Kettering Cancer Center, Gynecol Oncol, 103, pp. 714-718, (2006)
  88. Rockson S.G., Rivera K.K., Estimating the population burden of lymphedema, Ann N Y Acad Sci, 1131, pp. 147-154, (2008)
  89. Cormier J.N., Askew R.L., Mungovan K.S., Et al., Lymphedema beyond breast cancer: A systematic review and meta-analysis of cancer-related secondary lymphedema, Cancer, 116, pp. 5138-5149, (2010)
  90. Lyman G.H., Temin S., Edge S.B., Et al., Sentinel lymph node biopsy for patients with early-stage breast cancer: American Society of Clinical Oncology clinical practice guideline update, J Clin Oncol, 32, pp. 1365-1383, (2014)
  91. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines), Breast Cancer, (2020)
  92. Lyman G.H., Giuliano A.E., Somerfield M.R., Et al., American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer, J Clin Oncol, 23, pp. 7703-7720, (2005)
  93. Kaufmann M., Morrow M., von Minckwitz G., Et al., Locoregional treatment of primary breast cancer: Consensus recommendations from an International Expert Panel, Cancer, 116, pp. 1184-1191, (2010)