<p>Nonoperative Management of Rectal Cancer The Watch and Wait Strategy</p>

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorVAILATI, Bruna Borba
dc.contributor.authorJULIAO, Guilherme Pagin Sao
dc.contributor.authorHABR-GAMA, Angelita
dc.contributor.authorPEREZ, Rodrigo Oliva
dc.date.accessioned2022-06-20T15:27:10Z
dc.date.available2022-06-20T15:27:10Z
dc.date.issued2022
dc.description.abstractOver the past few decades, rectal cancer management has become increasingly challenging for multiple reasons. Proper imaging using dedicated magnetic resonance (MR), standardization of total mesorectal excision (TME), and incorporation of neoadjuvant treatment regimens have contributed to a significant decrease in local recurrence rates while minimizing the need for definitive stomas (therefore allowing for sphincter-preservation alternatives).1 & ndash;3 However, the observation of complete tumor response to radiation (RT) or chemoradiation (CRT) led to the proposal of organpreservation strategies with avoidance of immediate surgery and close surveillance (Watch and Wait strategy) in selected patients.4 Initially considered for a very restricted subgroup of patients, the use of more contemporary neoadjuvant treatment regimens has resulted in a higher proportion of patients achieving complete tumor regression.5 The purpose of the present article is to review the current evidence related to the selection criteria and outcomes in patients enrolled in this Watch and Wait strategy. <comment>Superscript/Subscript Available</commenteng
dc.description.indexMEDLINEeng
dc.identifier.citationSURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, v.31, n.2, Special Issue, p.171-182, 2022
dc.identifier.doi10.1016/j.soc.2021.11.003
dc.identifier.eissn1558-5042
dc.identifier.issn1055-3207
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/47115
dc.language.isoeng
dc.publisherW B SAUNDERS CO-ELSEVIER INCeng
dc.relation.ispartofSurgical Oncology Clinics of North America
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright W B SAUNDERS CO-ELSEVIER INCeng
dc.subjectWatch & waiteng
dc.subjectOrgan preservationeng
dc.subjectRectal cancereng
dc.subjectNeoadjuvant therapyeng
dc.subjectClinical complete responseeng
dc.subject.othertransanal endoscopic microsurgeryeng
dc.subject.otherdiffusion-weighted mrieng
dc.subject.otherneoadjuvant chemoradiation therapyeng
dc.subject.otherclinical complete responderseng
dc.subject.otherterm-follow-upeng
dc.subject.otherpostoperative chemoradiotherapyeng
dc.subject.otherinternational watcheng
dc.subject.otherorgan preservationeng
dc.subject.othersequential pet/cteng
dc.subject.othersalvage surgeryeng
dc.subject.wosPhysiologyeng
dc.subject.wosSport Scienceseng
dc.title<p>Nonoperative Management of Rectal Cancer The Watch and Wait Strategy</p>eng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalVAILATI, Bruna Borba:Angelita & Joaquim Gama Inst, Sao Paulo, SP, Brazil; Hosp Alemao Oswaldo Cruz, Sao Paulo, Brazil; Hosp Beneficencia Portuguesa, Sao Paulo, Brazil; Praca Amadeu Amaral 47-111, BR-01327010 Sao Paulo, SP, Brazil
hcfmusp.author.externalJULIAO, Guilherme Pagin Sao:Angelita & Joaquim Gama Inst, Sao Paulo, SP, Brazil; Hosp Alemao Oswaldo Cruz, Sao Paulo, Brazil; Hosp Beneficencia Portuguesa, Sao Paulo, Brazil; Praca Amadeu Amaral 47-111, BR-01327010 Sao Paulo, SP, Brazil
hcfmusp.author.externalPEREZ, Rodrigo Oliva:Angelita & Joaquim Gama Inst, Sao Paulo, SP, Brazil; Hosp Alemao Oswaldo Cruz, Sao Paulo, Brazil; Hosp Beneficencia Portuguesa, Sao Paulo, Brazil
hcfmusp.citation.scopus8
hcfmusp.contributor.author-fmusphcANGELITA HABR GAMA
hcfmusp.description.beginpage171
hcfmusp.description.endpage182
hcfmusp.description.issue2
hcfmusp.description.issueSpecial Issue
hcfmusp.description.volume31
hcfmusp.origemWOS
hcfmusp.origem.pubmed35351272
hcfmusp.origem.scopus2-s2.0-85126041588
hcfmusp.origem.wosWOS:000792764200006
hcfmusp.publisher.cityPHILADELPHIAeng
hcfmusp.publisher.countryUSAeng
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