Guidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathies

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSOUZA, Fernando Henrique Carlos de
dc.contributor.authorARAUJO, Daniel Brito de
dc.contributor.authorVILELA, Veronica Silva
dc.contributor.authorBEZERRA, Mailze Campos
dc.contributor.authorSIMOES, Ricardo Santos
dc.contributor.authorBERNARDO, Wanderley Marques
dc.contributor.authorMIOSSI, Renata
dc.contributor.authorCUNHA, Bernardo Matos da
dc.contributor.authorSHINJO, Samuel Katsuyuki
dc.date.accessioned2019-02-21T17:21:11Z
dc.date.available2019-02-21T17:21:11Z
dc.date.issued2019
dc.description.abstractBackground: Recommendations of the Myopathy Committee of the Brazilian Society of Rheumatology for the management and therapy of systemic autoimmune myopathies (SAM). Main body: The review of the literature was done in the search for the Medline (PubMed), Embase and Cochrane databases including studies published until June 2018. The Prisma was used for the systematic review and the articles were evaluated according to the levels of Oxford evidence. Ten recommendations were developed addressing the management and therapy of systemic autoimmune myopathies. Conclusions: Robust data to guide the therapeutic process are scarce. Although not proven effective in controlled clinical trials, glucocorticoid represents first-line drugs in the treatment of SAM. Intravenous immunoglobulin is considered in induction for refractory cases of SAM or when immunosuppressive drugs are contra-indicated. Consideration should be given to the early introduction of immunosuppressive drugs. There is no specific period determined for the suspension of glucocorticoid and immunosuppressive drugs when individually evaluating patients with SAM. A key component for treatment in an early rehabilitation program is the inclusion of strength-building and aerobic exercises, in addition to a rigorous evaluation of these activities for remission of disease and the education of the patient and his/her caregivers.eng
dc.description.indexMEDLINEeng
dc.description.sponsorshipBrazilian Society of Rheumatology
dc.identifier.citationADVANCES IN RHEUMATOLOGY, v.59, article ID 6, 12p, 2019
dc.identifier.doi10.1186/s42358-019-0048-x
dc.identifier.issn2523-3106
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/30800
dc.language.isoeng
dc.publisherBMCeng
dc.relation.ispartofAdvances in Rheumatology
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright BMCeng
dc.subjectDermatomyositiseng
dc.subjectGuidelineseng
dc.subjectPolymyositiseng
dc.subjectSystemic autoimmune myopathieseng
dc.subjectTreatmenteng
dc.subject.otherpneumocystis-carinii-pneumoniaeng
dc.subject.otherinterstitial lung-diseaseeng
dc.subject.otheridiopathic inflammatory myopathieseng
dc.subject.othercell activating factoreng
dc.subject.otherterm-follow-upeng
dc.subject.otherrefractory polymyositiseng
dc.subject.otherjuvenile dermatomyositiseng
dc.subject.othermycophenolate-mofetileng
dc.subject.othermyositis patientseng
dc.subject.othercyclosporine-aeng
dc.subject.wosRheumatologyeng
dc.titleGuidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathieseng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalARAUJO, Daniel Brito de:UFP, Pelotas, RS, Brazil
hcfmusp.author.externalVILELA, Veronica Silva:Univ Estado Rio De Janeiro, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalBEZERRA, Mailze Campos:HGF, Fortaleza, Ceara, Brazil
hcfmusp.author.externalCUNHA, Bernardo Matos da:Rede Sarah Hosp Reabilitacao, Brasilia, DF, Brazil
hcfmusp.citation.scopus16
hcfmusp.contributor.author-fmusphcFERNANDO HENRIQUE CARLOS DE SOUZA
hcfmusp.contributor.author-fmusphcRICARDO DOS SANTOS SIMOES
hcfmusp.contributor.author-fmusphcWANDERLEY MARQUES BERNARDO
hcfmusp.contributor.author-fmusphcRENATA MIOSSI
hcfmusp.contributor.author-fmusphcSAMUEL KATSUYUKI SHINJO
hcfmusp.description.articlenumber6
hcfmusp.description.volume59
hcfmusp.origemWOS
hcfmusp.origem.pubmed30670084
hcfmusp.origem.scieloSCIELO:S2523-31062019000100301
hcfmusp.origem.scopus2-s2.0-85060375842
hcfmusp.origem.wosWOS:000457521000003
hcfmusp.publisher.cityLONDONeng
hcfmusp.publisher.countryENGLANDeng
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