Percentiles of predicted 10-year cardiovascular disease risk by sex and age in Brazil and their association with estimated risk of long-term atherosclerotic events
dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
dc.contributor.author | CESENA, Fernando Yue | |
dc.contributor.author | GENEROSO, Giuliano | |
dc.contributor.author | SANTOS, Itamar de S. | |
dc.contributor.author | DUNCAN, Bruce B. | |
dc.contributor.author | RIBEIRO, Antonio Luiz P. | |
dc.contributor.author | BRANT, Luisa Caldeira | |
dc.contributor.author | MILL, Jose Geraldo | |
dc.contributor.author | PEREIRA, Alexandre C. | |
dc.contributor.author | BITTENCOURT, Marcio Sommer | |
dc.contributor.author | SANTOS, Raul D. | |
dc.contributor.author | LOTUFO, Paulo A. | |
dc.contributor.author | BENSENOR, Isabela M. | |
dc.date.accessioned | 2024-02-15T14:39:04Z | |
dc.date.available | 2024-02-15T14:39:04Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Objective: Expressing the cardiovascular disease (CVD) risk in relation to peers may complement the estimation of absolute CVD risk. We aimed to determine 10-year CVD risk percentiles by sex and age in the Brazilian population and evaluate their association with estimated long-term atherosclerotic CVD (ASCVD) risk.Methods: A cross-sectional analysis of baseline data from the ELSA-Brasil study was conducted in individuals aged 40-74 years without prior ASCVD. Ten-year CVD risk and long-term ASCVD risk were estimated by the WHO risk score and the Multinational Cardiovascular Risk Consortium tool, respectively. Ten-year risk percentiles were determined by ranking the calculated risks within each sex and age group.Results: Ten-year CVD risk versus percentile plots were constructed for each sex and age group using data from 13,364 participants (55% females; median age, 52 [IQR, 46-59] years). Long-term ASCVD risk was calculated in 12,973 (97.1%) participants. Compared to individuals at the <25th risk percentile, those at the >= 75th percentile had a greater risk of being in the highest quartile of long-term risk (ORs [95% CIs] 6.57 [5.18-8.30] in females and 11.59 [8.42-15.96] in males) in regression models adjusted for age, race, education, and 10-year CVD risk. In both sexes, the association between risk percentile and long-term risk weakened after age 50. A tool for calculating 10-year CVD risk and the corresponding percentile is available at https://bit.ly/3CzPUi6.Conclusions: We established percentiles of predicted 10-year CVD risk by sex and age in the Brazilian population, which independently reflect the estimated long-term ASCVD risk in younger individuals. | eng |
dc.description.index | MEDLINE | |
dc.description.index | PubMed | |
dc.description.index | WoS | |
dc.description.index | Scopus | |
dc.identifier.citation | PREVENTIVE MEDICINE, v.177, article ID 107755, 9p, 2023 | |
dc.identifier.doi | 10.1016/j.ypmed.2023.107755 | |
dc.identifier.eissn | 1096-0260 | |
dc.identifier.issn | 0091-7435 | |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/57818 | |
dc.language.iso | eng | |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | eng |
dc.relation.ispartof | Preventive Medicine | |
dc.rights | restrictedAccess | eng |
dc.rights.holder | Copyright ACADEMIC PRESS INC ELSEVIER SCIENCE | eng |
dc.subject | Heart disease risk factors | eng |
dc.subject | Risk assessment | eng |
dc.subject | Cardiovascular diseases | eng |
dc.subject | ASCVD | eng |
dc.subject | Awareness | eng |
dc.subject | World Health Organization | eng |
dc.subject.other | coronary-artery calcium | eng |
dc.subject.other | health | eng |
dc.subject.other | race | eng |
dc.subject.other | cholesterol | eng |
dc.subject.other | prevention | eng |
dc.subject.other | prevalence | eng |
dc.subject.other | statement | eng |
dc.subject.other | update | eng |
dc.subject.other | gender | eng |
dc.subject.wos | Public, Environmental & Occupational Health | eng |
dc.subject.wos | Medicine, General & Internal | eng |
dc.title | Percentiles of predicted 10-year cardiovascular disease risk by sex and age in Brazil and their association with estimated risk of long-term atherosclerotic events | eng |
dc.type | article | eng |
dc.type.category | original article | eng |
dc.type.version | publishedVersion | eng |
dspace.entity.type | Publication | |
hcfmusp.affiliation.country | Estados Unidos | |
hcfmusp.affiliation.countryiso | us | |
hcfmusp.author.external | CESENA, Fernando Yue:Cenocor, Guarulhos, SP, Brazil; Rua Dr Ramos de Azevedo,159,sala 1510, BR-07012020 Guarulhos, SP, Brazil | |
hcfmusp.author.external | DUNCAN, Bruce B.:Univ Fed Rio Grande do Sul, Sch Med, Porto Alegre, RS, Brazil; Fed Univ Rio Grande, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil | |
hcfmusp.author.external | RIBEIRO, Antonio Luiz P.:Univ Fed Minas Gerais, Fac Med, Dept Internal Med, Belo Horizonte, MG, Brazil; Univ Fed Minas Gerais, Hosp Clin, Telehlth Ctr, Belo Horizonte, MG, Brazil | |
hcfmusp.author.external | BRANT, Luisa Caldeira:Univ Fed Minas Gerais, Fac Med, Dept Internal Med, Belo Horizonte, MG, Brazil | |
hcfmusp.author.external | MILL, Jose Geraldo:Univ Fed Espirito Santo, Dept Physiol Sci, Vitoria, ES, Brazil | |
hcfmusp.author.external | BITTENCOURT, Marcio Sommer:Univ Pittsburgh, Med Ctr, Heart & Vasc Inst, Pittsburgh, PA USA | |
hcfmusp.citation.scopus | 0 | |
hcfmusp.contributor.author-fmusphc | GIULIANO GENEROSO | |
hcfmusp.contributor.author-fmusphc | ITAMAR DE SOUZA SANTOS | |
hcfmusp.contributor.author-fmusphc | ALEXANDRE DA COSTA PEREIRA | |
hcfmusp.contributor.author-fmusphc | RAUL DIAS DOS SANTOS FILHO | |
hcfmusp.contributor.author-fmusphc | PAULO ANDRADE LOTUFO | |
hcfmusp.contributor.author-fmusphc | ISABELA JUDITH MARTINS BENSEñOR | |
hcfmusp.description.articlenumber | 107755 | |
hcfmusp.description.volume | 177 | |
hcfmusp.origem | WOS | |
hcfmusp.origem.pubmed | 37931661 | |
hcfmusp.origem.scopus | 2-s2.0-85176285213 | |
hcfmusp.origem.wos | WOS:001112568400001 | |
hcfmusp.publisher.city | SAN DIEGO | eng |
hcfmusp.publisher.country | USA | eng |
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