Oral lichen planus: case series and experience in a tertiary dermatology service in Brazil

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art_ERTHAL_Oral_lichen_planus_case_series_and_experience_in_2023.PDF (848.32 KB)
Citações na Scopus
1
Tipo de produção
article
Data de publicação
2023
DOI
SciELO
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCIENCE INC
Autores
LOURENCO, Silvia Vanessa
Citação
ANAIS BRASILEIROS DE DERMATOLOGIA, v.98, n.4, p.493-497, 2023
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Lichen planus is an inflammatory disease that can affect both the skin and mucous membranes, including the oral mucosa. There is very little original Brazilian dermatology literature about oral lichen planus. Objective: To describe the clinical, pathological, and treatment data of 201 patients diagnosed with oral lichen planus followed at the Stomatology Outpatient Clinic of Hospital das Clinicas, Universidade de Sao Paulo, from 2003 to 2021. Method: The patients demographic profile, the morpho-topographic features of the lesions, the treatment employed, and the possible presence of squamous cell carcinoma were analyzed. Results: The disease was more common in women over 50 years of age, tending to be chronic, with a large number of cases showing cicatricial sequelae in the mucosa. Topical treatment with potent corticosteroids was shown to be effective in the vast majority of cases. Squamous cell carcinoma in oral lichen planus cicatricial sequelae was observed in eight cases. Study limitations: Retrospective study of medical records, with gaps regarding the filling out of data; unequal observation time among the studied cases. Conclusions: This is the largest Brazilian dermatology series on oral lichen planus. The response to topical corticoid therapy was excellent in the vast majority of cases. The high prevalence of atrophic lesions, demonstrating the chronicity and tissue destruction potential of this disease, may explain the large number of cases of squamous cell carcinoma. (c) 2023 Sociedade Brasileira de Dermatologia.
Palavras-chave
Lichen planus, Oral lichen planus, Oral mucosa
URI
https://observatorio.fm.usp.br/handle/OPI/56053
Referências
  1. Alessi SS, 2013, BRIT J DERMATOL, V168, P257, DOI 10.1111/bjd.12021
  2. Alrashdan MS, 2016, ARCH DERMATOL RES, V308, P539, DOI 10.1007/s00403-016-1667-2
  3. Bazalinski D, 2017, WSPOLCZESNA ONKOL, V21, P197, DOI 10.5114/wo.2017.70109
  4. Cascone M, 2017, INT J DERMATOL, V56, P641, DOI 10.1111/ijd.13571
  5. de Lima Sara-Lia-Goncalves, 2019, J Clin Exp Dent, V11, pe1109, DOI 10.4317/jced.56379
  6. Eisen D, 2002, J AM ACAD DERMATOL, V46, P207, DOI 10.1067/mjd.2002.120452
  7. Ion Daniela I, 2016, Prim Dent J, V5, P40
  8. Olson MA, 2016, CLIN DERMATOL, V34, P495, DOI 10.1016/j.clindermatol.2016.02.023
  9. Roopashree MR, 2010, J ORAL PATHOL MED, V39, P729, DOI 10.1111/j.1600-0714.2010.00946.x
  10. SILVERMAN S, 1985, ORAL SURG ORAL MED O, V60, P30, DOI 10.1016/0030-4220(85)90210-5
  11. Nico MMS, 2011, AN BRAS DERMATOL, V86, P633, DOI 10.1590/S0365-05962011000400002
  12. Takatu CM, 2021, SKIN APPENDAGE DISOR, V7, P54, DOI 10.1159/000511094

Coleções
Artigos e Materiais de Revistas Científicas - FM/MDT
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/06
Artigos e Materiais de Revistas Científicas - ODS/03