Validation of GDI, GPS and GVS for use in Parkinson's disease through evaluation of effects of subthalamic deep brain stimulation and levodopa

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSPECIALI, Danielli Souza
dc.contributor.authorCORREA, Joao Carlos Ferrari
dc.contributor.authorLUNA, Natalia Mariana
dc.contributor.authorBRANT, Rachael
dc.contributor.authorGREVE, Julia Maria D'Andrea
dc.contributor.authorGODOY, Wagner de
dc.contributor.authorBAKER, Richard
dc.contributor.authorLUCARELI, Paulo Roberto Garcia
dc.date.accessioned2014-09-30T14:43:33Z
dc.date.available2014-09-30T14:43:33Z
dc.date.issued2014
dc.description.abstractThe Gait Deviation Index (GDI), Gait Profile Score (GPS) and Gait Variable Scores (GVSs) have been proposed as measures of gait quality and validated for use with children with cerebral palsy. The aim of this study was to extend this validation to people with Parkinson's disease by evaluating the effects of subthalamic deep brain stimulation and levodopa on gait. 16 participants had their gait evaluated with stimulation, medication or a combination of both. The Unified Parkinson's Disease Rating Scale (UPDRS) showed statistically significant differences in agreement with previous studies. The GPS and GDI showed similar treatment effects as did GVS for hip and knee flexion/extension, as assessed with Cohen's d where medium or large. Overall the results suggest that these gait indices are sensitive to treatment in this group of patients and that their use in groups other than children with cerebral palsy is valid.
dc.description.indexMEDLINE
dc.identifier.citationGAIT & POSTURE, v.39, n.4, p.1142-1145, 2014
dc.identifier.doi10.1016/j.gaitpost.2014.01.011
dc.identifier.eissn1879-2219
dc.identifier.issn0966-6362
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/7609
dc.language.isoeng
dc.publisherELSEVIER IRELAND LTD
dc.relation.ispartofGait & Posture
dc.rightsrestrictedAccess
dc.rights.holderCopyright ELSEVIER IRELAND LTD
dc.subjectParkinson's disease
dc.subjectDeep brain stimulation
dc.subjectGait Profile Score
dc.subjectGait Deviation Index
dc.subjectGait
dc.subject.othernucleus stimulation
dc.subject.othergait analysis
dc.subject.otherkinematics
dc.subject.wosNeurosciences
dc.subject.wosOrthopedics
dc.subject.wosSport Sciences
dc.titleValidation of GDI, GPS and GVS for use in Parkinson's disease through evaluation of effects of subthalamic deep brain stimulation and levodopa
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryInglaterra
hcfmusp.affiliation.countryisogb
hcfmusp.author.externalSPECIALI, Danielli Souza:Univ Nove de Julho, Human Mot Anal Lab, Dept Rehabil Sci, BR-01504001 Sao Paulo, Brazil
hcfmusp.author.externalCORREA, Joao Carlos Ferrari:Univ Nove de Julho, Human Mot Anal Lab, Dept Rehabil Sci, BR-01504001 Sao Paulo, Brazil
hcfmusp.author.externalGODOY, Wagner de:Albert Einstein Hosp, Movement Anal Lab, Sao Paulo, Brazil
hcfmusp.author.externalBAKER, Richard:Univ Salford, Sch Hlth Sport & Rehabil Sci, Salford M5 4WT, Lancs, England
hcfmusp.author.externalLUCARELI, Paulo Roberto Garcia:Univ Nove de Julho, Human Mot Anal Lab, Dept Rehabil Sci, BR-01504001 Sao Paulo, Brazil
hcfmusp.citation.scopus19
hcfmusp.contributor.author-fmusphcNATALIA MARIANA SILVA LUNA
hcfmusp.contributor.author-fmusphcRACHAEL BRANT MACHADO RODRIGUES
hcfmusp.contributor.author-fmusphcJULIA MARIA D ANDREA GREVE
hcfmusp.description.beginpage1142
hcfmusp.description.endpage1145
hcfmusp.description.issue4
hcfmusp.description.volume39
hcfmusp.origemWOS
hcfmusp.origem.pubmed24548797
hcfmusp.origem.scopus2-s2.0-84897110934
hcfmusp.origem.wosWOS:000333801400025
hcfmusp.publisher.cityCLARE
hcfmusp.publisher.countryIRELAND
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hcfmusp.scopus.lastupdate2024-05-10
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