Physical activity, muscle strength, and exercise capacity 3 months after severe sepsis and septic shock
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Citações na Scopus
60
Tipo de produção
article
Data de publicação
2015
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER
Citação
INTENSIVE CARE MEDICINE, v.41, n.8, p.1433-1444, 2015
Resumo
To quantify the physical activity in daily life (PADL), muscle strength, and exercise capacity in the short and medium term in survivors of severe sepsis and septic shock. Prospective cohort study with a follow-up from hospital admission to 3 months after hospital discharge. Seventy-two patients admitted to the ICU for severe sepsis or septic shock and a control group of healthy sedentary subjects (n = 50) were enrolled. All patients had their PADL quantified by an accelerometer during their hospital stay and 3 months after. Exercise capacity and handgrip and quadriceps muscle strength were also evaluated. During hospitalization, patients spent the majority of their time inactive in a lying or sitting position (90 +/- A 34 % of daily time). Physical inactivity was partially reduced 3 months after (58 +/- A 20 % of daily time). However, the time patients spent walking was only 63 % of the time reported for healthy subjects. Patients also showed lower movement intensity when compared with controls (2.1 +/- A 0.3 vs 2.5 +/- A 0.4 m/s(2)). At hospital discharge, muscle strength and exercise capacity were approximately 54 % of the predicted value, and these parameters showed significant increase in patients 3 months after (70 % of predicted value). Multivariable analysis demonstrated that the use of systemic corticosteroids and hospitalization time negatively influenced quadriceps strength and exercise capacity at the time of hospital discharge. Our results suggest that survivors of sepsis admitted to the ICU have a substantial reduction in physical activity, exercise capacity, and muscle strength compared to healthy subjects that persist even 3 months after hospital discharge.
Palavras-chave
Intensive care unit, Muscle weakness, Physical activity, Recovery of function, Sepsis, Survivors
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MFT
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HU
Artigos e Materiais de Revistas Científicas - LIM/20
Artigos e Materiais de Revistas Científicas - LIM/51
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HU
Artigos e Materiais de Revistas Científicas - LIM/20
Artigos e Materiais de Revistas Científicas - LIM/51