Parent psychopathology and offspring mental disorders: results from the WHO World Mental Health Surveys

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art_ANDRADE_Parent_psychopathology_and_offspring_mental_disorders_results_from_2012.PDF (372.15 KB)
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182
Tipo de produção
article
Data de publicação
2012
DOI
Scopus
Web of Science
PubMed
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Título do Volume
Editora
ROYAL COLLEGE OF PSYCHIATRISTS
Autores
MCLAUGHLIN, Katie A.
GADERMANN, Anne M.
HWANG, Irving
SAMPSON, Nancy A.
AL-HAMZAWI, Ali
ANGERMEYER, Matthias C.
BENJET, Corina
BROMET, Evelyn J.
BRUFFAERTS, Ronny
Citação
BRITISH JOURNAL OF PSYCHIATRY, v.200, n.4, p.290-299, 2012
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Resumo
Background Associations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity. Aims To examine the associations of parent with respondent disorders. Method Data come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews. Results Although virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle-than low-/lower-middle-income countries, and consistently higher for behaviour (11.0-19.9%) than other (7.1-14.0%) disorders. Conclusions Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.
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https://observatorio.fm.usp.br/handle/OPI/1387
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Coleções
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/23