Comparison of Epidural and Systemic Tramadol for Analgesia Following Ovariohysterectomy
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Citações na Scopus
25
Tipo de produção
article
Data de publicação
2012
Título da Revista
ISSN da Revista
Título do Volume
Editora
AMER ANIMAL HOSPITAL ASSOC
Autores
MASTROCINQUE, Sandra
ALMEIDA, Tatiana F.
TATARUNAS, Angelica C.
IMAGAWA, Viviani H.
MATERA, Julia M.
FANTONI, Denise T.
Citação
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, v.48, n.5, p.310-319, 2012
Resumo
The objective of the study was to compare epidural and systemic tramadol for postoperative analgesia in bitches undergoing ovariohysterectomy. Twenty animals, randomly divided into two groups, received either epidural (EPI) or intramuscular (IM) tramadol (2 mg/kg) 30 min before anesthetic induction. Analgesia, sedation, cardiorespiratory parameters, end-tidal isoflurane, blood catecholamines and cortisol, and arterial blood gases were measured at different time points up to 24 hr after agent administration. There were no differences between the two groups regarding cardiorespiratory parameters, end-tidal isoflurane, and pain scores. Two dogs in the IM and one in the EPI group required supplemental analgesia. Cortisol was increased (P<0.05) at 120 min (3.59 mu g/dL and 3.27 mu g/dL in the IM and EPI groups, respectively) and 240 min (2.45 mu g/dL and 2.54 mu g/dL in the IM and EPI groups, respectively) compared to baseline. Norepinephrine was also increased (P<0.05) at 120 min in both groups compared to baseline values. Epinephrine values were higher (P<0.05) in the IM group compared with the EPI group at 50 min, 120 min, and 1,440 min after tramadol administration. Epidural tramadol is a safe analgesic, but does not appear to have improved analgesic effects compared with IM administration. (J Am Anim Hosp Assoc 2012; 48:310-319. DOI 10.5326/JAAHA-MS-5795)
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Referências
- Almeida TF, 2007, JAVMA-J AM VET MED A, V230, P45, DOI 10.2460/javma.230.1.45
- BARAKA A, 1993, CAN J ANAESTH, V40, P308
- BENSON GJ, 1991, VET SURG, V20, P222, DOI 10.1111/j.1532-950X.1991.tb00340.x
- Block BM, 2003, JAMA-J AM MED ASSOC, V290, P2455, DOI 10.1001/jama.290.18.2455
- Brodbelt DC, 1997, J VET PHARMACOL THER, V20, P284, DOI 10.1046/j.1365-2885.1997.00060.x
- Buback JL, 1996, VET SURG, V25, P380, DOI 10.1111/j.1532-950X.1996.tb01431.x
- Castro DS, 2009, J FELINE MED SURG, V11, P948, DOI 10.1016/j.jfms.2009.04.009
- CHURCH DB, 1994, RES VET SCI, V56, P129, DOI 10.1016/0034-5288(94)90211-9
- DAY TK, 1995, VET SURG, V24, P522, DOI 10.1111/j.1532-950X.1995.tb01366.x
- Deneuche AJ, 2004, VET SURG, V33, P650, DOI 10.1111/j.1532-950X.2004.04088.x
- Duthie DJR, 1998, BRIT J ANAESTH, V81, P51
- Firth AM, 1999, J AM VET MED ASSOC, V214, P651
- Franceschini D, 1999, PROG NEURO-PSYCHOPH, V23, P485, DOI 10.1016/S0278-5846(99)00010-X
- George MJ, 2006, ANAESTHESIA, V61, P659, DOI 10.1111/j.1365-2044.2006.04713.x
- Golder F. J., 1998, Journal of Veterinary Anaesthesia, V25, P52
- Gunes Y, 2004, PEDIATR ANESTH, V14, P324, DOI 10.1046/j.1460-9592.2003.01214.x
- Halfpenny DM, 1999, BRIT J ANAESTH, V83, P909
- Hansen B, 1997, SEMIN VET MED SURG, V12, P61
- Hellyer PW, 2007, LUMB JONES VET ANEST, P31
- Hopkins D, 1998, CAN J ANAESTH, V45, P435
- James MFM, 1996, ANESTH ANALG, V83, P87, DOI 10.1097/00000539-199607000-00015
- Jones RS, 2001, VET J, V161, P123, DOI 10.1053/tvjl.2000.0528
- KRSTULOVIC AM, 1982, J CHROMATOGR, V229, P1, DOI 10.1016/S0378-4347(00)86033-8
- LIN HC, 1993, AM J VET RES, V54, P1721
- Marucio RL, 2008, AM J VET RES, V69, P854, DOI 10.2460/ajvr.69.7.854
- Mastrocinque S, 2003, VET ANAESTH ANALG, V30, P220, DOI 10.1046/j.1467-2995.2003.00090.x
- McMillan CJ, 2008, CAN J VET RES, V72, P325
- Natalini CC, 2000, AM J VET RES, V61, P1579, DOI 10.2460/ajvr.2000.61.1579
- Ozcengiz D, 2001, PAEDIATR ANAESTH, V11, P459, DOI 10.1046/j.1460-9592.2001.00694.x
- Pascoe P, 1997, SEMIN VET MED SURG, V12, P94
- RAWLINGS CA, 1989, VET SURG, V18, P255, DOI 10.1111/j.1532-950X.1989.tb01081.x
- Seddighi MR, 2009, VET ANAESTH ANALG, V36, P334, DOI 10.1111/j.1467-2995.2009.00468.x
- Siddik-Sayyid S, 1999, CAN J ANAESTH, V46, P731
- Singh B, 2006, J CARDIOTHOR VASC AN, V20, P758
- Singh B, 2006, J CARDIOTHOR VASC AN, V20, P757, DOI 10.1053/j.jvca.2006.04.009
- Slover RB, 1996, REGIONAL ANESTHESIA, P143
- STEFFEY EP, 1977, AM J VET RES, V38, P1833
- Troncy E, 2002, J AM VET MED ASSOC, V221, P666, DOI 10.2460/javma.2002.221.666
- VALVERDE A, 1991, AM J VET RES, V52, P505
- Vercauteren MP, 1999, EUR J PAIN-LONDON, V3, P205, DOI 10.1016/S1090-3801(99)90047-2
- Vettorato E, 2010, VET J, V183, P310, DOI 10.1016/j.tvjl.2008.11.002
- Yavuz L, 2004, EUR J GYNAECOL ONCOL, V25, P215