Design and baseline characteristics of a coronary heart disease prospective cohort: two-year experience from the strategy of registry of acute coronary syndrome study (ERICO study)

OBJECTIVES: To describe the ERICO study (Strategy of Registry of Acute Coronary Syndrome), a prospective cohort to investigate the epidemiology of acute coronary syndrome. METHODS: The ERICO study, which is being performed at a secondary general hospital in Sao Paulo, Brazil, is enrolling consecutive acute coronary syndrome patients who are 35 years old or older. The sociodemographic information, medical assessments, treatment data and blood samples are collected at admission. After 30 days, the medical history is updated, and additional blood and urinary samples are collected. In addition, a retinography, carotid intima-media thickness, heart rate variability and pulse-wave velocity are performed. Questionnaires about food frequency, physical activity, sleep apnea and depression are also applied. At six months and annually after an acute event, information is collected by telephone. RESULTS: From February 2009 to September 2011, 738 patients with a diagnosis of an acute coronary syndrome were enrolled. Of these, 208 (28.2%) had ST-elevation myocardial infarction (STEMI), 288 (39.0%) had non-ST-elevation myocardial infarction (NSTEMI) and 242 (32.8%) had unstable angina (UA). The mean age was 62.7 years, 58.5% were men and 77.4% had 8 years or less of education. The most common cardiovascular risk factors were hypertension (76%) and sedentarism (73.4%). Only 29.2% had a prior history of coronary heart disease. Compared with the ST-elevation myocardial infarction subgroup, the unstable angina and non-ST-elevation myocardial infarction patients had higher frequencies of hypertension, diabetes, prior coronary heart disease (p < 0.001) and dyslipidemia (p = 0.03). Smoking was more frequent in the ST-elevation myocardial infarction patients (p = 0.006). CONCLUSIONS: Compared with other hospital registries, our findings revealed a higher burden of CV risk factors and less frequent prior CHD history.

Palavras-chave

Coronary Acute Syndrome, Registries

URI

https://observatorio.fm.usp.br/handle/OPI/1781

Referências

Craig CL, 2003, MED SCI SPORT EXER, V35, P1381, DOI 10.1249/01.MSS.0000078924.61453.FB
Goodman SG, 2009, AM HEART J, V158, P193, DOI 10.1016/j.ahj.2009.06.003
Gunter N, 1997, J S C Med Assoc, V93, P177
Lanas F, 2007, CIRCULATION, V115, P1067, DOI 10.1161/CIRCULATIONAHA.106.633552
Lichtman JH, 2008, CIRCULATION, V118, P1768, DOI 10.1161/CIRCULATIONAHA.108.190769
Luepker RV, 2003, CIRCULATION, V108, P2543, DOI 10.1161/01.CIR.0000100560.46946.EA
Matsudo S, 2001, REV BRAS ATIV FIS SA, V6, P5
Ministerio da Saude do Brasil e Secretaria Municipal da Saude da Cidade de Sao Paulo, INF SAUD PROD HOSP
Netzer NC, 1999, ANN INTERN MED, V131, P485
Nicolau JC, 2012, ARQ BRAS CARDIOL, V98, P282, DOI 10.1590/S0066-782X2012000400001
Prefeitura do Municipio de Sao Paulo, BUT REG OEST SUM DAD
Prefeitura do Municipio de Sao Paulo, DAD DEM DISTR PERT S
Santos ES, 2006, ARQ BRAS CARDIOL, V87, P597
Sichieri R, 1998, NUTR RES, V18, P1649, DOI 10.1016/S0271-5317(98)00151-1
Teo KK, 2006, LANCET, V368, P647, DOI 10.1016/S0140-6736(06)69249-0
Thygesen K, 2007, EUR HEART J, V28, P2525
TUNSTALL-PEDOE H, 1988, Journal of Clinical Epidemiology, V41, P105
[Anonymous], 2001, AM HEART J, V141, P190

Coleções

Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/13
Artigos e Materiais de Revistas Científicas - LIM/51
Artigos e Materiais de Revistas Científicas - ODS/03

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