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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | MORELL-AZANZA, Lydia | - |
dc.contributor.author | GARCIA-CALZON, Sonia | - |
dc.contributor.author | RENDO-URTEAGA, Tara | - |
dc.contributor.author | MARTIN-CALVO, Nerea | - |
dc.contributor.author | CHUECA, Maria | - |
dc.contributor.author | MARTINEZ, Jose Alfredo | - |
dc.contributor.author | AZCONA-SANJULIAN, Maria Cristina | - |
dc.contributor.author | MARTI, Amelia | - |
dc.date.accessioned | 2017-08-17T19:20:43Z | - |
dc.date.available | 2017-08-17T19:20:43Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | PEDIATRIC DIABETES, v.18, n.5, p.392-398, 2017 | - |
dc.identifier.issn | 1399-543X | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/21455 | - |
dc.description.abstract | Background and aimsThe oxidation of low-density lipoprotein (LDL) cholesterol particles is an early atherogeninic event. Obese pediatric populations have higher levels of oxidized LDL (oxLDL) than normal weight children. The aim of this study was to evaluate the effect of a weight loss program on the biochemical profile and oxLDL levels in Spanish obese children and adolescents. MethodsForty obese children (mean age 11 years, 51% boys) followed a 10-week weight loss program. They were dichotomized at the median of body mass index-standard deviation score (BMI-SDS) change, as high (HR) and low responders (LR) after the intervention. The intervention included a moderate energy-restricted diet, nutritional education, and family involvement. Anthropometric and biochemical measurements were performed at the beginning and during the follow up. A cardiometabolic risk score (CMS) was calculated considering metabolic risk factors. ResultsHigher baseline oxLDL levels were associated with a higher CMS in obese children (P<.001). After the intervention, oxLDL significantly decreased in the HR group. Moreover, a positive correlation between changes in oxLDL and BMI-SDS (r=0.385, P=.015) was found after the weight loss program. Interestingly, multiple-adjusted regression models showed an association between changes in total cholesterol [B: 0.127, 95% confidence interval (CI): 0.06 to 0.20] and LDL-cholesterol (B: 0.173, 95% CI: 0.08 to 0.26) with changes in oxLDL. ConclusionsHigher baseline oxLDL levels were associated with a higher CMS in obese children. After the weight loss program, a decrease in oxLDL levels was found in HR subjects and the oxLDL levels were associated with BMI-SDS and cholesterol levels. | - |
dc.description.sponsorship | Navarra Goverment [PI 54/2009] | - |
dc.description.sponsorship | PIUNA | - |
dc.description.sponsorship | CIBERobn (project CIBER) [CB06/03/1017] | - |
dc.language.iso | eng | - |
dc.publisher | WILEY | - |
dc.relation.ispartof | Pediatric Diabetes | - |
dc.rights | restrictedAccess | - |
dc.subject | BMI-SDS | - |
dc.subject | dietary intervention | - |
dc.subject | LDL-cholesterol | - |
dc.subject | pediatrics | - |
dc.subject.other | oxidative stress | - |
dc.subject.other | cardiovascular-disease | - |
dc.subject.other | metabolic syndrome | - |
dc.subject.other | childhood obesity | - |
dc.subject.other | ldl | - |
dc.subject.other | overweight | - |
dc.subject.other | consumption | - |
dc.subject.other | healthy | - |
dc.subject.other | markers | - |
dc.subject.other | diet | - |
dc.title | Serum oxidized low-density lipoprotein levels are related to cardiometabolic risk and decreased after a weight loss treatment in obese children and adolescents | - |
dc.type | article | - |
dc.rights.holder | Copyright WILEY | - |
dc.identifier.doi | 10.1111/pedi.12405 | - |
dc.identifier.pmid | 27435258 | - |
dc.subject.wos | Endocrinology & Metabolism | - |
dc.subject.wos | Pediatrics | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | MORELL-AZANZA, Lydia:Univ Navarra, Dept Nutr Food Sci & Physiol, Pamplona, Spain; Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain | - |
hcfmusp.author.external | GARCIA-CALZON, Sonia:Univ Navarra, Dept Nutr Food Sci & Physiol, Pamplona, Spain; Lund Univ, Epigenet & Diabet Unit, Ctr Diabet, Malmo, Sweden; Scania Univ Hosp, Dept Clin Sci, CRC, Malmo, Sweden | - |
hcfmusp.author.external | MARTIN-CALVO, Nerea:Univ Navarra, Sch Med, Dept Prevent Med & Publ Hlth, Pamplona, Spain; Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain | - |
hcfmusp.author.external | CHUECA, Maria:Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain; Complejo Hosp Navarra, Paediat Endocrinol Unit, Pamplona, Spain | - |
hcfmusp.author.external | MARTINEZ, Jose Alfredo:Univ Navarra, Dept Nutr Food Sci & Physiol, Pamplona, Spain; Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain; Inst Hlth Carlos III, Ctr Biomed Res Physiopathol Obes & Nutr CIBEROBN, Madrid, Spain | - |
hcfmusp.author.external | AZCONA-SANJULIAN, Maria Cristina:Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain; Clin Univ Navarra, Paediat Endocrinol Unit, Dept Paediat, Pamplona, Spain | - |
hcfmusp.author.external | MARTI, Amelia:Univ Navarra, Dept Nutr Food Sci & Physiol, Pamplona, Spain; Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain; Inst Hlth Carlos III, Ctr Biomed Res Physiopathol Obes & Nutr CIBEROBN, Madrid, Spain | - |
hcfmusp.description.beginpage | 392 | - |
hcfmusp.description.endpage | 398 | - |
hcfmusp.description.issue | 5 | - |
hcfmusp.description.volume | 18 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84978698397 | - |
hcfmusp.origem.id | WOS:000404902100009 | - |
hcfmusp.publisher.city | HOBOKEN | - |
hcfmusp.publisher.country | USA | - |
hcfmusp.relation.reference | Albuali Waleed H, 2014, World J Clin Pediatr, V3, P6, DOI 10.5409/wjcp.v3.i1.6 | - |
hcfmusp.relation.reference | Chae JS, 2013, NUTR RES, V33, P195, DOI 10.1016/j.nutres.2013.01.005 | - |
hcfmusp.relation.reference | Codoner-Franch P, 2011, ATHEROSCLEROSIS, V215, P475, DOI 10.1016/j.atherosclerosis.2010.12.035 | - |
hcfmusp.relation.reference | Cole TJ, 2000, BRIT MED J, V320, P1240, DOI 10.1136/bmj.320.7244.1240 | - |
hcfmusp.relation.reference | de la Iglesia R, 2013, INT J MOL SCI, V14, P6903, DOI 10.3390/ijms14046903 | - |
hcfmusp.relation.reference | Galcheva SV, 2011, EUR J ENDOCRINOL, V164, P553, DOI 10.1530/EJE-10-1124 | - |
hcfmusp.relation.reference | Galle J, 2006, ATHEROSCLEROSIS, V185, P219, DOI 10.1016/j.atherosclerois.2005.10.005 | - |
hcfmusp.relation.reference | Ibero-Baraibar I, 2014, NUTR METAB CARDIOVAS, V24, P416, DOI 10.1016/j.numecd.2013.09.017 | - |
hcfmusp.relation.reference | Kelishadi R, 2008, CLIN CHEM, V54, P147, DOI 10.1373/clinchem.2007.089953 | - |
hcfmusp.relation.reference | Kelly AS, 2010, PEDIATR DIABETES, V11, P552, DOI 10.1111/j.1399-5448.2009.00640.x | - |
hcfmusp.relation.reference | Linna MS, 2007, INT J OBESITY, V31, P245, DOI 10.1038/sj.ijo.0803413 | - |
hcfmusp.relation.reference | Loffredo L, 2012, J PEDIATR-US, V161, P1004, DOI 10.1016/j.jpeds.2012.05.042 | - |
hcfmusp.relation.reference | Maiolino G, 2013, MEDIAT INFLAMM, DOI 10.1155/2013/714653 | - |
hcfmusp.relation.reference | Marin MT, 2015, J DIABETES COMPLICAT, V29, P679, DOI 10.1016/j.jdiacomp.2015.03.015 | - |
hcfmusp.relation.reference | Matusik P, 2015, BIOMED RES INT, DOI 10.1155/2015/315747 | - |
hcfmusp.relation.reference | McCrindle BW, 2015, CAN J CARDIOL, V31, DOI 10.1016/j.cjca.2014.08.017 | - |
hcfmusp.relation.reference | Nascimento H, 2015, DIABETOL METAB SYNDR, V23, P4 | - |
hcfmusp.relation.reference | Okur I, 2013, J PEDIATR ENDOCR MET, V26, P657, DOI 10.1515/jpem-2012-0374 | - |
hcfmusp.relation.reference | Rendo-Urteaga T, 2014, EUR J PEDIATR, V173, P609, DOI 10.1007/s00431-013-2229-7 | - |
hcfmusp.relation.reference | Rendo-Urteaga T, 2015, BRIT J NUTR, V113, P331, DOI 10.1017/S0007114514003584 | - |
hcfmusp.relation.reference | Rendo-Urteaga T, 2013, METABOLISM, V62, P1429, DOI 10.1016/j.metabol.2013.05.011 | - |
hcfmusp.relation.reference | Sanchez-Cruz JJ, 2013, REV ESP CARDIOL, V66, P371, DOI [10.1016/j.rec.2012.10.012, 10.1016/j.recesp.2012.10.016] | - |
hcfmusp.relation.reference | Sanders RH, 2015, EUR J PEDIATR, V174, P715, DOI 10.1007/s00431-015-2551-3 | - |
hcfmusp.relation.reference | Schindhelm RK, 2009, CLIN CHEM, V55, P1462, DOI 10.1373/clinchem.2009.126029 | - |
hcfmusp.relation.reference | Schofield W N, 1985, Hum Nutr Clin Nutr, V39 Suppl 1, P5 | - |
hcfmusp.relation.reference | Shin MJ, 2006, INT J OBESITY, V30, P1529, DOI 10.1038/sj.ijo.0803304 | - |
hcfmusp.relation.reference | Skinner AC, 2015, NEW ENGL J MED, V373, P1307, DOI 10.1056/NEJMoa1502821 | - |
hcfmusp.relation.reference | Sobradillo A, FUNDACION CURVAS TAB | - |
hcfmusp.relation.reference | Sociedad Espanola de Nutricion Comunitaria, GUIA AL SAL | - |
hcfmusp.relation.reference | Stringer DM, 2009, PEDIATR DIABETES, V10, P269, DOI 10.1111/j.1399-5448.2008.00473.x | - |
hcfmusp.relation.reference | Tjonna AE, 2009, CLIN SCI, V116, P317, DOI 10.1042/CS20080249 | - |
hcfmusp.relation.reference | Tumova E, 2013, J OBES, V2013, P1 | - |
hcfmusp.relation.reference | Yngve A, 2008, EUR J PUBLIC HEALTH, V18, P126, DOI 10.1093/eurpub/ckm099 | - |
dc.description.index | MEDLINE | - |
dc.identifier.eissn | 1399-5448 | - |
hcfmusp.citation.scopus | 14 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/Outros Artigos e Materiais de Revistas Científicas - ODS/03 |
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