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https://observatorio.fm.usp.br/handle/OPI/24514| Title: | Serum Levels of Proinflammatory Cytokines in Painful Knee Osteoarthritis and Sensitizationd |
| Authors: | IMAMURA, Marta; EZQUERRO, Fernando; ALFIERI, FabioMarcon; BOAS, Lucy Vilas; TOZETTO-MENDOZA, Tania Regina; CHEN, Janini; OZCAKAR, Levent; ARENDT-NIELSEN, Lars; BATTISTELLA, Linamara Rizzo |
| Citation: | INTERNATIONAL JOURNAL OF INFLAMMATION, article ID UNSP 329792, 8p, 2015 |
| Abstract: | Osteoarthritis (OA) is themost common joint disorder in the world. Among themechanisms involved in osteoarthritis, biomarkers (cytokines profile) may be related to pain and pain intensity, functional capacity, and pressure pain thresholds (PPT). Thus, the study of these relationships may offer useful information about pathophysiology and associated mechanisms involved in osteoarthritis. Therefore, the objective of this study was to investigate the seric concentration of pro (IL-6, IL-8, and TNF-alpha) and anti-inflammatory (IL-10) cytokines in patients with painful knee osteoarthritis and to correlate the levels of these biomarkers with the patients' functional capacity and pressure pain threshold (PPT) values. |
| Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MLS Artigos e Materiais de Revistas Científicas - HC/IMREA Artigos e Materiais de Revistas Científicas - IMT Artigos e Materiais de Revistas Científicas - LIM/40 Artigos e Materiais de Revistas Científicas - LIM/52 |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| art_IMAMURA_Serum_Levels_of_Proinflammatory_Cytokines_in_Painful_Knee_2015.PDF | publishedVersion(English) | 1.27 MB | Adobe PDF |  View/Open |
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