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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
dc.contributor.author | ZUMARRAGA, Juan Pablo | |
dc.contributor.author | BATISTA, Felipe Augusto Ribeiro | |
dc.contributor.author | BAPTISTA, Andre Mathias | |
dc.contributor.author | CAIERO, Marcelo Tadeu | |
dc.contributor.author | MARTINO, Luis Pablo De La Rosa | |
dc.contributor.author | CAMARGO, Olavo Pires De | |
dc.date.accessioned | 2019-01-17T13:35:04Z | |
dc.date.available | 2019-01-17T13:35:04Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | ACTA ORTOPEDICA BRASILEIRA, v.26, n.5, p.320-324, 2018 | |
dc.identifier.issn | 1413-7852 | |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/30003 | |
dc.description.abstract | Objective: Myxofibrosarcoma (MFS) is a common soft tissue sarcoma (STS) that affects the extremities in elderly patients. The objective was to analyze the prognostic factors and outcomes of patients with MFS treated at a single institution. Methods: We retrospectively reviewed the records of 75 patients with MFS. We compared age, sex, tumor size and location, grade and stage of the disease. Median age was 49.7 years (range, 1 to 88 y). Location: upper extremity (25.4%), lower extremity (66.6%) and pelvis (8%). Patients had high-grade tumors in 46.7% of the reports. Margins were negative in 76% of the cases. Bivariate Cox regression analysis was used to determine associations between clinical and treatment factors with local recurrence (LR). Results: Median follow-up time was 30.7 months (range, 1.8 to 383.8 m). We found 26.7% of LR. Distant metastasis (DM) was reported in 27 (36%) patients. Lung was the most common site of DM, reported in 92.6% of patients. Overall survival (OS) with metastasis was 21.2 months (range, 4.8 to 114.8 m). Predictors of OS were grade, LR (hazard ratio [FIR] 5.13, 95% confidence interval, 2.15-12.24, P <0.001), and DM (HR 540.97, 95% confidence interval, 5.04-58112.03, P< 0.001). Conclusions: Tumor grade, LR, positive margins and DM were significant predictors of poor OS prognosis. | eng |
dc.language.iso | eng | |
dc.publisher | ATHA COMUNICACAO & EDITORA | eng |
dc.relation.ispartof | Acta Ortopedica Brasileira | |
dc.rights | openAccess | eng |
dc.subject | Sarcoma | eng |
dc.subject | Excision margins | eng |
dc.subject | Recurrence | eng |
dc.subject | Radiotherapy | eng |
dc.subject | Neoplasm metastasis | eng |
dc.subject.other | high-grade myxofibrosarcoma | eng |
dc.subject.other | sarcoma | eng |
dc.subject.other | variant | eng |
dc.subject.other | impact | eng |
dc.title | PROGNOSTIC FACTORS IN PATIENTS WITH APPENDICULAR MYXOFIBROSARCOMA | eng |
dc.type | article | eng |
dc.rights.holder | Copyright ATHA COMUNICACAO & EDITORA | eng |
dc.identifier.doi | 10.1590/1413-785220182605208644 | |
dc.identifier.pmid | 30464713 | |
dc.subject.wos | Orthopedics | eng |
dc.type.category | original article | eng |
dc.type.version | publishedVersion | eng |
hcfmusp.description.beginpage | 320 | |
hcfmusp.description.endpage | 324 | |
hcfmusp.description.issue | 5 | |
hcfmusp.description.volume | 26 | |
hcfmusp.origem | WOS | |
hcfmusp.origem.id | WOS:000448984100007 | |
hcfmusp.origem.id | 2-s2.0-85056165998 | |
hcfmusp.origem.id | SCIELO:S1413-78522018000500320 | |
hcfmusp.publisher.city | SAO PAULO SP | eng |
hcfmusp.publisher.country | BRAZIL | eng |
hcfmusp.relation.reference | Bonvalot S, 2017, ANN SURG ONCOL, V24, P194, DOI 10.1245/s10434-016-5462-2 | eng |
hcfmusp.relation.reference | Emori M, 2015, J SURG ONCOL, V111, P975, DOI 10.1002/jso.23934 | eng |
hcfmusp.relation.reference | Hoang Kevin, 2015, Iowa Orthop J, V35, P181 | eng |
hcfmusp.relation.reference | Hong NJL, 2013, ANN SURG ONCOL, V20, P80, DOI 10.1245/s10434-012-2572-3 | eng |
hcfmusp.relation.reference | Imanishi J, 2016, ANTICANCER RES, V36, P2339 | eng |
hcfmusp.relation.reference | Kikuta K, 2017, JPN J CLIN ONCOL, V47, P334, DOI 10.1093/jjco/hyw199 | eng |
hcfmusp.relation.reference | le Grange F, 2014, EJSO-EUR J SURG ONC, V40, P394, DOI 10.1016/j.ejso.2014.01.011 | eng |
hcfmusp.relation.reference | Neagu TP, 2017, ROM J MORPHOL EMBRYO, V58, P603 | eng |
hcfmusp.relation.reference | Odei B, 2017, AM J CLIN ONCOL | eng |
hcfmusp.relation.reference | Quimby A, 2017, J ORAL MAXILLOFAC SU, V75 | eng |
hcfmusp.relation.reference | Randall RL, 2007, ORTHOPAEDIC KNOWLEDG, P277 | eng |
hcfmusp.relation.reference | Sakamoto A, 2014, SKELETAL RADIOL, V43, P1487, DOI 10.1007/s00256-014-1914-6 | eng |
hcfmusp.relation.reference | Sambri A, 2016, EJSO-EUR J SURG ONC, V42, P1042, DOI 10.1016/j.ejso.2016.05.015 | eng |
hcfmusp.relation.reference | Sawamura C, 2010, CLIN ORTHOP RELAT R, V468, P3019, DOI 10.1007/s11999-010-1398-1 | eng |
hcfmusp.relation.reference | Scoccianti G, 2016, J SURG ONCOL, V114, P50, DOI 10.1002/jso.24250 | eng |
hcfmusp.relation.reference | Silverstein E, 2007, ORTHOPAEDIC KNOWLEDG, P289 | eng |
hcfmusp.relation.reference | Stacchiotti S, 2012, CANCER-AM CANCER SOC, V118, P5857, DOI 10.1002/cncr.27624 | eng |
hcfmusp.relation.reference | Tsuchie H, 2017, UPSALA J MED SCI, V122, P190, DOI 10.1080/03009734.2017.1356404 | eng |
hcfmusp.relation.reference | WEISS SW, 1977, CANCER, V39, P1672, DOI 10.1002/1097-0142(197704)39:4<1672::AID-CNCR2820390442>3.0.CO;2-C | eng |
dc.description.index | PubMed | eng |
dc.identifier.eissn | 1809-4406 | |
hcfmusp.citation.scopus | 4 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MOT Artigos e Materiais de Revistas Científicas - HC/IOT Artigos e Materiais de Revistas Científicas - LIM/41 Artigos e Materiais de Revistas Científicas - ODS/03 |
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