Cryptococcosis in Patients with Hematologic Diseases

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art_GUARANA_Cryptococcosis_in_Patients_with_Hematologic_Diseases_2018.PDF (417.89 KB)
Citações na Scopus
2
Tipo de produção
article
Data de publicação
2018
DOI
Scopus
Web of Science
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER
Autores
GUARANA, Mariana
NUCCI, Marcio
Citação
CURRENT FUNGAL INFECTION REPORTS, v.12, n.4, p.187-194, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Purpose of Review In this paper, we reviewed the epidemiology, diagnosis, and treatment of cryptococcosis in patients with hematologic malignancies. We reviewed all case series of cryptococcosis in different hematologic conditions, and looked at epidemiologic trends considering the new antineoplastic drugs introduced in the treatment of hematologic malignancies. Recent Findings Case series of cryptococcosis in patients with hematologic malignancies are scarce. We identified an increase in the proportion of cases of cryptococcosis occurring in patients with hematologic malignancies, and many case reports of cryptococcosis in patients receiving ibrutinib, a Bruton kinase inhibitor used in the treatment of chronic lymphoproliferative diseases. Summary Cryptococcosis is uncommon in patients with hematologic malignancies, but its occurrence may be associated with poor outcome. Hematologists should be aware of this complication if patients develop neurologic symptoms or present with pulmonary infiltrates that do not improve with antibiotics.
Palavras-chave
Cryptococcosis, Cryptococcus, Hematologic malignancy, Epidemiology, Diagnosis, Treatment
URI
https://observatorio.fm.usp.br/handle/OPI/30147
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Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - IMT
Artigos e Materiais de Revistas Científicas - LIM/49