Specific characteristics of urethral strictures in a developing country (Brazil)

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Citações na Scopus
5
Tipo de produção
article
Data de publicação
2019
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER
Autores
ASTOLFI, R. H.
LEBANI, B. R.
KREBS, R. K.
DIAS-FILHO, A. C.
CAVALCANTI, A. G.
XIMENES, S. F.
BERTOLLA, R. P.
GEMINIANI, Julio J.
Citação
WORLD JOURNAL OF UROLOGY, v.37, n.4, p.661-666, 2019
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
PurposeEvaluate the main etiologies and clinical characteristics of male urethral stricture disease (USD) in Brazil.MethodsThis multicentric study was performed using retrospective data collected from six Brazilian referral centers of urethral reconstruction. The database comprised data from 899 patients with USD who had undergone surgical treatment from 2008 to 2018. Age, stricture site and primary stricture etiology were identified for each patient.ResultsThe mean age was 52.1316.9years. The most common etiology was iatrogenic (43.4%), followed by idiopathic (21.7%), trauma (21.5%) and inflammatory (13.7%). Of the iatrogenic causes, 59% were secondary to urethral instrumentation (60% by urethral catheterization and 40% by transurethral procedures), 24.8% by other procedures (prostatectomy, radiotherapy, postectomy) and 16.2% by failed hypospadia repairs. Pelvic fracture urethral distraction injuries were responsible for most of the trauma-related strictures (62.7%). When stratified by age, the most common stricture etiology was trauma in the 0-39years old group (42.8%), idiopathic in the 40-59years old group (32.4%) and iatrogenic in patients over 60years old (68%). In regard to the stricture site, 80% presented with an anterior urethral stricture and 20% with a posterior stenosis. In the anterior stenosis group, the most common stricture site was bulbar (39.5%).Conclusion p id=Par4 In Brazil, as in many developed countries, the most common cause of urethral stricture diseases is iatrogenic, especially urethral catheterization. These findings emphasize the need of a careful urethral manipulation and a better training of healthcare professionals. Trauma is still responsible for a great proportion of strictures and inflammatory etiologies are now less frequently observed.
Palavras-chave
Urethral stricure, Ethiology, Iatrogenic disease, Urinary catheterization, Lichen sclerosus, Urethritis
URI
https://observatorio.fm.usp.br/handle/OPI/31897
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Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/55
Artigos e Materiais de Revistas Científicas - ODS/03