Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil

Abstract By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-Sangue/Hemocentro de São Paulo (FPS-HSP). Three seronegative HIV-viremic donations were detected. The NAT yield rate per million donations was 3.34 for HIV, and the acute HIV-1 infections detected are described, followed by a brief review of the situation in Brazil.

Palavras-chave

HIV, NAT-HIV, Window period

URI

https://observatorio.fm.usp.br/handle/OPI/32045

Referências

Alencar CS, 2013, JAIDS-J ACQ IMM DEF, V63, P387, DOI 10.1097/QAI.0b013e31828ff979
Barreto CC, 2006, JAIDS-J ACQ IMM DEF, V41, P338
Busch MP, 2003, JAMA-J AM MED ASSOC, V289, P959, DOI 10.1001/jama.289.8.959
Candotti D, 2004, J VIROL METHODS, V118, P39, DOI [10.1016/S0166-0934(04)00019-9, 10.1016/j.jviromet.2004.01.017]
Delwart E, 2012, J INFECT DIS, V205, P875, DOI 10.1093/infdis/jir862
Goncalez T, 2010, TRANSFUSION, V50, P1806, DOI 10.1111/j.1537-2995.2010.02650.x
Roth WK, 2012, VOX SANG, V102, P82, DOI 10.1111/j.1423-0410.2011.01506.x
Sabino EC, 2012, TRANSFUSION, V52, P870, DOI 10.1111/j.1537-2995.2011.03344.x
Salles NA, 2013, TRANSFUSION, V53, P2593, DOI 10.1111/trf.12316

Coleções

Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - IMT
Artigos e Materiais de Revistas Científicas - LIM/05
Artigos e Materiais de Revistas Científicas - LIM/31
Artigos e Materiais de Revistas Científicas - ODS/03

Página do item completo