Analysis of inflammatory and metabolic biomarkers in patients submitted to abdominoplasty after bariatric surgery

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Citações na Scopus
5
Tipo de produção
article
Data de publicação
2019
Título da Revista
ISSN da Revista
Título do Volume
Editora
ACTA CIRURGICA BRASILEIRA
Citação
ACTA CIRURGICA BRASILEIRA, v.34, n.5, article ID UNSP e201900506, 6p, 2019
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Unidades Organizacionais
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Resumo
Purpose: To evaluate the serum variations of Interleukins (Il) and CPR of abdominoplashes in post-bariatric patients and, to equate the homeostasis (HOMA) from the variations of glycemia and insulin to evolute the metabolic modifications. Methods: Fourteen women were submitted to abdominoplasties with weight loss after a gastroplasty. Levels of IL4, IL6, IL10, CRP, glycemia and insulin were obtained during the preoperative, trans-operative, 24 hours post, 7th and 14th postoperative days. Results: The IL4 was higher at 24 hours post-surgery, and after a moderate decrease, it remained high until the 14th day. The IL6 CRP had an expressive increase during the trans-operative period. The CRP remained high, and the IL6 decreased on the 7th and 14th days. The IL10 increased during the transoperative period, and it posteriorly decreased to lower levels in comparison to the pre-operative period. The already increased glycemia during the pre-operative period was even higher during the trans-operative and then, returned to preliminary values on the 7th and 14th days after surgery. The HOMA accompanied the insulin. Conclusion: The inflammatory and glycemic serum levels decrease after abdominiplasty in obese post-bariatric patients.
Palavras-chave
Obesity, Metabolic Syndrome, Interleukins, Homeostasis, Abdominoplasty
Referências
  1. CASTELL JV, 1988, FEBS LETT, V232, P347, DOI 10.1016/0014-5793(88)80766-X
  2. Chiappetta S, 2018, OBES SURG, V28, P3028, DOI 10.1007/s11695-018-3320-y
  3. Dandona P, 2004, TRENDS IMMUNOL, V25, P4, DOI 10.1016/j.it.2003.10.013
  4. Esposito K, 2006, PLAST RECONSTR SURG, V118, P1048, DOI 10.1097/01.prs.0000232281.49432.ce
  5. Freitas WR, 2018, OBES SURG, V28, P1931, DOI 10.1007/s11695-017-3104-9
  6. Gonzalez-Ortiz M, 2002, HORM METAB RES, V34, P446, DOI 10.1055/s-2002-33603
  7. Gomez FI, 2016, NUTR HOSP, V33, P1340, DOI 10.20960/nh.793
  8. Lyon CJ, 2003, ENDOCRINOLOGY, V144, P2195, DOI 10.1210/en.2003-0285
  9. Rizzo MR, 2005, CLIN ENDOCRINOL, V63, P253, DOI 10.1111/j.1365-2265.2005.02337.x
  10. Sippel C, 2014, REV ATENCAO SAUDE, V12, P48
  11. Trayhurn P, 2001, P NUTR SOC, V60, P329, DOI 10.1079/PNS200194
  12. Tsao CH, 2014, J LIPID RES, V55, P385, DOI 10.1194/jlr.M041392
  13. Visser M, 1999, JAMA-J AM MED ASSOC, V282, P2131, DOI 10.1001/jama.282.22.2131
  14. Vozarova B, 2001, OBES RES, V9, P414, DOI 10.1038/oby.2001.54
  15. Wensveen FM, 2015, EUR J IMMUNOL, V45, P2446, DOI 10.1002/eji.201545502