Attention-deficit hyperactivity disorder

Carregando...
Imagem de Miniatura
Citações na Scopus
395
Tipo de produção
article
Data de publicação
2020
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCIENCE INC
Autores
POSNER, Jonathan
SONUGA-BARKE, Edmund
Citação
LANCET, v.395, n.10222, p.450-462, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Attention-deficit hyperactivity disorder (ADHD), like other psychiatric disorders, represents an evolving construct that has been refined and developed over the past several decades in response to research into its clinical nature and structure. The clinical presentation and course of the disorder have been extensively characterised. Efficacious medication-based treatments are available and widely used, often alongside complementary psychosocial approaches. However, their effectiveness has been questioned because they might not address the broader clinical needs of many individuals with ADHD, especially over the longer term. Non-pharmacological approaches to treatment have proven less effective than previously thought, whereas scientific and clinical studies are starting to fundamentally challenge current conceptions of the causes of ADHD in ways that might have the potential to alter clinical approaches in the future. In view of this, we first provide an account of the diagnosis, epidemiology, and treatment of ADHD from the perspective of both the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders and the eleventh edition of the International Classification of Diseases. Second, we review the progress in our understanding of the causes and pathophysiology of ADHD on the basis of science over the past decade or so. Finally, using these discoveries, we explore some of the key challenges to both the current models and the treatment of ADHD, and the ways in which these findings can promote new perspectives.
Palavras-chave
Referências
  1. Adler LD, 2010, POSTGRAD MED, V122, P184, DOI 10.3810/pgm.2010.01.2112
  2. [Anonymous], 2013, DIAGN STAT MAN MENT
  3. Asherson P, 2019, J CHILD PSYCHOL PSYC, V60, P333, DOI 10.1111/jcpp.13020
  4. Barbaresi WJ, 2007, J DEV BEHAV PEDIATR, V28, P274, DOI 10.1097/DBP.0b013e3180cabc28
  5. Barker ED, 2018, J CHILD PSYCHOL PSYC, V59, P303, DOI 10.1111/jcpp.12782
  6. Barkley RA, 2002, J CLIN PSYCHIAT, V63, P10
  7. Biederman J, 2003, J CLIN PSYCHIAT, V64, P3
  8. Brown Thomas E, 2008, Curr Psychiatry Rep, V10, P407, DOI 10.1007/s11920-008-0065-7
  9. Buse J, 2013, NEUROSCI BIOBEHAV R, V37, P1069, DOI 10.1016/j.neubiorev.2012.10.004
  10. Bussing R, 2003, J BEHAV HEALTH SER R, V30, P176, DOI 10.1007/BF02289806
  11. Campbell SB, 2014, HDB DEV PSYCHOPATHOL, P427
  12. Canadian ADHD Resource Alliance, 2018, CAN ADHD PRACT GUID
  13. Casey BJ, 2014, BIOL PSYCHIAT, V76, P350, DOI 10.1016/j.biopsych.2014.01.006
  14. Castellanos FX, 2006, TRENDS COGN SCI, V10, P117, DOI 10.1016/j.tics.2006.01.011
  15. Castellanos FX, 1996, ARCH GEN PSYCHIAT, V53, P607
  16. Castells X, 2011, CNS DRUGS, V25, P157, DOI 10.2165/11539440-000000000-00000
  17. Caye A, 2019, Epidemiol Psychiatr Sci, V29, pe37, DOI 10.1017/S2045796019000283
  18. Cha J, 2015, NEUROPSYCHOPHARMACOL, V40, P1717, DOI 10.1038/npp.2015.18
  19. Chacko A, 2013, J CLIN CHILD ADOLESC, V42, P769, DOI 10.1080/15374416.2013.787622
  20. Chang Z, 2019, BIOL PSYCHIAT, V86, P335, DOI 10.1016/j.biopsych.2019.04.009
  21. Chang Z, 2017, JAMA PSYCHIAT, V74, P597, DOI 10.1001/jamapsychiatry.2017.0659
  22. Chang Z, 2014, J CHILD PSYCHOL PSYC, V55, P878, DOI 10.1111/jcpp.12164
  23. Charach A, 2013, CURR PSYCHIAT REP, V15, DOI 10.1007/s11920-013-0371-6
  24. Class QA, 2014, BRIT J PSYCHIAT, V205, P355, DOI 10.1192/bjp.bp.113.143693
  25. Coghill D, 2012, J CHILD PSYCHOL PSYC, V53, P469, DOI 10.1111/j.1469-7610.2011.02511.x
  26. Collishaw S, 2015, J CHILD PSYCHOL PSYC, V56, P370, DOI 10.1111/jcpp.12372
  27. Cooper WO, 2011, NEW ENGL J MED, V365, P1896, DOI 10.1056/NEJMoa1110212
  28. Cortese S, 2018, LANCET PSYCHIAT, V5, P727, DOI 10.1016/S2215-0366(18)30269-4
  29. Cortese S, 2016, J AM ACAD CHILD PSY, V55, P444, DOI 10.1016/j.jaac.2016.03.007
  30. Cortese S, 2015, J AM ACAD CHILD PSY, V54, P164, DOI 10.1016/j.jaac.2014.12.010
  31. Cunill R, 2013, PHARMACOEPIDEM DR S, V22, P961, DOI 10.1002/pds.3473
  32. Daley D, 2018, J CHILD PSYCHOL PSYC, V59, P932, DOI 10.1111/jcpp.12825
  33. Duric NS, 2017, NORD J PSYCHIAT, V71, P386, DOI 10.1080/08039488.2017.1305446
  34. Edlow AG, 2017, PRENATAL DIAG, V37, P95, DOI 10.1002/pd.4932
  35. Elia J, 2018, NAT COMMUN, V9, DOI 10.1038/s41467-017-02244-2
  36. Elia J, 2012, NAT GENET, V44, P78, DOI 10.1038/ng.1013
  37. Fair DA, 2010, BIOL PSYCHIAT, V68, P1084, DOI 10.1016/j.biopsych.2010.07.003
  38. Faraone SV, 2010, EUR CHILD ADOLES PSY, V19, P353, DOI 10.1007/s00787-009-0054-3
  39. Faraone SV, 2008, J AM ACAD CHILD PSY, V47, P994, DOI [10.1097/CHI.0b013e31817e0ea7, 10.1097/CHI.ObO13e31817eOea7]
  40. Faraone SV, 2006, PSYCHOL MED, V36, P159, DOI 10.1017/S003329170500471X
  41. Faraone SV, 2005, BIOL PSYCHIAT, V57, P1313, DOI 10.1016/j.biopsych.2004.11.024
  42. Filipek PA, 1997, NEUROLOGY, V48, P589, DOI 10.1212/WNL.48.3.589
  43. Franke B, 2018, EUR NEUROPSYCHOPHARM, V28, P1059, DOI 10.1016/j.euroneuro.2018.08.001
  44. Gallo EF, 2016, LANCET PSYCHIAT, V3, P555, DOI 10.1016/S2215-0366(16)00096-1
  45. Goodwin A, 2016, TRIALS, V17, DOI 10.1186/s13063-016-1727-0
  46. Gould MS, 2009, AM J PSYCHIAT, V166, P992, DOI 10.1176/appi.ajp.2009.09040472
  47. Greenhill L, 2006, J AM ACAD CHILD PSY, V45, P1284, DOI 10.1097/01.chi.0000235077.32661.61
  48. Greenhill Laurence L, 2019, J Am Acad Child Adolesc Psychiatry, DOI 10.1016/j.jaac.2019.06.019
  49. Greydanus DE, 2009, NEUROPSYCH DIS TREAT, V5, P171
  50. Habel LA, 2011, JAMA-J AM MED ASSOC, V306, P2673, DOI 10.1001/jama.2011.1830
  51. Halperin JM, 2012, NEUROTHERAPEUTICS, V9, P531, DOI 10.1007/s13311-012-0123-z
  52. Harold GT, 2013, J CHILD PSYCHOL PSYC, V54, P1038, DOI 10.1111/jcpp.12100
  53. Hoogman M, 2017, LANCET PSYCHIAT, V4, P310, DOI 10.1016/S2215-0366(17)30049-4
  54. Ibrahim K, 2015, J ATTEN DISORD, V19, P551, DOI 10.1177/1087054714548035
  55. James Sarah-Naomi, 2016, Biol Psychiatry Cogn Neurosci Neuroimaging, V1, P539, DOI 10.1016/j.bpsc.2016.06.003
  56. Jensen PS, 1999, ARCH GEN PSYCHIAT, V56, P1073
  57. Johnson MH, 2015, J CHILD PSYCHOL PSYC, V56, P228, DOI 10.1111/jcpp.12328
  58. Kennedy M, 2016, J CHILD PSYCHOL PSYC, V57, P1113, DOI 10.1111/jcpp.12576
  59. KLEIN RG, 1988, ARCH GEN PSYCHIAT, V45, P1127
  60. Klingberg T, 2005, J AM ACAD CHILD PSY, V44, P177, DOI 10.1097/00004583-200502000-00010
  61. Knopik VS, 2005, PSYCHOL MED, V35, P625, DOI 10.1017/S0033291704004155
  62. Kofler MJ, 2016, CLIN PSYCHOL REV, V46, P12, DOI 10.1016/j.cpr.2016.04.004
  63. Konrad A, 2010, EUR J NEUROSCI, V31, P912, DOI 10.1111/j.1460-9568.2010.07110.x
  64. Kortekaas-Rijlaarsdam AF, 2019, EUR CHILD ADOLES PSY, V28, P155, DOI 10.1007/s00787-018-1106-3
  65. Krasner AJ, 2018, J ATTEN DISORD, V22, P827, DOI 10.1177/1087054715617532
  66. KRISANAPRAKORNK.T, 2010, COCHRANE DB SYST REV, V16, P6507
  67. Kuntsi J, 2004, AM J MED GENET B, V124B, P41, DOI 10.1002/ajmg.b.20076
  68. Lahey BB, 2005, ARCH GEN PSYCHIAT, V62, P896, DOI 10.1001/archpsyc.62.8.896
  69. Lee MJ, 2016, J AFFECT DISORDERS, V189, P110, DOI 10.1016/j.jad.2015.09.015
  70. Lichtenstein P, 2012, NEW ENGL J MED, V367, P2006, DOI 10.1056/NEJMoa1203241
  71. Lugo-Candelas C, 2018, LANCET PSYCHIAT, V5, P771, DOI 10.1016/S2215-0366(18)30356-0
  72. Martin J, 2015, TRANSL PSYCHIAT, V5, DOI 10.1038/tp.2015.5
  73. McCann D, 2007, LANCET, V370, P1560, DOI 10.1016/S0140-6736(07)61306-3
  74. McInerney RJ, 2003, CHILD NEUROPSYCHOL, V9, P91, DOI 10.1076/chin.9.2.91.14506
  75. Metin B, 2012, BIOL PSYCHIAT, V72, P990, DOI 10.1016/j.biopsych.2012.08.023
  76. Moffitt TE, 2015, AM J PSYCHIAT, V172, P967, DOI 10.1176/appi.ajp.2015.14101266
  77. Molina BSG, 2013, J AM ACAD CHILD PSY, V52, P250, DOI 10.1016/j.jaac.2012.12.014
  78. Molina BSG, 2009, J AM ACAD CHILD PSY, V48, P484, DOI [10.1097/CHI.0b013e31819c23d0, 10.1097/CHI.0b013e3181ba3e04]
  79. Mur M, 2007, J CLIN PSYCHIAT, V68, P1078, DOI 10.4088/JCP.v68n0715
  80. NICE, 2018, ATT DEF HYP DIS DIAG
  81. Nigg J, 2010, J AM ACAD CHILD PSY, V49, P863, DOI 10.1016/j.jaac.2010.01.025
  82. Nigg JT, 2008, BIOL PSYCHIAT, V63, P325, DOI 10.1016/j.biopsych.2007.07.013
  83. Nigg JT, 2007, J AM ACAD CHILD PSY, V46, P362, DOI 10.1097/01.chi.0000246054.76167.44
  84. Nigg JT, 2016, PSYCHOL SCI, V27, P257, DOI 10.1177/0956797615618365
  85. Nigg JT, 2005, BIOL PSYCHIAT, V57, P1224, DOI 10.1016/j.biopsych.2004.08.025
  86. Nomura Y, 2012, ARCH PEDIAT ADOL MED, V166, P337, DOI 10.1001/archpediatrics.2011.784
  87. O'Hearn K, 2008, DEV PSYCHOPATHOL, V20, P1103, DOI 10.1017/S0954579408000527
  88. Palacio Juan David, 2009, rev.colomb.psiquiatr., V38, P35
  89. Peleg-Raibstein D, 2016, TRANSL PSYCHIAT, V6, DOI 10.1038/tp.2016.176
  90. Peng XL, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0079476
  91. Plichta MM, 2014, NEUROSCI BIOBEHAV R, V38, P125, DOI 10.1016/j.neubiorev.2013.07.012
  92. Pliszka SR, 2006, J AM ACAD CHILD PSY, V45, P642, DOI 10.1097/01.chi.0000215326.51175.eb
  93. Pliszka S, 2007, J AM ACAD CHILD PSY, V46, P894, DOI 10.1097/chi.0b013e318054e724
  94. Polanczyk G, 2007, AM J PSYCHIAT, V164, P942, DOI 10.1176/appi.ajp.164.6.942
  95. Polanczyk GV, 2014, INT J EPIDEMIOL, V43, P434, DOI 10.1093/ije/dyt261
  96. Posner J, 2013, CLIN MANUAL CHILD AD
  97. Posner J, 2018, J AM ACAD CHILD PSY, V57, P813, DOI 10.1016/j.jaac.2018.07.874
  98. Posner J, 2014, NEUROPSYCHOL REV, V24, P3, DOI 10.1007/s11065-014-9251-z
  99. Posner J, 2013, PSYCHIAT RES-NEUROIM, V213, P24, DOI 10.1016/j.pscychresns.2013.01.004
  100. Potter AS, 2004, PSYCHOPHARMACOLOGY, V176, P182, DOI 10.1007/s00213-004-1874-y
  101. Rabiner DL, 2013, CURR PSYCHIAT REP, V15, DOI 10.1007/s11920-013-0375-2
  102. Reed GM, 2019, WORLD PSYCHIATRY, V18, P3, DOI 10.1002/wps.20611
  103. Rimestad ML, 2019, J ATTEN DISORD, V23, P423, DOI 10.1177/1087054716648775
  104. Rydell M, 2018, J CHILD PSYCHOL PSYC, V59, P863, DOI 10.1111/jcpp.12882
  105. Safer DJ, 2015, J ATTEN DISORD, V22, P107
  106. Sallee FR, 2009, J AM ACAD CHILD PSY, V48, P155, DOI 10.1097/CHI.0b013e318191769e
  107. Scahill L, 2001, AM J PSYCHIAT, V158, P1067, DOI 10.1176/appi.ajp.158.7.1067
  108. Schachter HA, 2001, CAN MED ASSOC J, V165, P1475
  109. Scheffler RM, 2007, HEALTH AFFAIR, V26, P450, DOI 10.1377/hlthaff.26.2.450
  110. Schwartz S, 2014, J AM ACAD CHILD PSY, V53, P174, DOI 10.1016/j.jaac.2013.11.005
  111. Sergeant J, 2000, NEUROSCI BIOBEHAV R, V24, P7, DOI 10.1016/S0149-7634(99)00060-3
  112. Shaw P, 2007, P NATL ACAD SCI USA, V104, P19649, DOI 10.1073/pnas.0707741104
  113. Shytle R Douglas, 2002, World J Biol Psychiatry, V3, P150, DOI 10.3109/15622970209150616
  114. Sibley MH, 2018, AM J PSYCHIAT, V175, P140, DOI 10.1176/appi.ajp.2017.17030298
  115. Simon V, 2009, BRIT J PSYCHIAT, V194, P204, DOI 10.1192/bjp.bp.107.048827
  116. Smith E, 2017, EUR CHILD ADOLES PSY, V26, P123, DOI 10.1007/s00787-016-0876-8
  117. Smoller JW, 2019, MOL PSYCHIATR, V24, P409, DOI 10.1038/s41380-017-0010-4
  118. Sonuga-Barke EJS, 2007, NEUROSCI BIOBEHAV R, V31, P977, DOI 10.1016/j.neubiorev.2007.02.005
  119. Sonuga-Barke EJS, 2010, J AM ACAD CHILD PSY, V49, P345, DOI 10.1016/j.jaac.2009.12.018
  120. Sonuga-Barke EJS, 2002, BEHAV BRAIN RES, V130, P29, DOI 10.1016/S0166-4328(01)00432-6
  121. Stevenson J, 2014, J CHILD PSYCHOL PSYC, V55, P416, DOI 10.1111/jcpp.12215
  122. Strauss M, 2018, PSYCHIAT RES, V261, P102, DOI 10.1016/j.psychres.2017.12.043
  123. Swanson JM, 2009, CURR PSYCHIAT REP, V11, P399, DOI 10.1007/s11920-009-0060-7
  124. Taylor FB, 2001, J CLIN PSYCHOPHARM, V21, P223, DOI 10.1097/00004714-200104000-00015
  125. Thapar A, 2018, AM J PSYCHIAT, V175, P943, DOI 10.1176/appi.ajp.2018.18040383
  126. Velligan D I, 1999, Semin Clin Neuropsychiatry, V4, P24
  127. Walton E, 2017, MOL PSYCHIATR, V22, P250, DOI 10.1038/mp.2016.85
  128. Wang Y, 2019, LANCET PSYCHIAT, V6, P667, DOI 10.1016/S2215-0366(19)30179-8
  129. Whitehouse PJ, 2004, PROG BRAIN RES, V145, P311, DOI 10.1016/S0079-6123(03)45022-X
  130. Wigal SB, 2013, J ATTEN DISORD, V17, P279, DOI 10.1177/1087054712454192
  131. Wilens TE, 2015, J AM ACAD CHILD PSY, V54, P916, DOI 10.1016/j.jaac.2015.08.016
  132. World Federation of ADHD, 2019, WORLD FED ADHD GUID
  133. World Health Organization, 2018, ICD 11 MORT MORB STA
  134. World Health Organization, 2018, INT STAT CLASS DIS R
  135. Wright N, 2015, J CHILD PSYCHOL PSYC, V56, P598, DOI 10.1111/jcpp.12398