ASSESSMENT OF THE USE OF TRANEXAMIC ACID AFTER TOTAL KNEE ARTHROPLASTY

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art_LEITE_ASSESSMENT_OF_THE_USE_OF_TRANEXAMIC_ACID_AFTER_2020.PDF (200.51 KB)
Citações na Scopus
6
Tipo de produção
article
Data de publicação
2020
DOI
SciELO
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ATHA COMUNICACAO & EDITORA
Autores
Citação
ACTA ORTOPEDICA BRASILEIRA, v.28, n.2, p.74-77, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective: To evaluate the profile of blood loss and blood transfusions after the introduction of Tranexamic acid (TXA) in a tertiary university hospital in Brazil. Methods: 173 patients were retrospectively divided into two groups: the ones who received TXA and the control group. Hemoglobin levels (Hb), drain output, transfusion rates, and thromboembolic events were measured. Results: Among the patients included in this study, 82 cases received TXA. Blood transfusion occurred in 3 cases of the TXA group (3.7%), and in 27 control group cases (29.7%; p < 0.001). The average Hb decrease was 2.7 g/dl (+/- 1.39) and the median drain output was 270 mL in the TXA group. In the control group, the values were 3.41 g/dl (+/- 1.34; p < 0.001) and 460 mL (p < 0.001), respectively. Thromboembolic events occurred in 2 TXA group cases (2.4%) and in 3 control group cases (3.3%; p > 0.999). Conclusion: TXA was effective in reducing blood transfusion rates, Hb decrease, and drain output on the 1st postoperative day without increasing thromboembolic events.
Palavras-chave
Tranexamic Acid, Blood Transfusion, Knee Replacement Arthroplasty
URI
https://observatorio.fm.usp.br/handle/OPI/36024
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MOT
Artigos e Materiais de Revistas Científicas - HC/IOT
Artigos e Materiais de Revistas Científicas - HU
Artigos e Materiais de Revistas Científicas - LIM/05
Artigos e Materiais de Revistas Científicas - LIM/41