LIM/05 - Laboratório de Poluição Atmosférica Experimental

O Laboratório de Poluição Atmosférica Experimental é ligado ao Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: patologia pulmonar; poluição atmosférica e seus efeitos sobre a saúde humana; toxicologia ambiental; fisiopatologia da lesão pulmonar aguda; mecânica pulmonar; imunopatologia e remodelamento da asma; patologia da doença pulmonar obstrutiva crônica; epidemiologia ambiental e educação ambiental; patologia pulmonar à autópsia.

Site oficial:http://limhc.fm.usp.br/portal/lim05-laboratorio-de-poluicao-atmosferica-experimental/

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Recent Submissions

  1. FINE INHALABLE PARTICULATE MATTER (PM<sub>2.5</sub>) PRESENT IN AIR POLLUTION AND ITS EFFECTS ON MALE GERM CELLS CHROMATIN PACKAGING.

    FERTILITY AND STERILITY, v.120, n.4, suppl.S, p.E213-E214, 2023

  2. Engaging stakeholders to level up COPD care in LMICs: lessons learned from the ""Breathe Well"" programme in Brazil, China, Georgia, and North Macedonia

    BMC HEALTH SERVICES RESEARCH, v.24, n.1, article ID 66, 10p, 2024

    BackgroundEffective stakeholder engagement in health research is increasingly being recognised and promoted as an important pathway to closing the gap between knowledge production and its use in health systems. However, little is known about its process and impacts, particularly in low-and middle...

  3. Changes after 12 years of follow-up severe asthma patients cohort: higher obstruction and comorbidities, but significant better quality of life

    JOURNAL OF ASTHMA, v.60, n.2, p.298-303, 2023

    Background The Brazilian Cohort of Asthma Sao Paulo (BRASASP) had a well-characterized severe asthmatic in Brazil, with 12 years of follow-up under standard treatment. Methods Sequential assessment of patients with uncontrolled asthma from BRASASP cohort was carried out with 12 years of follow-up...

  4. Ultrasonography on the non-living. Current approaches.

    MEDICAL ULTRASONOGRAPHY, v.25, n.1, p.56-65, 2023

    The vast majority of clinicians associate diagnostic ultrasound with a tool that is designed for the living patient. However, it is of course possible to apply this imaging technology to evaluate the recently deceased patient for postmortem diagnosis, or even just examine postmortem tissue. We de...

  5. COVID-19: detection methods in post-mortem samples

    PATHOLOGICA, v.115, n.5, p.263-274, 2023

    COVID-19 identification is routinely performed on fresh samples, such as nasopharyngeal and oropharyngeal swabs, even if, the detection of the virus in formalin-fixed paraffinembedded (FFPE) autopsy tissues could help to underlie mechanisms of the pathogenesis that are not well understood. The go...

  6. miRNA-143 expression is associated with inflammation and time of exposure to amniotic fluid in experimental gastroschisis

    CLINICS, v.78, article ID 100311, 7p, 2023

    Objective: Gastroschisis (GS) is a congenital anomaly in the abdominal wall with the intestinal loops exiting laterally to the umbilicus. The contact of the loops with Amniotic Fluid (AF) causes an inflammatory process in the exposed part, leading to an extended hospital stay and an increased ris...

  7. Mental health among children and adolescents after SARS-CoV-2 infection: A prospective study in a tertiary university hospital

    JOURNAL OF INFECTION, v.87, n.6, p.576-578, 2023

  8. A novel program of infiltrative control in astrocytomas: ADAM23 depletion promotes cell invasion by activating <bold>γ</bold>-secretase complex

    NEURO-ONCOLOGY ADVANCES, v.5, n.1, article ID vdad147, 13p, 2023

    Background. Infiltration is a life-threatening growth pattern in malignant astrocytomas and a significant cause of therapy resistance. It results in the tumor cell spreading deeply into the surrounding brain tissue, fostering tumor recurrence and making complete surgical resection impossible. We ...

  9. Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection

    VACCINES, v.11, n.11, article ID 1732, 17p, 2023

    Mucosal vaccination appears to be suitable to protect against SARS-CoV-2 infection. In this study, we tested an intranasal mucosal vaccine candidate for COVID-19 that consisted of a cationic liposome containing a trimeric SARS-CoV-2 spike protein and CpG-ODNs, a Toll-like receptor 9 agonist, as a...

  10. Association between illness perception and clinical control, quality of life, physical activity, and psychosocial status in subjects with moderate to severe asthma: a cluster analysis

    JOURNAL OF ASTHMA, v.60, n.1, p.115-122, 2023

    Background: Illness perception (IP) is a psychosocial factor involved in several chronic diseases and is associated with relevant clinical outcomes. However, the relationship between IP and health-related quality of life (HRQoL), psychosocial status, and physical activity in daily life (PADL) in ...