LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação

O Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação é ligado ao Departamento de Cardiopneumologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: estudo da reação inflamatória e da microcirculação nas disfunções circulatórias; alterações circulatórias e da resposta inflamatória no emprego da circulação artificial; métodos de prevenção e controle das alterações do enxerto após o transplante cardíaco; mecanismos de proteção medular na abordagem cirúrgica da aorta torácica; desenvolvimento biotecnológico e integração morfofuncional de substitutos valvares biológicos; mecanismos de hipertrofia e métodos de preparo das câmaras ventriculares.

Site oficial: http://limhc.fm.usp.br/portal/lim11-laboratorio-de-cirurgia-cardiovascular-e-fisiopatologia-da-circulacao/

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Recent Submissions

  1. Data-driven, cross-disciplinary collaboration: lessons learned at the largest academic health center in Latin America during the COVID-19 pandemic

    FRONTIERS IN PUBLIC HEALTH, v.12, article ID 1369129, 15p, 2024

    Introduction The COVID-19 pandemic has prompted global research efforts to reduce infection impact, highlighting the potential of cross-disciplinary collaboration to enhance research quality and efficiency.Methods At the FMUSP-HC academic health system, we implemented innovative flow management r...

  2. Delayed left main coronary obstruction following transfemoral inovare transcatheter aortic valve replacement: A challenging case

    JOURNAL OF CARDIOLOGY CASES, v.25, n.2, p.61-64, 2022

    Coronary obstruction is an uncommon and severe complication after a transcatheter aortic valve replacement (TAVR), that occurs during the procedure in the vast majority of patients. In the present case even in the absence of classic risk factors, an acute coronary syndrome occurred one day after ...

  3. Rare association between giant-cell aortitis and giant-cell aortic valvulitis

    AUTOPSY AND CASE REPORTS, v.13, article ID e2023449, p, 2023

    Giant cell arteritis (GCA) is a type of chronic vasculitis that affects medium and large-caliber arteries, frequently related to aortic involvement and, consequently, to aneurysm formation. However, associated valvulitis with giant cells is uncommon. We describe the case of a 50-year-old female p...

  4. Reduced-dose prasugrel monotherapy without aspirin after PCI with the SYNERGY stent in East Asian patients presenting with chronic coronary syndromes or non-ST-elevation acute coronary syndromes: rationale and design of the ASET Japan pilot study

    ASIAINTERVENTION, v.9, n.1, p.39-48, 2023

    The Acetyl Salicylic Elimination Trial (ASET) Japan pilot study is a multicentre, single-arm, open-label, proof-of-concept study with a stopping rule based on the occurrence of definite stent thrombosis. This study aims to demonstrate the feasibility and safety of low-dose prasugrel monotherapy f...

  5. Rivaroxaban versus warfarin in postoperative atrial fibrillation: Cost-effectiveness analysis in a single-center, randomized, and prospective trial

    JTCVS OPEN, v.15, p.199-210, 2023

    Objectives: Postoperative atrial fibrillation is the most common clinical complication after coronary artery bypass graft surgery. It is associated with a high risk of both stroke and death and increases the length of hospital stay and costs. This study aimed to evaluate anticoagulants in postope...

  6. Degenerative or rheumatic: after all, what is the most prevalent etiology of mitral regurgitation in developing countries?

    EUROPEAN HEART JOURNAL, v.44, suppl.2, 2023

  7. USING MACHINE LEARNING TO ASSESS POTENTIAL CASES OF TRANSTHYRETIN CARDIAC AMYLOIDOSIS IN BRAZIL: A RETROSPECTIVE DATABASE APPROACH

    VALUE IN HEALTH, v.26, n.12, suppl.S, p.S415-S415, 2023

  8. PRIMARY RESULTS FROM APOLLO-B, A PHASE 3 STUDY OF PATISIRAN IN PATIENTS WITH TRANSTHYRETIN-MEDIATED AMYLOIDOSIS WITH CARDIOMYOPATHY

    EUROPEAN HEART JOURNAL SUPPLEMENTS, v.25, suppl.D, p.D28-D28, 2023

  9. Non-invasive assessment of myocardial stiffness by the two-dimensional shear wave elastography ultrasound technique in patients with amyloidosis and Fabry disease

    EUROPEAN HEART JOURNAL, v.44, suppl.2, 2023

  10. MACHINE LEARNING PREDICTION MODELS OF CORONARY PLAQUE PROGRESSION AFTER ONE-YEAR OF HIGH-INTENSITY ROSUVASTATIN THERAPY FROM INTRAVASCULAR ULTRASOUND IMAGES

    ATHEROSCLEROSIS, v.379, suppl.1, p.S166-S167, 2023