LIM/27 - Laboratório de Neurociências
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Disturbed Oligodendroglial Maturation Causes Cognitive Dysfunction in Schizophrenia: A New Hypothesis
SCHIZOPHRENIA BULLETIN, v.49, n.6, p.1614-1624, 2023
Background and Hypothesis Cognitive impairment is a hallmark of schizophrenia, but no effective treatment is available to date. The underlying pathophysiology includes disconnectivity between hippocampal and prefrontal brain regions. Supporting evidence comes from diffusion-weighted imaging studi...
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New treatment strategies for mental health
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, v.273, n.7, p.1399-1401, 2023
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Cellular pathology in the limbic system in schizophrenia
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, v.273, n.6, p.1207-1208, 2023
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Data-driven, cross-disciplinary collaboration: lessons learned at the largest academic health center in Latin America during the COVID-19 pandemic
FRONTIERS IN PUBLIC HEALTH, v.12, article ID 1369129, 15p, 2024
Introduction The COVID-19 pandemic has prompted global research efforts to reduce infection impact, highlighting the potential of cross-disciplinary collaboration to enhance research quality and efficiency.Methods At the FMUSP-HC academic health system, we implemented innovative flow management r...
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Employment, education, and clinical characteristics in older-age bipolar disorder: Analysis from the GAGE-BD database project
BIPOLAR DISORDERS, v.25, suppl.1, Special Issue, p.93-93, 2023
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Effects of Exercise on Structural and Functional Brain Patterns in Schizophrenia-Data From a Multicenter Randomized-Controlled Study
SCHIZOPHRENIA BULLETIN, v.50, n.1, p.145-156, 2024
Background and Hypothesis: Aerobic exercise interventions in people with schizophrenia have been demonstrated to improve clinical outcomes, but findings regarding the underlying neural mechanisms are limited and mainly focus on the hippocampal formation. Therefore, we conducted a global explorato...
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Publishing Negative Results of Neurobiological Studies in Mental Disorders Will Advance Knowledge in Pathophysiology
SCHIZOPHRENIA BULLETIN, v.49, n.3, p.539-541, 2023
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Exercise as an add-on treatment in individuals with schizophrenia: Results from a large multicenter randomized controlled trial
PSYCHIATRY RESEARCH, v.328, article ID 115480, 11p, 2023
Current treatment methods do not achieve recovery for most individuals with schizophrenia, and symptoms such as negative symptoms and cognitive deficits often persist. Aerobic endurance training has been suggested as a potential add-on treatment targeting both physical and mental health. We perfo...
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Treatment of negative symptoms in schizophrenia: a challenge for clinical research
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, v.273, n.3, p.525-526, 2023
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The relationship between internet gaming disorder and psychotic experiences: cyberbullying and insomnia severity as mediators
BMC PSYCHIATRY, v.23, n.1, article ID 857, 14p, 2023
BackgroundThe nature of the relationship between Internet Gaming Disorder (IGD) and psychosis is unclear so far. There is evidence that greater time spent in playing video games may expose players to both insomnia and a toxic online environment with widespread cyberbullying. These two possible co...
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