LIM/28 - Laboratório de Cirurgia de Cabeça e Pescoço

O Laboratório de Cirurgia de Cabeça e Pescoço é ligado ao Departamento de Cirurgia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: prevenção e diagnóstico precoce do câncer bucal; prevenção primária do câncer oral; tratamento do câncer da cavidade oral; tratamento oncológico do câncer de cabeça e pescoço; cirurgia endovascular; aneurisma da aorta; projeto genoma; carcinogênese do câncer de cabeça e pescoço e imunoterapia do câncer de cabeça e pescoço.

Site oficial: http://limhc.fm.usp.br/portal/lim28-laboratorio-de-cirurgia-vascular-e-da-cabeca-e-pescoco/

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Recent Submissions

  1. microRNAs associated with metastatic potential in salivary gland mucoepidermoid carcinoma

    CANCER RESEARCH, v.83, n.7, suppl.S, 2023

  2. Medical students' and residents' views on euthanasia

    BMC MEDICAL ETHICS, v.24, n.1, article ID 109, 9p, 2023

    BackgroundDoctors are increasingly faced with end-of-life decisions. Little is known about how medical students approach euthanasia. The objective of this study was to evaluate, among medical students and residents, the view on euthanasia and its variants; correlate such a view with empathy and r...

  3. Sialendoscopy for treatment of major salivary glands diseases: a comprehensive analysis of published systematic reviews and meta-analyses

    BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, v.89, n.5, article ID 101293, 13p, 2023

    Objectives: Sialendoscopy is a minimally invasive procedure used to diagnose and treat obstructive salivary gland diseases. Previous studies in the topic have shown mixed results. The present study aimed to evaluate the efficacy and safety of sialendoscopy through previous systematic reviews for ...

  4. Oral squamous cell carcinoma cancer stem cells have different drug sensitive to pharmacological NFκB and histone deacetylation inhibition

    AMERICAN JOURNAL OF CANCER RESEARCH, v.13, n.12, p.6038-6050, 2023

    Despite many progresses in the development of new systemic therapies for oral squamous cell carcinoma (OSCC), the five-year survival rate of OSCC is low. The traditional chemotherapies approach (cisplatin - CDDP) shows some limitations like drug toxicity, limited efficacy, and drug resistance. Pr...

  5. Cryoablation of Benign Thyroid Nodules: Preliminary Experience in 3 Cases

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, v.34, n.12, p.2259-2263, 2023

  6. Management of Older Patients with Head and Neck Cancer: A Comprehensive Review

    ADVANCES IN THERAPY, v.40, n.5, p.1957-1974, 2023

    The projected increase in life expectancy over the next few decades is expected to result in a rise in age-related diseases, including cancer. Head and neck cancer (HNC) is a worldwide health problem with high rates of morbidity and mortality. In this report, we have critically reviewed the liter...

  7. The use of deep learning state-of-the-art architectures for oral epithelial dysplasia grading: A comparative appraisal

    JOURNAL OF ORAL PATHOLOGY & MEDICINE, v.52, n.10, p.980-987, 2023

    Background: Dysplasia grading systems for oral epithelial dysplasia are a source of disagreement among pathologists. Therefore, machine learning approaches are being developed to mitigate this issue.Methods: This cross-sectional study included a cohort of 82 patients with oral potentially maligna...

  8. DNA methylation-based depiction of the immune microenvironment and immune-associated long non-coding RNAs in oral cavity squamous cell carcinomas

    BIOMEDICINE & PHARMACOTHERAPY, v.167, article ID 115559, 14p, 2023

    Oral cavity squamous cell carcinoma (OSCC) is a complex and dynamic disease characterized by clinicopathological and molecular heterogeneity. Spatial and temporal heterogeneity of cell subpopulations has been associated with cancer progression and implicated in the prognosis and therapy response....

  9. Overview of glottic laryngeal cancer treatment recommendation changes in the NCCN guidelines from 2011 to 2022

    CANCER REPORTS, v.6, n.8, 2023

    BackgroundThe treatment of glottic cancer remains challenging, especially with regard to morbidity reduction and larynx preservation rates. The National Comprehensive Cancer Network (NCCN) has published guidelines to aid decision-making about this treatment according to the tumor site, clinical s...

  10. Hematopoietic colony-stimulating factors in head and neck cancers: Recent advances and therapeutic challenges

    CYTOKINE, v.173, article ID 156417, 17p, 2024

    Colony-stimulating factors (CSFs) are key cytokines responsible for the production, maturation, and mobilization of the granulocytic and macrophage lineages from the bone marrow, which have been gaining attention for playing pro-and/or anti-tumorigenic roles in cancer. Head and neck cancers (HNCs...