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1. WT1 Pathogenic Variants are Associated with a Broad Spectrum of Differences in Sex Development Phenotypes and Heterogeneous Progression of Renal Disease

   SEXUAL DEVELOPMENT, v.16, n.1, p.46-54, 2022

   Wilms' tumor suppressor gene 1 (WT1) plays an essential role in urogenital and kidney development. Heterozygous germline pathogenic allelic variants of WT1 have been classically associated with Denys-Drash syndrome (DDS) and Frasier syndrome (FS). Usually, exonic pathogenic missense variants in t...

2. Mitochondrial Calcium Dynamics and Bioenergetics in Autosomal Dominant Polycystic Kidney Disease: more pieces to the puzzle

   FREE RADICAL BIOLOGY AND MEDICINE, v.208, suppl.1, p.S62-S62, 2023

3. ANCA-associated glomerulonephritis and lupus nephritis following COVID-19 vaccination: a case report and literature review

   FRONTIERS IN IMMUNOLOGY, v.14, article ID 1298622, 7p, 2024

   With the coverage of COVID-19 vaccination, it has been possible to observe the potential side effects of SARS-CoV-2 vaccines, with the most common ones being fever, myalgia, headache, and fatigue. However, an association has been observed between new and recurrent kidney injuries, mainly glomerul...

4. Effects of early exercise on cardiac function and lipid metabolism pathway in heart failure

   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, v.27, n.19, p.2956-2969, 2023

   We employed an early training exercise program, immediately after recovery from surgery, and before severe cardiac hypertrophy, to study the underlying mechanism involved with the amelioration of cardiac dysfunction in aortic stenosis (AS) rats. As ET induces angiogenesis and oxygen support, we a...

5. The influence of dapagliflozin on cardiac remodeling, myocardial function and metabolomics in type 1 diabetes mellitus rats

   DIABETOLOGY & METABOLIC SYNDROME, v.15, n.1, article ID 223, 13p, 2023

   BackgroundSodium-glucose cotransporter (SGLT)2 inhibitors have displayed beneficial effects on the cardiovascular system in diabetes mellitus (DM) patients. As most clinical trials were performed in Type 2 DM, their effects in Type 1 DM have not been established.ObjectiveTo evaluate the influence...

6. Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial

   LANCET, v.402, n.10417, p.2077-2090, 2023

   Background Sparsentan, a novel, non-immunosuppressive, single-molecule, dual endothelin angiotensin receptor antagonist, significantly reduced proteinuria versus irbesartan, an angiotensin II receptor blocker, at 36 weeks (primary endpoint) in patients with immunoglobulin A nephropathy in the pha...

7. Integrated control strategies for dengue, Zika, and Chikungunya virus infections

   FRONTIERS IN IMMUNOLOGY, v.14, article ID 1281667, 13p, 2023

   Arboviruses are a major threat to public health in tropical regions, encompassing over 534 distinct species, with 134 capable of causing diseases in humans. These viruses are transmitted through arthropod vectors that cause symptoms such as fever, headache, joint pains, and rash, in addition to m...

8. Neuroimmunology of rabies: New insights into an ancient disease

   JOURNAL OF MEDICAL VIROLOGY, v.95, n.10, article ID e29042, 17p, 2023

   Rabies is an ancient neuroinvasive viral (genus Lyssavirus, family Rhabdoviridae) disease affecting approximately 59,000 people worldwide. The central nervous system (CNS) is targeted, and rabies has a case fatality rate of almost 100% in humans and animals. Rabies is entirely preventable through...

9. A short-term high-sugar diet is an aggravating factor in experimental allergic contact dermatitis

   HELIYON, v.9, n.11, article ID e21225, 10p, 2023

   Allergic contact dermatitis (ACD) is an inflammatory skin reaction whose incidence has increased and has been associated with a dietary pattern rich in saturated fats and refined sugars. Considering the increased incidence of ACD and the lack of research about the influence of a short-term high-s...

10. Changes in Skeletal Muscle Protein Metabolism Signaling Induced by Glutamine Supplementation and Exercise

    NUTRIENTS, v.15, n.22, article ID 4711, 15p, 2023

    Aim: To evaluate the effects of resistance exercise training (RET) and/or glutamine supplementation (GS) on signaling protein synthesis in adult rat skeletal muscles. Methods: The following groups were studied: (1) control, no exercise (C); (2) exercise, hypertrophy resistance exercise training p...