LIM/32 - Laboratório de Otorrinolaringologia

O Laboratório de Otorrinolaringologia é ligado ao Departamento de Oftalmologia e otorrinolaringologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: pesquisa experimental e análise crítica das técnicas cirúrgicas sobre osso temporal; pesquisa em próteses eletrônicas cirurgicamente implantáveis para deficiência auditiva profunda; bases clínicas e experimentais da fisiopatologia e tratamento do zumbido e da hiperacusia; mecanismos fisiopatológicos dos distúrbios vestibulares periféricos; pesquisa anatômica e experimental das propriedades biomecânicas da laringe no desempenho das funções respiratória, fonatória e esfinctérica; distúrbios do anel linfático de Waldeyer e sua influência no desenvolvimento craniofacial e no sistema estomagotognático; correlação de fatores estruturais e microbiológicos na fisiopatogenia das rinossinusites; estudo da patogênese de nasoangiofibroma juvenil; alterações funcionais na mucosa nasal exposta a poluentes ambientais alérgenos.

Site oficial: http://limhc.fm.usp.br/portal/lim32-laboratorio-de-otorrinolaringologia/

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Recent Submissions

  1. “Benefits of the pedicled osteoplastic flap as a surgical approach of mastoidectomy in cochlear implant surgery”

    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, v.279, n.5, p.2259-2268, 2022

    Objective: To evaluate the esthetic and functional results of an osteoplastic flap for mastoid cavity closure in cochlear implant surgery. Study design: Double-blind, prospective, randomized clinical trial. Setting: tertiary referral center. Intervention(s): On hundred and twenty-six patients wer...

  2. Impact of Chronic Rhinosinusitis with Nasal Polyposis on IL-12 and IL-8

    IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, v.35, n.1, p.21-27, 2023

    Introduction: The pathophysiology of Chronic Rhinosinusitis is coordinated by distinct inflammatory reactions in different individuals. Inflammatory environments with a predominance of Th2 lymphocytes tend also to be rich in eosinophils. These environments are common during the formation of nasal...

  3. EVALUATION OF THE IMPACT OF EXPOSURE TO HEAT AND TO BY-PRODUCTS OF COMBUSTION ON THE HEALTH OF FIREFIGHTERS

    ANNALS OF BURNS AND FIRE DISASTERS, v.36, n.2, p.100-110, 2023

    Firefighters are often exposed to high temperatures and by-products of combustion, which can affect their health. In this study, we assessed the impact of acute exposure of firefighters in fire simulators. Twenty male firefighters were exposed to fire simulators, and observed in four phases: pre-...

  4. Individualized Vibrotactile Neurofeedback Training in Patients with Chronic Bilateral Vestibulopathy

    BRAIN SCIENCES, v.13, n.8, article ID 1219, 10p, 2023

    Patients with bilateral vestibulopathy (BVP) suffer from postural imbalance during daily life conditions, which in turn leads to a high frequency of falls. Unfortunately, vestibular rehabilitation has only modest and somewhat inconsistent effects in this patient group. Approximately 50% of BVP pa...

  5. Olfaction in nasal polyp patients after Reboot surgery: an endotype-based prospective study

    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, v.280, n.6, p.2821-2830, 2023

    Purpose To report biomarkers present in the olfactory mucosa in chronic rhinosinusitis with nasal polyps (CRSwNP) in comparison with nasal polyps and to nasal mucosal tissues from control patients. To evaluate the kinetics of smell over 6 months in patients who underwent Reboot surgery. Methods C...

  6. Predicting emotion perception abilities for cochlear implant users

    INTERNATIONAL JOURNAL OF AUDIOLOGY, v.62, n.10, p.946-954, 2023

    Objective In daily life, failure to perceive emotional expressions can result in maladjusted behaviour. For cochlear implant users, perceiving emotional cues in sounds remains challenging, and the factors explaining the variability in patients' sensitivity to emotions are currently poorly underst...

  7. White noise effect on listening effort among patients with chronic tinnitus and normal hearing thresholds

    BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, v.90, n.1, article ID 101340, 7p, 2024

    Objective: This study investigated the effects of WN on LE in subjects with chronic tinnitus and normal hearing thresholds. The study was a prospective, non-randomized, before-and-after, intra-participant intervention. Methods: Twenty-five subjects performed the following tests: conventional and ...

  8. Perivascular Innervation in the Nasal Mucosa and Clinical Findings in Patients with Allergic Rhinitis and Idiopathic Rhinitis

    INTERNATIONAL ARCHIVES OF OTORHINOLARYNGOLOGY, v.27, n.4, p.723-732, 2023

    Introduction The nonspecific hyperreactivity of rhinitis has been attributed to neurotrophins activating sensory nerves and inflammatory cells. The relationship between these markers and the intensity of the symptoms is not well established and few studies have evaluated individuals with idiopath...

  9. Communicative and Hearing Performance in Individuals with Cochlear Implants and Delayed Neuropsychomotor Development: A Longitudinal Analysis

    INTERNATIONAL ARCHIVES OF OTORHINOLARYNGOLOGY, v.27, n.3, p.487-498, 2023

    Introduction Between 15% to 30% of individuals with bilateral prelingual sensorineural hearing loss present with associated disabilities. Cochlear implant (CI) is an alternative treatment that provides consistent access to environmental and speech sounds, which results in significant benefits reg...

  10. Brazilian Society of Otology task force -- Vestibular Schwannoma -- evaluation and treatment

    BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, v.89, n.6, article ID 101313, 39p, 2023

    Objective: To review the literature on the diagnosis and treatment of vestibular schwannoma. Methods: Task force members were educated on knowledge synthesis methods, including electronic database search, review and selection of relevant citations, and critical appraisal of selected studies. Arti...