Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis

Imagem de Miniatura
Arquivos
art_BIO_Neuropsychological_testing_of_cognitive_impairment_in_euthymic_bipolar_2013.PDF (314.15 KB)
Citações na Scopus
471
Tipo de produção
article
Data de publicação
2013
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY-BLACKWELL
Autores
BOURNE, C.
AYDEMIR, O.
BALANZA-MARTINEZ, V.
BORA, E.
BRISSOS, S.
CAVANAGH, J. T. O.
CLARK, L.
CUBUKCUOGLU, Z.
DIAS, V. V.
DITTMANN, S.
Citação
ACTA PSYCHIATRICA SCANDINAVICA, v.128, n.3, p.149-162, 2013
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective: An association between bipolar disorder and cognitive impairment has repeatedly been described, even for euthymic patients. Findings are inconsistent both across primary studies and previous meta-analyses. This study reanalysed 31 primary data sets as a single large sample (N = 2876) to provide a more definitive view. Method: Individual patient and control data were obtained from original authors for 11 measures from four common neuropsychological tests: California or Rey Verbal Learning Task (VLT), Trail Making Test (TMT), Digit Span and/or Wisconsin Card Sorting Task. Results: Impairments were found for all 11 test-measures in the bipolar group after controlling for age, IQ and gender (Ps <= 0.001, E.S. = 0.26-0.63). Residual mood symptoms confound this result but cannot account for the effect sizes found. Impairments also seem unrelated to drug treatment. Some test-measures were weakly correlated with illness severity measures suggesting that some impairments may track illness progression. Conclusion: This reanalysis supports VLT, Digit Span and TMT as robust measures of cognitive impairments in bipolar disorder patients. The heterogeneity of some test results explains previous differences in meta-analyses. Better controlling for confounds suggests deficits may be smaller than previously reported but should be tracked longitudinally across illness progression and treatment.
Palavras-chave
bipolar disorder, cognitive impairment, review, neuropsychological tests
URI
https://observatorio.fm.usp.br/handle/OPI/4301
Referências
  1. ALTMAN EG, 1994, BIOL PSYCHIAT, V36, P124, DOI 10.1016/0006-3223(94)91193-2
  2. Andreazza AC, 2008, J AFFECT DISORDERS, V111, P135, DOI 10.1016/j.jad.2008.04.013
  3. Arts B, 2008, PSYCHOL MED, V38, P771, DOI 10.1017/S0033291707001675
  4. Balanza-Martinez V, 2005, PSYCHOTHER PSYCHOSOM, V74, P113, DOI 10.1159/000083170
  5. Bearden CE, 2001, BIPOLAR DISORD, V3, P106, DOI 10.1034/j.1399-5618.2001.030302.x
  6. Bech P, 1975, ACTA PSYCHIAT SCAND, V59, P1
  7. Mahon PB, 2011, AM J MED GENET B, V156B, P370, DOI 10.1002/ajmg.b.31172
  8. Bora E, 2009, J AFFECT DISORDERS, V113, P1, DOI 10.1016/j.jad.2008.06.009
  9. Bora E, 2007, BIPOLAR DISORD, V9, P468, DOI 10.1111/j.1399-5618.2007.00469.x
  10. Cavanagh JTO, 2002, BRIT J PSYCHIAT, V180, P320, DOI 10.1192/bjp.180.4.320
  11. Clark L, 2002, BRIT J PSYCHIAT, V180, P313, DOI 10.1192/bjp.180.4.313
  12. Clarke MJ, 2005, BEST PRACT RES CL OB, V19, P47, DOI 10.1016/j.bpobgyn.2004.10.011
  13. Cohen J., 1988, STAT POWER ANAL BEHA
  14. Cubukcuoglu Z, 2011, THESIS
  15. Delis D. C., 1987, CALIFORNIA VERBAL LE
  16. Dias VV, 2009, BIPOLAR DISORD, V11, P663, DOI 10.1111/j.1399-5618.2009.00733.x
  17. Dittmann S, 2007, BIPOLAR DISORD, V9, P63, DOI 10.1111/j.1399-5618.2007.00412.x
  18. Donaldson S, 2003, J CLIN PSYCHIAT, V64, P86
  19. El-Badri SM, 2001, BIPOLAR DISORD, V3, P79, DOI 10.1034/j.1399-5618.2001.030206.x
  20. Fleck DE, 2003, BIPOLAR DISORD, V5, P375, DOI 10.1034/j.1399-5618.2003.00055.x
  21. Fleck DE, 2008, BIPOLAR DISORD, V10, P539, DOI 10.1111/j.1399-5618.2008.00582.x
  22. Frangou S, 2005, BIOL PSYCHIAT, V58, P859, DOI 10.1016/j.biopsych.2005.04.056
  23. Glahn DC, 2006, BIPOLAR DISORD, V8, P117, DOI 10.1111/j.1399-5618.2006.00296.x
  24. Glahn DC, 2007, BIOL PSYCHIAT, V62, P910, DOI 10.1016/j.biopsych.2007.02.001
  25. Glahn DC, 2003, BIOL PSYCHIAT, V53, P624, DOI 10.1016/S0006-3223(02)01641-4
  26. Goodwin GM, 2008, EUR NEUROPSYCHOPHARM, V18, P535, DOI 10.1016/j.euroneuro.2008.03.003
  27. Goswami U, 2009, ACTA PSYCHIAT SCAND, V120, P456, DOI 10.1111/j.1600-0447.2009.01390.x
  28. Goswami U, 2006, BRIT J PSYCHIAT, V188, P366, DOI 10.1192/bjp.188.4.366
  29. Hamilton M, 1960, J NEUROL NEUROSUR PS, V23, P55
  30. Heaton R. K., 1981, WISCONSIN CARD SORTI
  31. Hellvin T, 2012, BIPOLAR DISORD, V14, P227, DOI 10.1111/j.1399-5618.2012.01004.x
  32. Higgins JPT, 2002, STAT MED, V21, P1539, DOI 10.1002/sim.1186
  33. Ioannidis JPA, 2005, PLOS MED, V2, P696, DOI 10.1371/journal.pmed.0020124
  34. Jamrozinski K, 2009, ACTA PSYCHIAT SCAND, V119, P365, DOI 10.1111/j.1600-0447.2008.01320.x
  35. Kaya E, 2007, PROG NEURO-PSYCHOPH, V31, P1387, DOI 10.1016/j.pnpbp.2007.06.003
  36. Kempton MJ, 2008, ARCH GEN PSYCHIAT, V65, P1017, DOI 10.1001/archpsyc.65.9.1017
  37. Kieseppa T, 2005, PSYCHOL MED, V35, P205, DOI 10.1017/S0033291704003125
  38. Krabbendam L, 2005, SCHIZOPHR RES, V80, P137, DOI 10.1016/j.schres.2005.08.004
  39. Kurtz MM, 2009, NEUROPSYCHOLOGY, V23, P551, DOI 10.1037/a0016277
  40. Mann-Wrobel MC, 2011, BIPOLAR DISORD, V13, P334, DOI 10.1111/j.1399-5618.2011.00935.x
  41. Martinez-Aran A, 2004, AM J PSYCHIAT, V161, P262, DOI 10.1176/appi.ajp.161.2.262
  42. Martinez-Aran A, 2007, BIPOLAR DISORD, V9, P103, DOI 10.1111/j.1399-5618.2007.00327.x
  43. Mohamed S, 1999, ARCH GEN PSYCHIAT, V56, P749, DOI 10.1001/archpsyc.56.8.749
  44. Moher D, 2009, J CLIN EPIDEMIOL, V62, P1006, DOI 10.1016/j.jclinepi.2009.06.005
  45. MONTGOMERY SA, 1979, BRIT J PSYCHIAT, V134, P382, DOI 10.1192/bjp.134.4.382
  46. Mora E, 2013, PSYCHOL MED, V43, P1187, DOI 10.1017/S0033291712001948
  47. Mur M, 2007, J CLIN PSYCHIAT, V68, P1078
  48. Nelson HE, 1991, NATL ADULT READING T
  49. Nuechterlein KH, 2008, AM J PSYCHIAT, V165, P203, DOI 10.1176/appi.ajp.2007.07010042
  50. Torrent Carla, 2012, J Clin Psychiatry, V73, pe899, DOI 10.4088/JCP.11m07471
  51. Quraishi S, 2002, J AFFECT DISORDERS, V72, P209, DOI 10.1016/S0165-0327(02)00091-5
  52. REITAN R. M., 1958, PERCEPT MOT SKILLS, V8, P271
  53. Rey A., 1964, EXAMEN CLIN PSYCHOL
  54. Rivas MA, 2011, NAT GENET, V43, P1066, DOI 10.1038/ng.952
  55. Robinson LJ, 2006, BIPOLAR DISORD, V8, P103, DOI 10.1111/j.1399-5618.2006.00277.x
  56. Robinson LJ, 2006, J AFFECT DISORDERS, V93, P105, DOI 10.1016/j.jad.2006.02.016
  57. Rush AJ, 2006, INT J METH PSYCH RES, V9, P45, DOI 10.1002/MPR.79
  58. Savitz J, 2005, BIPOLAR DISORD, V7, P216, DOI 10.1111/j.1399-5618.2005.00203.x
  59. Senturk V, 2007, BIPOLAR DISORD, V9, P136, DOI 10.1111/j.1399-5618.2007.00481.x
  60. Shao L, 2005, BIOL PSYCHIAT, V58, P879, DOI 10.1016/j.biopsych.2005.04-052
  61. Simonsen C, 2011, SCHIZOPHRENIA BULL, V37, P73, DOI 10.1093/schbul/sbp034
  62. Simonsen C, 2008, BIPOLAR DISORD, V10, P245, DOI 10.1111/j.1399-5618.2007.00492.x
  63. Smith DJ, 2006, BIPOLAR DISORD, V8, P40, DOI 10.1111/j.1399-5618.2006.00275.x
  64. Stoddart SDR, 2007, PSYCHOL MED, V37, P1613, DOI 10.1017/S0033291707000712
  65. Szoke A, 2006, PSYCHIAT RES, V144, P131, DOI 10.1016/j.psychres.2005.11.013
  66. Tan H, 2012, INT J NEUROPSYCHOPH, V15, P1275, DOI 10.1017/S1461145711001416
  67. Cichon S, 2009, MOL PSYCHIATR, V14, P10, DOI 10.1038/mp.2008.126
  68. Thompson JM, 2005, BRIT J PSYCHIAT, V186, P32, DOI 10.1192/bjp.186.1.32
  69. Torrent C, 2011, COMPR PSYCHIAT, V52, P203
  70. Torrent C, 2006, BRIT J PSYCHIAT, V189, P254, DOI 10.1192/bjp.bp.105.017269
  71. Torres IJ, 2007, ACTA PSYCHIAT SCAND, V116, P17, DOI 10.1111/j.1600-0447.2007.01055.x
  72. Vederine FE, 2011, PROG NEURO-PSYCHOPH, V35, P1820, DOI 10.1016/j.pnpbp.2011.05.009
  73. Wechsler D, 1987, WECHSLER MEMORY SCAL
  74. Wechsler D, 1999, WECHSLER ABBREVIATED
  75. Wechsler D., 1981, WECHSLER ADULT INTEL
  76. Yatham LN, 2010, BIPOLAR DISORD, V12, P351, DOI 10.1111/j.1399-5618.2010.00830.x
  77. YOUNG RC, 1978, BRIT J PSYCHIAT, V133, P429, DOI 10.1192/bjp.133.5.429
  78. Zalla T, 2004, PSYCHIAT RES, V121, P207, DOI 10.1016/S0165-1781(03)00252-X

Coleções
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/23