<p>Nonoperative Management of Rectal Cancer The Watch and Wait Strategy</p>

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art_VAILATI_pNonoperative_Management_of_Rectal_Cancer_The_Watch_and_2022.PDF (684.52 KB)
Citações na Scopus
8
Tipo de produção
article
Data de publicação
2022
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
W B SAUNDERS CO-ELSEVIER INC
Autores
VAILATI, Bruna Borba
JULIAO, Guilherme Pagin Sao
PEREZ, Rodrigo Oliva
Citação
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, v.31, n.2, Special Issue, p.171-182, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Over the past few decades, rectal cancer management has become increasingly challenging for multiple reasons. Proper imaging using dedicated magnetic resonance (MR), standardization of total mesorectal excision (TME), and incorporation of neoadjuvant treatment regimens have contributed to a significant decrease in local recurrence rates while minimizing the need for definitive stomas (therefore allowing for sphincter-preservation alternatives).1 & ndash;3 However, the observation of complete tumor response to radiation (RT) or chemoradiation (CRT) led to the proposal of organpreservation strategies with avoidance of immediate surgery and close surveillance (Watch and Wait strategy) in selected patients.4 Initially considered for a very restricted subgroup of patients, the use of more contemporary neoadjuvant treatment regimens has resulted in a higher proportion of patients achieving complete tumor regression.5 The purpose of the present article is to review the current evidence related to the selection criteria and outcomes in patients enrolled in this Watch and Wait strategy. <comment>Superscript/Subscript Available</comment
Palavras-chave
Watch & wait, Organ preservation, Rectal cancer, Neoadjuvant therapy, Clinical complete response
URI
https://observatorio.fm.usp.br/handle/OPI/47115
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MGT
Artigos e Materiais de Revistas Científicas - ODS/03