Reduced Diffusion in Neurocysticercosis: Circumstances of Appearance and Possible Natural History Implications
Carregando...
Citações na Scopus
21
Tipo de produção
article
Data de publicação
2013
Título da Revista
ISSN da Revista
Título do Volume
Editora
AMER SOC NEURORADIOLOGY
Autores
Citação
AMERICAN JOURNAL OF NEURORADIOLOGY, v.34, n.2, p.310-316, 2013
Resumo
BACKGROUND AND PURPOSE: Few studies discuss DWI findings in patients with NCC, and their conclusions are variable and contradictory. The aim of our study was to describe DWI findings of a cohort of patients with NCC, emphasizing the frequency of reduced diffusion. MATERIALS AND METHODS: This retrospective study included 48 patients with NCC. Two neuroradiologists analyzed MR images regarding location, number, and stage of NCC lesions. On the basis of visual analysis, they defined, by consensus, the presence of high signal within NCC lesions on DWI and measured their ADC values when feasible. RESULTS: The total number of lesions was 342: parenchymal (263), subarachnoid (65), and intraventricular (14); 83 were DWI hyperintense. The first pattern was a small eccentric hyperintense dot/curvilinear structure on DWI (representing the scolex) noted in intraparenchymal lesions in vesicular (41 lesions, 29%) and colloidal vesicular (18 lesions, 19%) stages, in 14 (22%) subarachnoid lesions, and 2 (14%) intraventricular lesions; rADC calculations were hampered by the intrinsic small dimensions of this finding. The second pattern was the presence of total/subtotal DWI hyperintensity in intraparenchymal lesions, 5 in the colloidal vesicular stage (5%) and 1 in the granular nodular phase (3%). Two subarachnoid lesions also showed the same presentation; in this second pattern, reduced diffusion was present in different degrees, measured by rADC calculations. CONCLUSIONS: DWI may identify the scolex, increasing diagnostic confidence for NCC. Total/subtotal DWI hyperintensity, related to the stage of the lesion, though uncommon, allows including NCC as a consideration in the differential diagnosis of lesions with reduced diffusion and ring enhancement.
Palavras-chave
Referências
- Amaral L, 2003, ARQ NEURO-PSIQUIAT, V61, P533, DOI 10.1590/S0004-282X2003000400002
- Bergui M, 2001, NEURORADIOLOGY, V43, P824
- Campbell G, 2006, PARASITOL INT, V55, pS121, DOI 10.1016/j.parint.2005.11.019
- Carabin H, 2011, PLOS NEGLECT TROP D, V5, DOI 10.1371/journal.pntd.0001152
- Carpio A, 2002, LANCET INFECT DIS, V2, P751, DOI 10.1016/S1473-3099(02)00454-1
- Del Brutto OH, 2001, NEUROLOGY, V57, P177
- Ebisu T, 1996, MAGN RESON IMAGING, V14, P1113, DOI 10.1016/S0730-725X(96)00237-8
- do Amaral Lázaro Luís Faria, 2005, Top Magn Reson Imaging, V16, P127
- Garcia HH, 2003, ACTA TROP, V87, P71, DOI 10.1016/S0001-706X(03)00057-3
- Gaviani P, 2005, AM J NEURORADIOL, V26, P1115
- Gupta RK, 2005, EUR J RADIOL, V55, P384, DOI 10.1016/j.ejrad.2005.02.003
- Gupta RK, 2012, MAGN RESON IMAGING, V30, P104, DOI 10.1016/j.mri.2011.07.027
- Hakyemez B, 2005, EUR J RADIOL, V54, P214, DOI 10.1016/j.ejrad.2004.06.018
- Hawk MW, 2005, SURG NEUROL, V63, P123, DOI 10.1016/j.surneu.2004.02.033
- Kim YJ, 1998, AM J ROENTGENOL, V171, P1487
- Kimura-Hayama ET, 2010, RADIOGRAPHICS, V30, P1705, DOI 10.1148/rg.306105522
- Kraft R, 2007, AM FAM PHYSICIAN, V76, P91
- Lucato LT, 2007, AM J NEURORADIOL, V28, P1501, DOI 10.3174/ajnr.A0623
- Maldjian JA, 2001, AM J NEURORADIOL, V22, P112
- Mishra AM, 2004, J COMPUT ASSIST TOMO, V28, P540, DOI 10.1097/00004728-200407000-00017
- Mont'Alverne FEF, 2011, ARQ NEURO-PSIQUIAT, V69, P74, DOI 10.1590/S0004-282X2011000100015
- Narata AP, 1998, ARQ NEURO-PSIQUIAT, V56, P245, DOI 10.1590/S0004-282X1998000200013
- Noujaim SE, 1999, AM J ROENTGENOL, V173, P1485
- Park SH, 2000, NEURORADIOLOGY, V42, P716
- Pittella JEH, 1997, BRAIN PATHOL, V7, P681, DOI 10.1111/j.1750-3639.1997.tb01083.x
- Raffin LS, 2001, ARQ NEURO-PSIQUIAT, V59, P839, DOI 10.1590/S0004-282X2001000600001
- Razek AAKA, 2011, NEUROIMAG CLIN N AM, V21, P815, DOI 10.1016/j.nic.2011.07.005
- Reddy JS, 2006, SURG NEUROL, V66, P246, DOI 10.1016/j.surneu.2006.03.032
- Schaefer PW, 2000, RADIOLOGY, V217, P331
- Sinha S, 2009, J CLIN NEUROSCI, V16, P867, DOI 10.1016/j.jocn.2008.10.030
- TSURUDA JS, 1990, AM J NEURORADIOL, V11, P925