Are pediatricians familiar with hereditary angioedema?

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art_CHONG-NETO_Are_pediatricians_familiar_with_hereditary_angioedema_2023.PDF (239.7 KB)
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article
Data de publicação
2023
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Scopus
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Autores
CHONG-NETO, Herberto Jose
ARONI, Barbara Padilha
MANSOUR, Eli
TOLEDO, Eliana
SERPA, Faradiba Sarquis
ARRUDA, Luisa Karla
VALLE, Solange Oliveira Rodrigues
MORAES, Caroline Guth de Freitas Batista de
KRUK, Tatielly
Citação
WORLD ALLERGY ORGANIZATION JOURNAL, v.16, n.6, article ID 100783, 10p, 2023
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Background: Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of subcutaneous or mucosal edema caused by excess bradykinin. The aim of the present study was to assess the knowledge of pediatricians about hereditary angioedema. Methods: An online survey with 12 HAE-related and 14 demographics-related questions was e-mailed to all pediatricians who were members of the Brazilian Society of Pediatrics (n 1/4 17 145) once a week during the months of June and July 2021. The electronic questionnaire assessed clinical manifestations, diagnosis, and treatment of hereditary angioedema in children and adolescents. Results: Four hundred and fifty-five pediatricians responded to the questionnaire (2.6%), of whom 55 (12.1%) were board certified in Allergy and Immunology (A/I), while 400 (87.9%) were not (N-A/I). Three hundred and sixty-eight (80.9%) were female, 289 (55.7%) were under 50 years of age, 286 (62.9%) graduated from Medical School more than 10 years previously, 83 (18.2%) held an MSc/PhD degree, and 253 (55.6%) were living in the Southeast Region of Brazil. The median number of correct answers to the questions related to HAE among A/I was 7 out of 12 (58.3%), with median ranging from 4.5 to 8 correct answers, while for N-A/I it was 3 (25%), with median ranging from 2.5 to 4 correct answers (p < 0.001). Conclusion: Knowledge about HAE among Brazilian pediatricians, whether board certified in Allergy and Immunology or not, was unsatisfactory. HAE is a rare disease, largely unknown among physicians; therefore, increasing awareness may lead to improvement in diagnosis and treatment.
Palavras-chave
Angioedema, Hereditary, Pediatrics, Knowledge, Surveys Questionnaires
URI
https://observatorio.fm.usp.br/handle/OPI/55984
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - LIM/60