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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | MACEDO, Delanie B. | - |
dc.contributor.author | CUKIER, Priscilla | - |
dc.contributor.author | MENDONCA, Berenice B. | - |
dc.contributor.author | LATRONICO, Ana Claudia | - |
dc.contributor.author | BRITO, Vinicius Nahime | - |
dc.date.accessioned | 2014-09-30T14:38:12Z | - |
dc.date.available | 2014-09-30T14:38:12Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA, v.58, n.2, Special Issue, p.108-117, 2014 | - |
dc.identifier.issn | 0004-2730 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/7363 | - |
dc.description.abstract | The onset of puberty is first detected as an increase in the amplitude and frequency of pulses of gonadotropin-releasing hormone (GnRH) after a quiescent period during childhood. The reemergence of pulsatile GnRH secretion leads to increases in the secretion of the gonadotropins, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) by the pituitary gland, and the consequent activation of gonadal function. Early activation of the hypothalamic-pituitary-gonadal axis results in gonadotropin-dependent precocious puberty, also known as central precocious puberty (CPP), which is clinically defined by the development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. Pubertal timing is influenced by complex interactions among genetic, nutritional, environmental, and socioeconomic factors. CPP is diagnosed on the basis of clinical signs of progressive pubertal development before the age of 8 years in girls and 9 years in boys, pubertal basal and/or GnRH-stimulated LH levels, and advanced bone age. Magnetic resonance imaging of the central nervous system is essential for establishing the CPP form as organic or idiopathic. Depot GnRH-analogues represent the first-line of therapy in CPP. Very recently, the genetic component of CPP was demonstrated by the evidence that the deficiency of the MKRN3 gene, located on long arm of chromosome 15, causes familial CPP in humans. In this current review, clinical and therapeutic aspects of the CPP will be discussed, contributing to adequate diagnosis and criterious approach of this relevant condition of pediatric endocrinology. | - |
dc.language.iso | por | - |
dc.publisher | SBEM-SOC BRASIL ENDOCRINOLOGIA & METABOLOGIA | - |
dc.relation.ispartof | Arquivos Brasileiros de Endocrinologia e Metabologia | - |
dc.rights | openAccess | - |
dc.subject | Central precocious puberty | - |
dc.subject | hamartomas | - |
dc.subject | genetic mutations | - |
dc.subject | gonadotropins | - |
dc.subject | GnRH analogues | - |
dc.subject.other | genome-wide association | - |
dc.subject.other | sexual precocity | - |
dc.subject.other | hormone analog | - |
dc.subject.other | adult height | - |
dc.subject.other | final height | - |
dc.subject.other | neurobiological mechanisms | - |
dc.subject.other | hypothalamic hamartomas | - |
dc.subject.other | depot leuprolide | - |
dc.subject.other | growth-hormone | - |
dc.subject.other | girls | - |
dc.title | Advances in the etiology, diagnosis and treatment of central precocious puberty | - |
dc.title.alternative | Avanços na etiologia, no diagnóstico e no tratamento da puberdade precoce central | - |
dc.type | article | - |
dc.rights.holder | Copyright SBEM-SOC BRASIL ENDOCRINOLOGIA & METABOLOGIA | - |
dc.identifier.doi | 10.1590/0004-2730000002931 | - |
dc.identifier.pmid | 24830587 | - |
dc.subject.wos | Endocrinology & Metabolism | - |
dc.type.category | review | - |
dc.type.version | publishedVersion | - |
hcfmusp.description.beginpage | 108 | - |
hcfmusp.description.endpage | 117 | - |
hcfmusp.description.issue | 2 | - |
hcfmusp.description.issue | Special Issue | - |
hcfmusp.description.volume | 58 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | WOS:000336783400004 | - |
hcfmusp.origem.id | 2-s2.0-84900565915 | - |
hcfmusp.origem.id | SCIELO:S0004-27302014000200108 | - |
hcfmusp.publisher.city | RIO DE JANEIRO, RJ | - |
hcfmusp.publisher.country | BRAZIL | - |
hcfmusp.relation.reference | Abreu AP, 2013, NEW ENGL J MED, V368, P2467, DOI 10.1056/NEJMoa1302160 | - |
hcfmusp.relation.reference | Antoniazzi F, 2003, J CLIN ENDOCR METAB, V88, P1096, DOI 10.1210/jc.2002-021154 | - |
hcfmusp.relation.reference | Badaru A, 2006, J CLIN ENDOCR METAB, V91, P1862, DOI 10.1210/jc.2005-1500 | - |
hcfmusp.relation.reference | BAR A, 1995, J PEDIATR, V126, P955, DOI 10.1016/S0022-3476(95)70221-0 | - |
hcfmusp.relation.reference | Brito VN, 2004, J CLIN ENDOCR METAB, V89, P4338, DOI 10.1210/jc.2003-031537 | - |
hcfmusp.relation.reference | Brito VN, 2008, J CLIN ENDOCR METAB, V93, P2662, DOI 10.1210/jc.2007-2183 | - |
hcfmusp.relation.reference | Brito VN, 1999, J CLIN ENDOCR METAB, V84, P3539, DOI 10.1210/jc.84.10.3539 | - |
hcfmusp.relation.reference | Brito VN, 1999, ARCH DIS CHILD, V80, P231 | - |
hcfmusp.relation.reference | Brito VN, 2008, ARQ BRAS ENDOCRINOL, V52, P18, DOI 10.1590/S0004-27302008000100005 | - |
hcfmusp.relation.reference | Carel JC, 2009, PEDIATRICS, V123, pE752, DOI 10.1542/peds.2008-1783 | - |
hcfmusp.relation.reference | Carel JC, 2006, EUR J ENDOCRINOL, V154, P119, DOI 10.1530/eje.1.02056 | - |
hcfmusp.relation.reference | Carel JC, 2008, NEW ENGL J MED, V358, P2366, DOI 10.1056/NEJMcp0800459 | - |
hcfmusp.relation.reference | CAVALLO A, 1995, CLIN ENDOCRINOL, V42, P641, DOI 10.1111/j.1365-2265.1995.tb02692.x | - |
hcfmusp.relation.reference | Chiocca E, 2009, NEUROENDOCRINOLOGY, V89, P441, DOI 10.1159/000197862 | - |
hcfmusp.relation.reference | Cukier P, 2013, SEIZURE-EUR J EPILEP, V22, P28, DOI 10.1016/j.seizure.2012.09.013 | - |
hcfmusp.relation.reference | de Vries L, 2004, J CLIN ENDOCR METAB, V89, P1794, DOI 10.1210/jc.2003-030361 | - |
hcfmusp.relation.reference | Eckert KL, 1996, PEDIATRICS, V97, P517 | - |
hcfmusp.relation.reference | Eugster EA, 2007, J CLIN ENDOCR METAB, V92, P1967 | - |
hcfmusp.relation.reference | Franceschi R, 2010, FERTIL STERIL, V93, P1185, DOI 10.1016/j.fertnstert.2008.11.016 | - |
hcfmusp.relation.reference | Freeman JL, 2003, EPILEPTIC DISORD, V5, P177 | - |
hcfmusp.relation.reference | Gray TA, 2000, GENOMICS, V66, P76, DOI 10.1006/geno.2000.6199 | - |
hcfmusp.relation.reference | Greulich WW, 1971, RADIOGRAPHIC ATLAS S | - |
hcfmusp.relation.reference | Grumbach MM, 2002, HORM RES, V57, P2, DOI 10.1159/000058094 | - |
hcfmusp.relation.reference | He CY, 2009, NAT GENET, V41, P724, DOI 10.1038/ng.385 | - |
hcfmusp.relation.reference | Heger S, 2005, ENDOCRIN DEV, V8, P94 | - |
hcfmusp.relation.reference | HermanGiddens ME, 1997, PEDIATRICS, V99, P505, DOI 10.1542/peds.99.4.505 | - |
hcfmusp.relation.reference | Lazar L, 2007, J CLIN ENDOCR METAB, V92, P3483, DOI 10.1210/jc.2007-0321 | - |
hcfmusp.relation.reference | MARSHALL WA, 1969, ARCH DIS CHILD, V44, P291 | - |
hcfmusp.relation.reference | MARSHALL WA, 1970, ARCH DIS CHILD, V45, P13 | - |
hcfmusp.relation.reference | NEELY EK, 1995, J PEDIATR, V127, P40, DOI 10.1016/S0022-3476(95)70254-7 | - |
hcfmusp.relation.reference | Ojeda SR, 2006, ENDOCRINOLOGY, V147, P1166, DOI 10.1210/en.2005-1136 | - |
hcfmusp.relation.reference | Ong KK, 2009, NAT GENET, V41, P729, DOI 10.1038/ng.382 | - |
hcfmusp.relation.reference | Palmert MR, 2001, J CLIN ENDOCR METAB, V86, P2364, DOI 10.1210/jc.86.6.2364 | - |
hcfmusp.relation.reference | Parent AS, 2003, ENDOCR REV, V24, P668, DOI 10.1210/er.2002-0019 | - |
hcfmusp.relation.reference | Partsch CJ, 2002, CLIN ENDOCRINOL, V56, P129, DOI 10.1046/j.0300-0664.2001.01490.x | - |
hcfmusp.relation.reference | Partsch CJ, 2001, HUM REPROD UPDATE, V7, P292, DOI 10.1093/humupd/7.3.292 | - |
hcfmusp.relation.reference | Pasquino AM, 1996, J CLIN ENDOCR METAB, V81, P948, DOI 10.1210/jc.81.3.948 | - |
hcfmusp.relation.reference | Patisaul HB, 2013, ADV EXP MED BIOL, V784, P455, DOI 10.1007/978-1-4614-6199-9_21 | - |
hcfmusp.relation.reference | Perry JRB, 2009, NAT GENET, V41, P648, DOI 10.1038/ng.386 | - |
hcfmusp.relation.reference | Plant TM, 2004, HUM REPROD UPDATE, V10, P67, DOI 10.1093/humupd/dmh001 | - |
hcfmusp.relation.reference | Pucarelli I, 2003, J PEDIATR ENDOCR MET, V16, P1005 | - |
hcfmusp.relation.reference | Resende EAMR, 2007, J CLIN ENDOCR METAB, V92, P1424, DOI 10.1210/jc.2006-1569 | - |
hcfmusp.relation.reference | Silveira LFG, 2010, MOL CELL ENDOCRINOL, V324, P30, DOI 10.1016/j.mce.2010.02.023 | - |
hcfmusp.relation.reference | Silveira LG, 2010, J CLIN ENDOCR METAB, V95, P2276, DOI 10.1210/jc.2009-2421 | - |
hcfmusp.relation.reference | Silveira-Neto AP, 2012, HORM RES PAEDIAT, V78, P144, DOI 10.1159/000342212 | - |
hcfmusp.relation.reference | Soriano-Guillen L, 2011, AN PEDIATR, V74, P336, DOI 10.1016/j.anpedi.2010.11.003 | - |
hcfmusp.relation.reference | Sulem P, 2009, NAT GENET, V41, P734, DOI 10.1038/ng.383 | - |
hcfmusp.relation.reference | Teles MG, 2008, NEW ENGL J MED, V358, P709, DOI 10.1056/NEJMoa073443 | - |
hcfmusp.relation.reference | Terasawa E, 2001, ENDOCR REV, V22, P111, DOI 10.1210/er.22.1.111 | - |
hcfmusp.relation.reference | Tusset C, 2012, ARQ BRAS ENDOCRINOL, V56, P646, DOI 10.1590/S0004-27302012000900008 | - |
dc.description.index | MEDLINE | - |
dc.identifier.eissn | 1677-9487 | - |
hcfmusp.citation.scopus | 14 | - |
hcfmusp.scopus.lastupdate | 2024-04-12 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCM Artigos e Materiais de Revistas Científicas - HC/ICESP Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/42 |
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