Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/7626
Title: | Health-related quality of life of children and adolescents with CKD stages 4-5 and their caregivers |
Authors: | LOPES, Marcos; FERRARO, Alexandre; KOCH, Vera H. |
Citation: | PEDIATRIC NEPHROLOGY, v.29, n.7, p.1239-1247, 2014 |
Abstract: | Renal replacement therapies may affect the quality of life of patients and their primary caregivers (PC). This study describes the perception of health-related quality of life (HRQoL) of children/adolescents with CKD stages 4-5, as well as of their PC (n = 64), in comparison to healthy peers and their PC (n = 129), respectively, based on the Peds QL (TM) 4.0 and Short Form-36 (SF-36) questionnaires and selected biomarkers. Patients reported a deleterious impact on physical capacity and on social and school activities. A negative influence on emotional aspects was reported by older patients, but not by their PC. Hemodialysis, followed by peritoneal dialysis, had a more negative impact on patients' physical functioning domain. PC HRQol proxy reports differed from those of their children, especially in older patients. PC of both groups presented similar SF-36 scores. An association was demonstrated between the magnitude of treatment target inadequacies, lower specific dominion scores in the patients/PC proxy reports and PC SF-36 general health scores. The HRQoL of patients with CKD stages 4-5 is negatively affected to different degrees depending on age and treatment modality. The results suggest an association between worsening HRQoL parameters and inadequate control of recognized therapeutic CKD treatment targets. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MPE Artigos e Materiais de Revistas Científicas - HC/ICr Artigos e Materiais de Revistas Científicas - LIM/21 Artigos e Materiais de Revistas Científicas - LIM/36 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_LOPES_Health_related_quality_of_life_of_children_and_2014.PDF Restricted Access | publishedVersion (English) | 333.8 kB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.