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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | WOLOSZYNEK, Renata Reis | - |
dc.contributor.author | BRITO, Luciana Pinto | - |
dc.contributor.author | BATISTA, Marcelo Cidade | - |
dc.contributor.author | VALASSI, Helena Panteliou Lima | - |
dc.contributor.author | MENDONCA, Berenice Bilharinho | - |
dc.contributor.author | BRITO, Vinicius Nahime | - |
dc.date.accessioned | 2015-04-22T22:06:21Z | - |
dc.date.available | 2015-04-22T22:06:21Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | ANNALS OF CLINICAL BIOCHEMISTRY, v.52, n.1, p.67-75, 2015 | - |
dc.identifier.issn | 0004-5632 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/8897 | - |
dc.description.abstract | Background Anti-Mullerian hormone is marker of ovarian and testicular reserve. The clinical use of this hormone requires proper standardization of reference intervals. The aims of this study were to validate the Anti-Mullerian hormone Gen II immunoassay, to establish Anti-Mullerian hormone reference intervals in healthy subjects, and to evaluate the influence of hormonal contraceptives, smoking, and body mass index on Anti-Mullerian hormone. Methods The validation of the Anti-Mullerian hormone Gen II assay (Beckman Coulter Company, TX, USA) was performed using a simplified protocol recommended by Clinical Laboratory Standard Institute. One-hundred and thirty-three healthy females and 120 males were prospectively selected for this study. Results The analytical and functional sensitivities of the Anti-Mullerian hormone Gen II immunoassay were 0.02 and 0.2ng/mL, respectively. Intra-assay coefficients ranged from 5.2 to 9.0%, whereas inter-assay precision ranged from 4.6 to 7.8% at different concentrations. In females, Anti-Mullerian hormone showed progressive decline with increasing age (r=-0.4, p<0.001), whereas in males, age showed no influence on Anti-Mullerian hormone concentrations. In females, Anti-Mullerian hormone concentrations did not differ between users and non-users of hormonal contraceptives, smokers, and non-smokers and obese and lean individuals. However, there was a negative and significant correlation between Anti-Mullerian hormone and body mass index in males (r=-0.3, p=0.008). Conclusions Anti-Mullerian hormone Gen II assay was reliable for determining serum Anti-Mullerian hormone concentrations. Anti-Mullerian hormone concentrations declined with aging and presented a wide inter-individual variability. The lack of influence of hormonal contraceptives, smoking, and obesity on Anti-Mullerian hormone in both sexes allowed us to refine the normative concentrations for the Brazilian population. | - |
dc.description.sponsorship | Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2011/2129070, 2012/205258] | - |
dc.language.iso | eng | - |
dc.publisher | SAGE PUBLICATIONS INC | - |
dc.relation.ispartof | Annals of Clinical Biochemistry | - |
dc.rights | restrictedAccess | - |
dc.subject | Clinical studies | - |
dc.subject | endocrinology | - |
dc.subject | immunoassay | - |
dc.subject.other | reproductive-age women | - |
dc.subject.other | ovarian reserve | - |
dc.subject.other | antimullerian hormone | - |
dc.subject.other | prospective cohort | - |
dc.subject.other | amh | - |
dc.subject.other | obesity | - |
dc.subject.other | marker | - |
dc.subject.other | assay | - |
dc.subject.other | hypogonadism | - |
dc.subject.other | population | - |
dc.title | Validation of an immunoassay for anti-Mullerian hormone measurements and reference intervals in healthy Brazilian subjects | - |
dc.type | article | - |
dc.rights.holder | Copyright SAGE PUBLICATIONS INC | - |
dc.identifier.doi | 10.1177/0004563214554462 | - |
dc.identifier.pmid | 25249661 | - |
dc.subject.wos | Medical Laboratory Technology | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.description.beginpage | 67 | - |
hcfmusp.description.endpage | 75 | - |
hcfmusp.description.issue | 1 | - |
hcfmusp.description.volume | 52 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84918817388 | - |
hcfmusp.origem.id | WOS:000346418300008 | - |
hcfmusp.publisher.city | THOUSAND OAKS | - |
hcfmusp.publisher.country | USA | - |
hcfmusp.relation.reference | Aksglaede L, 2010, J CLIN ENDOCR METAB, V95, P5357, DOI 10.1210/jc.2010-1207 | - |
hcfmusp.relation.reference | Al-Qahtani A, 2005, CLIN ENDOCRINOL, V63, P267, DOI 10.1111/j.1365-2265.2005.02336.x | - |
hcfmusp.relation.reference | Bentzen JG, 2012, REPROD BIOMED ONLINE, V25, P612, DOI 10.1016/j.rbmo.2012.09.001 | - |
hcfmusp.relation.reference | Broekmans FJ, 2008, TRENDS ENDOCRIN MET, V19, P340, DOI 10.1016/j.tem.2008.08.002 | - |
hcfmusp.relation.reference | Brougham MFH, 2012, J CLIN ENDOCR METAB, V97, P2059, DOI 10.1210/jc.2011-3180 | - |
hcfmusp.relation.reference | Celik HG, 2012, FERTIL STERIL, V97, P1472, DOI 10.1016/j.fertnstert.2012.03.027 | - |
hcfmusp.relation.reference | Coutant R, 2010, J CLIN ENDOCR METAB, V95, P5225, DOI 10.1210/jc.2010-1535 | - |
hcfmusp.relation.reference | Dewailly D, 2014, HUM REPROD UPDATE, V20, P370, DOI 10.1093/humupd/dmt062 | - |
hcfmusp.relation.reference | Freeman EW, 2007, FERTIL STERIL, V87, P101, DOI 10.1016/j.fertnstert.2006.05.074 | - |
hcfmusp.relation.reference | Freeman EW, 2012, J CLIN ENDOCR METAB, V97, P1673, DOI 10.1210/jc.2011-3032 | - |
hcfmusp.relation.reference | Grinspon RP, 2010, HORM RES PAEDIAT, V73, P81, DOI 10.1159/000277140 | - |
hcfmusp.relation.reference | Grinspon RP, 2011, INT J ANDROL, V34, pE487, DOI 10.1111/j.1365-2605.2011.01210.x | - |
hcfmusp.relation.reference | Hagen CP, 2012, FERTIL STERIL, V98, P1602, DOI 10.1016/j.fertnstert.2012.08.008 | - |
hcfmusp.relation.reference | Hagen CP, 2010, J CLIN ENDOCR METAB, V95, P5003, DOI 10.1210/jc.2010-0930 | - |
hcfmusp.relation.reference | Halawaty Samir, 2010, J Obstet Gynaecol Can, V32, P687 | - |
hcfmusp.relation.reference | Hansen KR, 2011, FERTIL STERIL, V95, P170, DOI 10.1016/j.fertnstert.2010.04.006 | - |
hcfmusp.relation.reference | Homburg R, 2013, HUM REPROD, V28, P1077, DOI 10.1093/humrep/det015 | - |
hcfmusp.relation.reference | Josso N, 2013, INT J ENDOCRINOL, DOI 10.1155/2013/674105 | - |
hcfmusp.relation.reference | Kalaiselvi V S, 2012, J Clin Diagn Res, V6, P1636, DOI 10.7860/JCDR/2012/5101.2624 | - |
hcfmusp.relation.reference | Kallio S, 2012, FERTIL STERIL | - |
hcfmusp.relation.reference | Kuiri-Hanninen T, 2011, J CLIN ENDOCR METAB, V96, P3432, DOI 10.1210/jc.2011-1502 | - |
hcfmusp.relation.reference | Kumar A, 2010, J IMMUNOL METHODS, V362, P51, DOI 10.1016/j.jim.2010.08.011 | - |
hcfmusp.relation.reference | La Marca A, 2012, EUR J OBSTET GYN R B, V163, P180, DOI 10.1016/j.ejogrb.2012.04.013 | - |
hcfmusp.relation.reference | La Marca A, 2010, HUM REPROD UPDATE, V16, P113, DOI 10.1093/humupd/dmp036 | - |
hcfmusp.relation.reference | Li HWR, 2011, CONTRACEPTION, V83, P582, DOI 10.1016/j.contraception.2010.09.007 | - |
hcfmusp.relation.reference | Li HWR, 2012, J ASSIST REPROD GEN, V29, P1443, DOI 10.1007/s10815-012-9880-1 | - |
hcfmusp.relation.reference | Lie Fong S, 2012, J Clin Endocrinol Metab, V97, P4650, DOI 10.1210/jc.2012-1440 | - |
hcfmusp.relation.reference | NCCLS, 2005, EP15A2 NCCLS | - |
hcfmusp.relation.reference | NCCLS, 2004, EP17A NCCLS | - |
hcfmusp.relation.reference | NCCLS, 2003, EP6A NCCLS | - |
hcfmusp.relation.reference | Nelson SM, 2011, REPROD BIOMED ONLINE, V23, P411, DOI 10.1016/j.rbmo.2011.06.011 | - |
hcfmusp.relation.reference | Pietilainen KH, 2012, J CLIN ENDOCR METAB, V97, pE161, DOI 10.1210/jc.2011-1697 | - |
hcfmusp.relation.reference | Plante Beth J, 2010, Menopause, V17, P571, DOI 10.1097/gme.0b013e3181c7deba | - |
hcfmusp.relation.reference | Rey Rodolfo, 2005, Arq Bras Endocrinol Metabol, V49, P26, DOI 10.1590/S0004-27302005000100005 | - |
hcfmusp.relation.reference | Rustamov O, 2012, HUM REPROD, V27, P3085, DOI 10.1093/humrep/des260 | - |
hcfmusp.relation.reference | Sahmay S, 2012, ARCH GYNECOL OBSTET, V286, P661, DOI 10.1007/s00404-012-2363-x | - |
hcfmusp.relation.reference | Sowers MR, 2010, ANN NY ACAD SCI, V1204, P95, DOI 10.1111/j.1749-6632.2010.05523.x | - |
hcfmusp.relation.reference | Steiner AZ, 2010, CONTRACEPTION, V81, P245, DOI 10.1016/j.contraception.2009.10.004 | - |
hcfmusp.relation.reference | Su HI, 2008, MENOPAUSE, V15, P857, DOI [10.1097/gme.0b013e318165981e, 10.1097/gme.0b01e318165981e] | - |
hcfmusp.relation.reference | van Rooij IAJ, 2005, FERTIL STERIL, V83, P979, DOI 10.1016/j.fertnstert.2004.11.029 | - |
hcfmusp.relation.reference | Wallace AM, 2011, ANN CLIN BIOCHEM, V48, P370, DOI 10.1258/acb.2011.010172 | - |
hcfmusp.relation.reference | Waylen AL, 2010, REPROD BIOMED ONLINE, V20, P861, DOI 10.1016/j.rbmo.2010.02.021 | - |
dc.description.index | MEDLINE | - |
dc.identifier.eissn | 1758-1001 | - |
hcfmusp.citation.scopus | 8 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCM Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/42 Artigos e Materiais de Revistas Científicas - ODS/03 |
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